Energetic and functional contribution of residues in the core binding factor beta (CBFbeta ) subunit to heterodimerization with CBFalpha. (Q52165310)

26 April 2018

title

Energetic and functional contribution of residues in the core binding factor beta (CBFbeta ) subunit to heterodimerization with CBFalpha. (English)

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26 April 2018

protein heterodimerization activity

main subject

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5

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author name string

Tang YY

1

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Shi J

2

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Zhang L

3

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Davis A

4

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Warren AJ

6

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Speck NA

7

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Bushweller JH

8

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language of work or name

English

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publication date

1 December 2000

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Journal of Biological Chemistry

published in

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volume

275

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issue

50

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page(s)

39579-39588

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PEBP2/PEA2 represents a family of transcription factors homologous to the products of the Drosophila runt gene and the human AML1 gene

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Cloning and characterization of subunits of the T-cell receptor and murine leukemia virus enhancer core-binding factor

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The Ig fold of the core binding factor alpha Runt domain is a member of a family of structurally and functionally related Ig-fold DNA-binding domains

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Biophysical characterization of interactions between the core binding factor alpha and beta subunits and DNA.

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Structural basis for the heterodimeric interaction between the acute leukaemia-associated transcription factors AML1 and CBFbeta

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Cbfa1, a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone development

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Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts

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Mutations involving the transcription factor CBFA1 cause cleidocranial dysplasia

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AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis

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Immunoglobulin motif DNA recognition and heterodimerization of the PEBP2/CBF Runt domain

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Solution structure of core binding factor beta and map of the CBF alpha binding site

21 January 2018

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Molecular insights into PEBP2/CBF beta-SMMHC associated acute leukemia revealed from the structure of PEBP2/CBF beta

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21 January 2018

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Superadditive and subadditive effects of "hot spot" mutations within the interfaces of placental ribonuclease inhibitor with angiogenin and ribonuclease A

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M007350200

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26 April 2018

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26 April 2018