MDM2 (murine double minute-2) links inflammation and tubular cell healing during acute kidney injury in mice. (Q53188377)

12 May 2018

title

MDM2 (murine double minute-2) links inflammation and tubular cell healing during acute kidney injury in mice. (English)

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12 May 2018

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4

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12 May 2018

author name string

Shrikant R Mulay

series ordinal

1

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12 May 2018

Dana Thomasova

series ordinal

2

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12 May 2018

Mi Ryu

series ordinal

3

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12 May 2018

language of work or name

English

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publication date

1 February 2012

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12 May 2018

published in

Kidney International

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12 May 2018

volume

81

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12 May 2018

issue

12

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12 May 2018

page(s)

1199-1211

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12 May 2018

https://scigraph.springernature.com/pub.10.1038/ki.2011.482

exact match

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cites work

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TLR4 activation mediates kidney ischemia/reperfusion injury

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Epithelial cell cycle arrest in G2/M mediates kidney fibrosis after injury

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Intrinsic epithelial cells repair the kidney after injury

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siRNA targeted to p53 attenuates ischemic and cisplatin-induced acute kidney injury

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Intravital two-photon microscopy assessment of renal protection efficacy of siRNA for p53 in experimental rat kidney transplantation models

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Critical contribution of the MDM2 acidic domain to p53 ubiquitination

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Mdm2 promotes the rapid degradation of p53

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Mdm2 is a RING finger-dependent ubiquitin protein ligase for itself and p53

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In vivo activation of the p53 pathway by small-molecule antagonists of MDM2

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Temporal activation of p53 by a specific MDM2 inhibitor is selectively toxic to tumors and leads to complete tumor growth inhibition

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Activation of p53 promotes renal injury in acute aristolochic acid nephropathy

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p53-Mediated oxidative stress and tubular injury in rats with glycerol-induced acute kidney injury

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Apoptosis in ischemic renal injury: roles of GTP depletion and p53.

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Ischemia reperfusion induces IFN regulatory factor 4 in renal dendritic cells, which suppresses postischemic inflammation and prevents acute renal failure

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In vivo transfection of NF-kappaB decoy oligodeoxynucleotides attenuate renal ischemia/reperfusion injury in rats

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MDM2 induces NF-kappaB/p65 expression transcriptionally through Sp1-binding sites: a novel, p53-independent role of MDM2 in doxorubicin resistance in acute lymphoblastic leukemia

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Immunoregulatory functions of mTOR inhibition.

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Critical protection from renal ischemia reperfusion injury by CD55 and CD59.

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Progressive glomerulosclerosis in type 2 diabetes is associated with renal histone H3K9 and H3K23 acetylation, H3K4 dimethylation and phosphorylation at serine 10.

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7 January 2021

Identifiers

DOI

10.1038/KI.2011.482

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12 May 2018

PubMed ID

22297670

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12 May 2018