HIV integration site selection: targeting in macrophages and the effects of different routes of viral entry. (Q53625219)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16647883%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

title

HIV integration site selection: targeting in macrophages and the effects of different routes of viral entry (English)

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20 January 2020

2

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20 January 2020

Jeremy Leipzig

3

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20 January 2020

Joseph R. Ecker

5

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20 January 2020

author name string

Stephen D Barr

1

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20 January 2020

Paul Shinn

4

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20 January 2020

Frederic D Bushman

6

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20 January 2020

publication date

2 May 2006

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20 January 2020

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20 January 2020

volume

14

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20 January 2020

issue

2

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20 January 2020

page(s)

218-225

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20 January 2020

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Macrophages and HIV-1: dangerous liaisons

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Macrophages archive HIV-1 virions for dissemination in trans

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HIV-1 integration in the human genome favors active genes and local hotspots

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Transcription start regions in the human genome are favored targets for MLV integration

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Retroviral DNA integration: ASLV, HIV, and MLV show distinct target site preferences

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A role for LEDGF/p75 in targeting HIV DNA integration

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Integration targeting by avian sarcoma-leukosis virus and human immunodeficiency virus in the chicken genome

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Integration site selection by HIV-based vectors in dividing and growth-arrested IMR-90 lung fibroblasts.

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Symmetrical base preferences surrounding HIV-1, avian sarcoma/leukosis virus, and murine leukemia virus integration sites

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Weak palindromic consensus sequences are a common feature found at the integration target sites of many retroviruses

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Selective degradation of integrated murine leukemia proviral DNA by deoxyribonucleases

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Integration by design

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Yeast retrotransposons: finding a nice quiet neighborhood

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Targeting survival: integration site selection by retroviruses and LTR-retrotransposons

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Genome-wide analysis of retroviral DNA integration

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HIV-1 integrase forms stable tetramers and associates with LEDGF/p75 protein in human cells

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LEDGF/p75 is essential for nuclear and chromosomal targeting of HIV-1 integrase in human cells

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Human cell proteins and human immunodeficiency virus DNA integration

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LEDGF/p75 determines cellular trafficking of diverse lentiviral but not murine oncoretroviral integrase proteins and is a component of functional lentiviral preintegration complexes

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Lens epithelium-derived growth factor/p75 prevents proteasomal degradation of HIV-1 integrase

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Structural basis for the recognition between HIV-1 integrase and transcriptional coactivator p75.

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Integration of murine leukemia virus DNA depends on mitosis

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Human immunodeficiency virus infection of cells arrested in the cell cycle

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Identification of the envelope V3 loop as the primary determinant of cell tropism in HIV-1.

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Interspersed repeats and other mementos of transposable elements in mammalian genomes

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Initial sequencing and analysis of the human genome

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Genome-wide analysis of chromosomal features repressing human immunodeficiency virus transcription.

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Retroviral vector integration occurs in preferred genomic targets of human bone marrow-repopulating cells

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Gene transfer by lentiviral vectors is limited by nuclear translocation and rescued by HIV-1 pol sequences

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