Phospholipase C-gamma inhibition prevents EGF protection of intestinal cytoskeleton and barrier against oxidants. (Q52543418)

3 May 2018

title

Phospholipase C-gamma inhibition prevents EGF protection of intestinal cytoskeleton and barrier against oxidants. (English)

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3 May 2018

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A Banan

1

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3 May 2018

J Z Fields

series ordinal

2

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3 May 2018

Y Zhang

series ordinal

3

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3 May 2018

A Keshavarzian

series ordinal

4

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3 May 2018

publication date

1 August 2001

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3 May 2018

American Journal of Physiology - Gastrointestinal and Liver Physiology

published in

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3 May 2018

volume

281

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3 May 2018

issue

2

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3 May 2018

page(s)

G412-23

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3 May 2018

Big mitogen-activated protein kinase 1 (BMK1) is a redox-sensitive kinase

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Phosphatidylcholine could be the source of 1,2-DAG which activates protein kinase C in EGF-stimulated colon carcinoma cells (HT29).

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Oxidant-induced intestinal barrier disruption and its prevention by growth factors in a human colonic cell line: role of the microtubule cytoskeleton

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Key role of PKC and Ca2+ in EGF protection of microtubules and intestinal barrier against oxidants

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Relationship between polyamines, actin distribution, and gastric healing in rats.

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Prostaglandins protect human intestinal cells against ethanol injury by stabilizing microtubules: role of protein kinase C and enhanced calcium efflux

21 January 2018

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Carbonylation and disassembly of the F-actin cytoskeleton in oxidant induced barrier dysfunction and its prevention by epidermal growth factor and transforming growth factor alpha in a human colonic cell line

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iNOS upregulation mediates oxidant-induced disruption of F-actin and barrier of intestinal monolayers.

21 January 2018

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Cell migration is essential for sustained growth of keratinocyte colonies: the roles of transforming growth factor-alpha and epidermal growth factor

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SH3 domains direct cellular localization of signaling molecules

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Differential activation of mitogen-activated protein kinases by H2O2 and O2- in vascular smooth muscle cells

21 January 2018

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Insulin-like growth factor-I and platelet-derived growth factor-BB induce directed migration of human arterial smooth muscle cells via signaling pathways that are distinct from those of proliferation

21 January 2018

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A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

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Cell movement elicited by epidermal growth factor receptor requires kinase and autophosphorylation but is separable from mitogenesis

21 January 2018

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Mitogenic signaling from the egf receptor is attenuated by a phospholipase C-gamma/protein kinase C feedback mechanism

21 January 2018

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Epidermal growth factor receptor-mediated cell motility: phospholipase C activity is required, but mitogen-activated protein kinase activity is not sufficient for induced cell movement

21 January 2018

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Microtubular organization and its involvement in the biogenetic pathways of plasma membrane proteins in Caco-2 intestinal epithelial cells

21 January 2018

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EGF-Receptor phosphorylation and signaling are targeted by H2O2 redox stress

21 January 2018

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Regulation of chemotaxis by the platelet-derived growth factor receptor-beta

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Evidence of oxidant-induced injury to epithelial cells during inflammatory bowel disease

21 January 2018

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The human intestinal epithelial cell line Caco-2; pharmacological and pharmacokinetic applications

21 January 2018

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Two signaling molecules share a phosphotyrosine-containing binding site in the platelet-derived growth factor receptor

21 January 2018

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Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C

21 January 2018

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Epidermal growth factor receptor-stimulated intestinal epithelial cell migration requires phospholipase C activity

21 January 2018

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Phorbol esters, phospholipase C, and growth factors rapidly stimulate the phosphorylation of a Mr 80,000 protein in intact quiescent 3T3 cells

21 January 2018

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Epidermal growth factor stimulates the synthesis of cell-attachment proteins in the human breast cancer cell line PMC42.

21 January 2018

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Phospholipase C-gamma 1 and phosphatidylinositol 3 kinase are the downstream mediators of the PDGF receptor's mitogenic signal

21 January 2018

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Suppression of ruffling by the EGF receptor in chemotactic cells

21 January 2018

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Epidermal growth factor stimulates phospholipase D independent of phospholipase C, protein kinase C or phosphatidylinositol-3 kinase activation in immortalized rabbit corneal epithelial cells

21 January 2018

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Induction of a novel epidermal growth factor-secreting cell lineage by mucosal ulceration in human gastrointestinal stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.2001.281.2.G412

10.1152/AJPGI.2001.281.2.G412

21 January 2018

Identifiers

DOI

1 reference

3 May 2018

PubMed ID

11447022

1 reference

3 May 2018