Identification of Zfp521/ZNF521 as a cooperative gene for E2A-HLF to develop acute B-lineage leukemia. (Q51918384)

17 April 2018

title

Identification of Zfp521/ZNF521 as a cooperative gene for E2A-HLF to develop acute B-lineage leukemia. (English)

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17 April 2018

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N Yamasaki

1

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K Miyazaki

2

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A Nagamachi

3

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R Koller

4

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H Oda

5

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M Miyazaki

6

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T Sasaki

7

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Z-i Honda

8

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L Wolff

9

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T Inaba

10

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H Honda

11

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language of work or name

English

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publication date

11 January 2010

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17 April 2018

published in

Oncogene

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volume

29

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issue

13

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page(s)

1963-1975

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https://scigraph.springernature.com/pub.10.1038/onc.2009.475

exact match

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cites work

RTCGD: retroviral tagged cancer gene database

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The role of E2A-PBX1 in leukemogenesis

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E2A deficiency leads to abnormalities in alphabeta T-cell development and to rapid development of T-cell lymphomas

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E2A proteins are required for proper B cell development and initiation of immunoglobulin gene rearrangements

21 January 2018

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Perturbation of Ikaros isoform selection by MLV integration is a cooperative event in Notch(IC)-induced T cell leukemogenesis

21 January 2018

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Early hematopoietic zinc finger protein-zinc finger protein 521: a candidate regulator of diverse immature cells.

21 January 2018

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The E2A-HLF oncoprotein activates Groucho-related genes and suppresses Runx1.

21 January 2018

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Progression of interleukin-2 (IL-2)-dependent rat T cell lymphoma lines to IL-2-independent growth following activation of a gene (Gfi-1) encoding a novel zinc finger protein

21 January 2018

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Evi3, a zinc-finger protein related to EBFAZ, regulates EBF activity in B-cell leukemia

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2009.475

Expression of a conditional AML1-ETO oncogene bypasses embryonic lethality and establishes a murine model of human t(8;21) acute myeloid leukemia

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2009.475

Reversal of apoptosis by the leukaemia-associated E2A-HLF chimaeric transcription factor

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2009.475

Fusion of the leucine zipper gene HLF to the E2A gene in human acute B-lineage leukemia

21 January 2018

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Cell transformation mediated by homodimeric E2A-HLF transcription factors

21 January 2018

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SLUG, a ces-1-related zinc finger transcription factor gene with antiapoptotic activity, is a downstream target of the E2A-HLF oncoprotein

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2009.475

Inducible gene targeting in mice

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2009.475

Failure of B-cell differentiation in mice lacking the transcription factor EBF.

21 January 2018

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Oncogenic transcription factors in the human acute leukemias

21 January 2018

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Regulation of annexin II by cytokine-initiated signaling pathways and E2A-HLF oncoprotein

21 January 2018

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Retroviral insertional mutagenesis: tagging cancer pathways

21 January 2018

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Identification of functional hypoxia response elements in the promoter region of the DEC1 and DEC2 genes

21 January 2018

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Enhanced expression of p210BCR/ABL and aberrant expression of Zfp423/ZNF423 induce blast crisis of chronic myelogenous leukemia.

21 January 2018

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Overexpression/enhanced kinase activity of BCR/ABL and altered expression of Notch1 induced acute leukemia in p210BCR/ABL transgenic mice

21 January 2018

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Retroviral insertional mutagenesis identifies oncogene cooperation

21 January 2018

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E2A-HLF usurps control of evolutionarily conserved survival pathways

21 January 2018

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Transformation of bone marrow B-cell progenitors by E2a-Hlf requires coexpression of Bcl-2.

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2009.475

Disrupted differentiation and oncogenic transformation of lymphoid progenitors in E2A-HLF transgenic mice

21 January 2018

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Conditional MLL-CBP targets GMP and models therapy-related myeloproliferative disease.

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2009.475

Evi3, a common retroviral integration site in murine B-cell lymphoma, encodes an EBFAZ-related Krüppel-like zinc finger protein

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2009.475

Hypermethylation of the Ink4b locus in murine myeloid leukemia and increased susceptibility to leukemia in p15(Ink4b)-deficient mice

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2009.475

A Moloney murine leukemia virus-based retrovirus with 4070A long terminal repeat sequences induces a high incidence of myeloid as well as lymphoid neoplasms

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2009.475

Haploinsufficiency of Runx1/AML1 promotes myeloid features and leukaemogenesis in BXH2 mice.

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2009.475

E2A-HLF-mediated cell transformation requires both the trans-activation domains of E2A and the leucine zipper dimerization domain of HLF.

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2009.475

The helix-loop-helix gene E2A is required for B cell formation

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2009.475

21 January 2018

Identifiers

DOI

10.1038/ONC.2009.475

1 reference

17 April 2018

PubMed ID

20062079

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17 April 2018