Insulin expression in human thymus is modulated by INS VNTR alleles at the IDDM2 locus. (Q52196099)

26 April 2018

title

Insulin expression in human thymus is modulated by INS VNTR alleles at the IDDM2 locus. (English)

1 reference

26 April 2018

1 reference

Constantin Polychronakos

9

1 reference

26 April 2018

author name string

Vafiadis P

1

1 reference

26 April 2018

Bennett ST

2

1 reference

26 April 2018

Todd JA

3

1 reference

26 April 2018

Nadeau J

4

1 reference

26 April 2018

Grabs R

5

1 reference

26 April 2018

Goodyer CG

6

1 reference

26 April 2018

Wickramasinghe S

7

1 reference

26 April 2018

Colle E

8

1 reference

26 April 2018

language of work or name

English

0 references

publication date

1 March 1997

1 reference

26 April 2018

published in

Nature Genetics

1 reference

26 April 2018

volume

15

1 reference

26 April 2018

page(s)

289-292

1 reference

26 April 2018

issue

3

1 reference

26 April 2018

https://scigraph.springernature.com/pub.10.1038/ng0397-289

exact match

0 references

cites work

Insulin-IGF2 region on chromosome 11p encodes a gene implicated in HLA-DR4-dependent diabetes susceptibility

1 reference

https://api.crossref.org/works/10.1038%2FNG0397-289

IDDM2-VNTR-encoded susceptibility to type 1 diabetes: dominant protection and parental transmission of alleles of the insulin gene-linked minisatellite locus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG0397-289

The insulin gene is transcribed in the human thymus and transcription levels correlated with allelic variation at the INS VNTR-IDDM2 susceptibility locus for type 1 diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG0397-289

Autoimmune diabetes as a consequence of locally produced interleukin-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG0397-289

Allele specific inactivation of insulin 1 and 2, in the mouse yolk sac, indicates imprinting.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG0397-289

Parental imprinting effect at the INS-IGF2 diabetes susceptibility locus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG0397-289

Paternally transmitted IDDM2 influences diabetes susceptibility despite biallelic expression of the insulin gene in human pancreas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG0397-289

Mosaic and polymorphic imprinting of the WT1 gene in humans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG0397-289

Recombinant human preproinsulin. Expression, purification and reaction with insulin autoantibodies in sera from patients with insulin-dependent diabetes mellitus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG0397-289

Evidence for a differential avidity model of T cell selection in the thymus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG0397-289

Insulin prophylaxis in individuals at high risk of type I diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG0397-289

The minisatellite in the diabetes susceptibility locus IDDM2 regulates insulin transcription.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG0397-289

Imprinted and Genotype-specific Expression of Genes at theIDDM2Locus in Pancreas and Leucocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG0397-289

Functional Polymorphism in the Parental Imprinting of the Human IGF2R Gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG0397-289

Susceptibility to human type 1 diabetes at IDDM2 is determined by tandem repeat variation at the insulin gene minisatellite locus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG0397-289

Susceptibility to insulin dependent diabetes mellitus maps to a 4.1 kb segment of DNA spanning the insulin gene and associated VNTR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG0397-289

7 January 2021

Localization of a type I diabetes susceptibility locus to the variable tandem repeat region flanking the insulin gene

1 reference

https://api.crossref.org/works/10.1038%2FNG0397-289

7 January 2021

Insulin gene region-encoded susceptibility to IDDM maps upstream of the insulin gene

1 reference

https://api.crossref.org/works/10.1038%2FNG0397-289

7 January 2021

T-cell tolerance toward a transgenic beta-cell antigen and transcription of endogenous pancreatic genes in thymus

1 reference

https://api.crossref.org/works/10.1038%2FNG0397-289

7 January 2021

Extrathymic acquisition of tolerance by T lymphocytes

1 reference

https://api.crossref.org/works/10.1038%2FNG0397-289

7 January 2021

The paternally inherited insulin gene B allele (1,428 FokI site) confers protection from insulin-dependent diabetes in families

1 reference

https://api.crossref.org/works/10.1038%2FNG0397-289

7 January 2021

Conservation of a maternal-specific methylation signal at the human IGF2R locus

1 reference

https://api.crossref.org/works/10.1038%2FNG0397-289

7 January 2021

The physiological role of regulatory T cells in the prevention of autoimmunity: the function of the thymus in the generation of the regulatory T cell subset

1 reference

https://api.crossref.org/works/10.1038%2FNG0397-289

7 January 2021

The neural and neuro-endocrine component of the human thymus. II. Hormone immunoreactivity

1 reference

https://api.crossref.org/works/10.1038%2FNG0397-289

7 January 2021

Mechanisms of immune tolerance induction through the thymic expression of a peripheral tissue-specific protein

1 reference

https://api.crossref.org/works/10.1038%2FNG0397-289

7 January 2021

1 reference

https://api.crossref.org/works/10.1038%2FNG0397-289

7 January 2021

Autoantibodies to insulin and to proinsulin in type 1 diabetic patients and in at-risk probands differentiate only little between both antigens

1 reference

https://api.crossref.org/works/10.1038%2FNG0397-289

7 January 2021

Thymic selection and adaptability of cytotoxic T lymphocyte responses in transgenic mice expressing a viral protein in the thymus

1 reference

https://api.crossref.org/works/10.1038%2FNG0397-289

7 January 2021

Prevention of autoimmune diabetes in the BB rat by intrathymic islet transplantation at birth

1 reference

https://api.crossref.org/works/10.1038%2FNG0397-289

7 January 2021

Positive and negative thymocyte selection induced by different concentrations of a single peptide

1 reference

https://api.crossref.org/works/10.1038%2FNG0397-289

7 January 2021

Insulin-specific T cells are a predominant component of islet infiltrates in pre-diabetic NOD mice

1 reference

https://api.crossref.org/works/10.1038%2FNG0397-289

7 January 2021

Insulitis and diabetes in NOD mice reduced by prophylactic insulin therapy

1 reference

https://api.crossref.org/works/10.1038%2FNG0397-289

7 January 2021

Regulation of insulin gene expression by the IDDM associated, insulin locus haplotype

1 reference

https://api.crossref.org/works/10.1038%2FNG0397-289

7 January 2021

The search for IDDM susceptibility genes: the next generation

1 reference

https://api.crossref.org/works/10.1038%2FNG0397-289

7 January 2021

Insulin gene 5' flanking polymorphism. Length of class 1 alleles in number of repeat units

1 reference

https://api.crossref.org/works/10.1038%2FNG0397-289

7 January 2021

Identifiers

DOI

10.1038/NG0397-289

1 reference

26 April 2018

Dimensions Publication ID

1003193548

0 references

Fatcat ID

release_caqfdgpidfaxzfgxfkpgl567cq

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/caqfdgpidfaxzfgxfkpgl567cq

24 November 2022

mapped directly with Wikidata item

PubMed ID

9054944

1 reference

26 April 2018