DNA methyltransferase 1 (Q5205796)

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mammalian protein found in Homo sapiens
  • CXXC-type zinc finger protein 9
  • DNA (cytosine-5-)-methyltransferase 1
  • DNMT1
  • DNA methyltransferase HsaI
  • DNA (cytosine-5)-methyltransferase 1
  • DNA MTase HsaI
  • M.HsaI
  • MCMT
  • DNA (Cytosine-5-)-Methyltransferase 1
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Language Label Description Also known as
English
DNA methyltransferase 1
mammalian protein found in Homo sapiens
  • CXXC-type zinc finger protein 9
  • DNA (cytosine-5-)-methyltransferase 1
  • DNMT1
  • DNA methyltransferase HsaI
  • DNA (cytosine-5)-methyltransferase 1
  • DNA MTase HsaI
  • M.HsaI
  • MCMT
  • DNA (Cytosine-5-)-Methyltransferase 1

Statements

molecular function
protein binding
determination method
IPI
15 references
retrieved
8 April 2019
stated in
SUMOylation enhances DNA methyltransferase 1 activity
GOA
curator
UniProt
UniProt protein ID
P26358
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26358
determination method
IPI
retrieved
8 April 2019
stated in
UHRF1 plays a role in maintaining DNA methylation in mammalian cells
GOA
curator
UniProt
UniProt protein ID
P26358
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26358
determination method
IPI
retrieved
8 April 2019
stated in
The USP7/Dnmt1 complex stimulates the DNA methylation activity of Dnmt1 and regulates the stability of UHRF1
GOA
curator
UniProt
UniProt protein ID
P26358
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26358
determination method
IPI
retrieved
8 April 2019
stated in
Np95 interacts with de novo DNA methyltransferases, Dnmt3a and Dnmt3b, and mediates epigenetic silencing of the viral CMV promoter in embryonic stem cells
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26358
determination method
IPI
retrieved
8 April 2019
stated in
The interaction of the SRA domain of ICBP90 with a novel domain of DNMT1 is involved in the regulation of VEGF gene expression
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26358
determination method
IPI
retrieved
8 April 2019
stated in
RIP140 directs histone and DNA methylation to silence Ucp1 expression in white adipocytes
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26358
determination method
IPI
retrieved
8 April 2019
stated in
Recruitment of the de novo DNA methyltransferase Dnmt3a by Kaposi's sarcoma-associated herpesvirus LANA
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26358
determination method
IPI
retrieved
8 April 2019
stated in
SIRT1 deacetylates the DNA methyltransferase 1 (DNMT1) protein and alters its activities
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26358
determination method
IPI
retrieved
8 April 2019
stated in
Oxidative damage targets complexes containing DNA methyltransferases, SIRT1, and polycomb members to promoter CpG Islands
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26358
determination method
IPI
retrieved
8 April 2019
stated in
The Polycomb group protein EZH2 directly controls DNA methylation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26358
determination method
IPI
retrieved
8 April 2019
stated in
Enhancing the Cytotoxic Effects of PARP Inhibitors with DNA Demethylating Agents - A Potential Therapy for Cancer
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26358
determination method
IPI
retrieved
8 April 2019
stated in
Global mapping of herpesvirus-host protein complexes reveals a transcription strategy for late genes
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26358
determination method
IPI
retrieved
8 April 2019
stated in
A Protein Interaction between β-Catenin and Dnmt1 Regulates Wnt Signaling and DNA Methylation in Colorectal Cancer Cells.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26358
determination method
IPI
retrieved
8 April 2019
stated in
Regulation of DNMT1 stability through SET7-mediated lysine methylation in mammalian cells
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26358
determination method
IPI
retrieved
8 April 2019
stated in
A methylation and phosphorylation switch between an adjacent lysine and serine determines human DNMT1 stability
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26358
determination method
IPI
cell component
biological process
Gene Atlas image
PBB GE DNMT1 201697 s at fs.png
732 × 530; 12 KB
0 references

Identifiers

MeSH descriptor ID
D000076123
subject named as
DNA (Cytosine-5-)-Methyltransferase 1
0 references
 
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