ATP-citrate lyase regulates cellular senescence via an AMPK- and p53-dependent pathway. (Q53228637)

12 May 2018

title

ATP-citrate lyase regulates cellular senescence via an AMPK- and p53-dependent pathway. (English)

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Ji-Eun Lee

object named as

Ji-Eun Lee

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author name string

Jong-Hyuk Lee

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Soon-Min Lee

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Jinmi Choi

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Tae Wan Kim

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Eun-Jung Cho

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Hong-Duk Youn

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language of work or name

English

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publication date

23 November 2014

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12 May 2018

published in

FEBS Journal

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volume

282

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issue

2

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12 May 2018

page(s)

361-371

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ATP citrate lyase inhibition can suppress tumor cell growth

cites work

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AMP-activated protein kinase induces a p53-dependent metabolic checkpoint

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Malondialdehyde inhibits an AMPK-mediated nuclear translocation and repression activity of ALDH2 in transcription.

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Cabin1 restrains p53 activity on chromatin.

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ATP-citrate lyase deficiency in the mouse

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Acetylation of yeast AMPK controls intrinsic aging independently of caloric restriction

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Acetylation of metabolic enzymes coordinates carbon source utilization and metabolic flux

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Senescence in tumours: evidence from mice and humans

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A nucleocytoplasmic malate dehydrogenase regulates p53 transcriptional activity in response to metabolic stress

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Ferritin binds and activates p53 under oxidative stress

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O-GlcNAc regulates pluripotency and reprogramming by directly acting on core components of the pluripotency network

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21 January 2018

Identifiers

DOI

10.1111/FEBS.13139

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12 May 2018

PubMed ID

25367309

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12 May 2018