Oxidative damage targets complexes containing DNA methyltransferases, SIRT1, and polycomb members to promoter CpG Islands (Q24297794)

Embryonic ectoderm development

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

1 reference

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13

Stephen B Baylin

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author name string

Heather M O'Hagan

1

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Wei Wang

2

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Subhojit Sen

3

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Christina Destefano Shields

4

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Stella S Lee

5

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Yang W Zhang

6

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Eriko G Clements

7

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Yi Cai

8

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Leander Van Neste

9

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Hariharan Easwaran

10

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Robert A Casero

11

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Cynthia L Sears

describes a project that uses

12

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language of work or name

English

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publication date

15 November 2011

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published in

Cancer Cell

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volume

20

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page(s)

606-19

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issue

5

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ImageJ

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3220885/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

limma

1 reference

Europe PubMed Central

22 June 2022

https://europepmc.org/article/PMC/3220885

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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Double strand breaks can initiate gene silencing and SIRT1-dependent onset of DNA methylation in an exogenous promoter CpG island

19 March 2017

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The Polycomb group protein EZH2 directly controls DNA methylation

19 March 2017

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Composition and histone substrates of polycomb repressive group complexes change during cellular differentiation

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DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development

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DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139

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DNMT1 and DNMT3b cooperate to silence genes in human cancer cells

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MEC1-dependent redistribution of the Sir3 silencing protein from telomeres to DNA double-strand breaks

19 March 2017

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A targeting sequence directs DNA methyltransferase to sites of DNA replication in mammalian nuclei

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Polycomb-mediated methylation on Lys27 of histone H3 pre-marks genes for de novo methylation in cancer

7 April 2017

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Polyamine catabolism contributes to enterotoxigenic Bacteroides fragilis-induced colon tumorigenesis

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Rapid and transient recruitment of DNMT1 to DNA double-strand breaks is mediated by its interaction with multiple components of the DNA damage response machinery.

27 September 2017

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CpG islands influence chromatin structure via the CpG-binding protein Cfp1.

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DNA methylation and complete transcriptional silencing of cancer genes persist after depletion of EZH2.

27 September 2017

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27 September 2017

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27 September 2017

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Targeting of mutant hogg1 in mammalian mitochondria and nucleus: effect on cellular survival upon oxidative stress

27 September 2017

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Inhibition of SIRT1 reactivates silenced cancer genes without loss of promoter DNA hypermethylation

27 September 2017

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27 September 2017

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27 September 2017

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Methylation of polycomb target genes in intestinal cancer is mediated by inflammation

27 September 2017

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27 September 2017

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Close encounters: RIDGEs, hyperacetylated chromatin, radiation breakpoints and genes differentially expressed in tumors cluster at specific human chromosome regions.

30 May 2018

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Developmental regulation of Eed complex composition governs a switch in global histone modification in brain.

29 November 2018

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10.1016/J.CCR.2011.09.012

29 November 2018

Identifiers

DOI

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413249

413249

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1 reference

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