Analysis of transforming growth factor-beta1-induced Ig germ-line gamma2b transcription and its implication for IgA isotype switching. (Q53627102)

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8 January 2020

title

Analysis of transforming growth factor-beta1-induced Ig germ-line gamma2b transcription and its implication for IgA isotype switching (English)

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8 January 2020

1

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8 January 2020

author name string

Goo-Young Seo

2

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8 January 2020

Ae-Jin Choi

3

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8 January 2020

Janet Stavnezer

4

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8 January 2020

Pyeung-Hyeun Kim

5

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8 January 2020

language of work or name

English

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publication date

1 March 2005

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European Journal of Immunology

8 January 2020

published in

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8 January 2020

volume

35

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8 January 2020

issue

3

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8 January 2020

page(s)

946-956

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Structure and expression of germ line immunoglobulin gamma 2b transcripts

8 January 2020

cites work

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Circular DNA is excised by immunoglobulin class switch recombination

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Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme

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AID: how does it aid antibody diversity?

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Activation-induced cytidine deaminase deaminates deoxycytidine on single-stranded DNA but requires the action of RNase

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Immunoglobulin isotype switching is inhibited and somatic hypermutation perturbed in UNG-deficient mice

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Staggered AID-dependent DNA double strand breaks are the predominant DNA lesions targeted to S mu in Ig class switch recombination

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Transcription enhances AID-mediated cytidine deamination by exposing single-stranded DNA on the nontemplate strand

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Molecular characterization of germ-line immunoglobulin A transcripts produced during transforming growth factor type beta-induced isotype switching

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Transforming growth factor beta 1 selectivity stimulates immunoglobulin G2b secretion by lipopolysaccharide-activated murine B cells

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Roles of Ets proteins, NF-kappa B and nocodazole in regulating induction of transcription of mouse germline Ig alpha RNA by transforming growth factor-beta 1.

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Smad3 and Smad4 mediate transforming growth factor-beta1-induced IgA expression in murine B lymphocytes.

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7 January 2021

Smad and AML proteins synergistically confer transforming growth factor beta1 responsiveness to human germ-line IgA genes

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7 January 2021

Mitogen- and IL-4-regulated expression of germ-line Ig gamma 2b transcripts: evidence for directed heavy chain class switching

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