MerTK as a therapeutic target in glioblastoma. (Q52765904)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28605477%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

title

MerTK as a therapeutic target in glioblastoma (English)

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22 March 2020

15

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22 March 2020

author name string

Jing Wu

1

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22 March 2020

Lauren N Frady

2

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22 March 2020

Ryan E Bash

3

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22 March 2020

Stephanie M Cohen

4

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22 March 2020

Allison N Schorzman

5

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22 March 2020

Yu-Ting Su

6

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22 March 2020

David M Irvin

7

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22 March 2020

William C Zamboni

8

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22 March 2020

Xiaodong Wang

9

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22 March 2020

Stephen V Frye

10

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22 March 2020

Matthew G Ewend

11

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22 March 2020

Erik P Sulman

12

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22 March 2020

Mark R Gilbert

13

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22 March 2020

H Shelton Earp

14

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22 March 2020

publication date

1 January 2018

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22 March 2020

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22 March 2020

volume

20

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22 March 2020

page(s)

92-102

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22 March 2020

issue

1

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describes a project that uses

22 March 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5761530/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Nivolumab for Recurrent Squamous-Cell Carcinoma of the Head and Neck

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The tumor microenvironment underlies acquired resistance to CSF-1R inhibition in gliomas

25 August 2018

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The MERTK/FLT3 inhibitor MRX-2843 overcomes resistance-conferring FLT3 mutations in acute myeloid leukemia

25 August 2018

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TAM receptors regulate multiple features of microglial physiology

25 August 2018

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The TAM family receptor tyrosine kinase TYRO3 is a negative regulator of type 2 immunity

25 August 2018

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Atezolizumab in patients with locally advanced and metastatic urothelial carcinoma who have progressed following treatment with platinum-based chemotherapy: a single-arm, multicentre, phase 2 trial

25 August 2018

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Phosphatidylserine is a global immunosuppressive signal in efferocytosis, infectious disease, and cancer

25 August 2018

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Core pathway mutations induce de-differentiation of murine astrocytes into glioblastoma stem cells that are sensitive to radiation but resistant to temozolomide.

25 August 2018

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The TAM receptor Mertk protects against neuroinvasive viral infection by maintaining blood-brain barrier integrity

25 August 2018

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Orally administered colony stimulating factor 1 receptor inhibitor PLX3397 in recurrent glioblastoma: an Ivy Foundation Early Phase Clinical Trials Consortium phase II study

25 August 2018

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Pembrolizumab versus Ipilimumab in Advanced Melanoma

25 August 2018

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Treating recurrent glioblastoma: an update

25 August 2018

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MERTK as negative regulator of human T cell activation

25 August 2018

1 reference

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The TAM family: phosphatidylserine sensing receptor tyrosine kinases gone awry in cancer.

25 August 2018

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The soft agar colony formation assay

25 August 2018

1 reference

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Receptor tyrosine kinases, TYRO3, AXL, and MER, demonstrate distinct patterns and complex regulation of ligand-induced activation

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5761530

UNC2025, a potent and orally bioavailable MER/FLT3 dual inhibitor

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5761530

The M1 and M2 paradigm of macrophage activation: time for reassessment

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5761530

Astrocytes mediate synapse elimination through MEGF10 and MERTK pathways

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5761530

CSF-1R inhibition alters macrophage polarization and blocks glioma progression

25 August 2018

1 reference

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MerTK inhibition in tumor leukocytes decreases tumor growth and metastasis

25 August 2018

1 reference

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T cell-derived protein S engages TAM receptor signaling in dendritic cells to control the magnitude of the immune response

25 August 2018

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Glioma grade is associated with the accumulation and activity of cells bearing M2 monocyte markers

25 August 2018

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25 August 2018

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MERTK receptor tyrosine kinase is a therapeutic target in melanoma.

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5761530

Neutralizing tumor-promoting chronic inflammation: a magic bullet?

25 August 2018

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Efficient clearance of early apoptotic cells by human macrophages requires M2c polarization and MerTK induction

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5761530

Mer receptor tyrosine kinase promotes invasion and survival in glioblastoma multiforme

25 August 2018

1 reference

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Microglia/macrophages promote glioma progression

25 August 2018

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Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm

25 August 2018

1 reference

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Inhibition of Mer and Axl receptor tyrosine kinases in astrocytoma cells leads to increased apoptosis and improved chemosensitivity

25 August 2018

1 reference

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Microglial action in glioma: a boon turns bane

25 August 2018

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IL-4 induces cathepsin protease activity in tumor-associated macrophages to promote cancer growth and invasion

25 August 2018

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Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial

25 August 2018

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TAM receptor tyrosine kinases: biologic functions, signaling, and potential therapeutic targeting in human cancer

25 August 2018

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Possible involvement of the M2 anti-inflammatory macrophage phenotype in growth of human gliomas.

25 August 2018

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Immunobiology of the TAM receptors

25 August 2018

1 reference

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Ectopic expression of the proto-oncogene Mer in pediatric T-cell acute lymphoblastic leukemia

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5761530

The chemokine system in diverse forms of macrophage activation and polarization

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5761530

Alternative activation of macrophages

25 August 2018

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25 August 2018

Identifiers

DOI

10.1093/NEUONC/NOX111

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28605477%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28605477%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

1 reference