Conditional MLL-CBP targets GMP and models therapy-related myeloproliferative disease. (Q33761368)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15635450%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

title

Conditional MLL-CBP targets GMP and models therapy-related myeloproliferative disease (English)

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7 January 2020

3

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7 January 2020

Patricia Ernst

6

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7 January 2020

10

Sandra S Zinkel

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13

Todd R Golub

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Stanley J Korsmeyer

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7 January 2020

author name string

Jing Wang

1

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7 January 2020

Hiromi Iwasaki

2

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7 January 2020

Phillip G Febbo

4

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7 January 2020

Aaron R Thorner

5

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7 January 2020

Ema Anastasiadou

7

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7 January 2020

Jeffery L Kutok

8

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7 January 2020

Scott C Kogan

9

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7 January 2020

Jill K Fisher

11

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7 January 2020

Jay L Hess

12

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7 January 2020

Scott A Armstrong

14

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7 January 2020

Koichi Akashi

15

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7 January 2020

publication date

6 January 2005

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7 January 2020

language of work or name

0 references

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7 January 2020

volume

24

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7 January 2020

issue

2

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7 January 2020

page(s)

368-381

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The Oncogene Nup98-HOXA9 Induces Gene Transcription in Myeloid Cells

7 January 2020

cites work

1 reference

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Transformation of myeloid progenitors by MLL oncoproteins is dependent on Hoxa7 and Hoxa9

21 June 2018

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Expression of a conditional AML1-ETO oncogene bypasses embryonic lethality and establishes a murine model of human t(8;21) acute myeloid leukemia

21 June 2018

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MLL translocations specify a distinct gene expression profile that distinguishes a unique leukemia

21 June 2018

1 reference

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MLL and CREB bind cooperatively to the nuclear coactivator CREB-binding protein

21 June 2018

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The amino terminus targets the mixed lineage leukemia (MLL) protein to the nucleolus, nuclear matrix and mitotic chromosomal scaffolds

21 June 2018

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MEIS1 and HOXA7 genes in human acute myeloid leukemia

21 June 2018

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21 June 2018

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The mll-AF9 gene fusion in mice controls myeloproliferation and specifies acute myeloid leukaemogenesis

21 June 2018

1 reference

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MLL, a mammalian trithorax- group gene, functions as a transcriptional maintenance factor in morphogenesis

21 June 2018

1 reference

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Hoxa9 transforms primary bone marrow cells through specific collaboration with Meis1a but not Pbx1b

21 June 2018

1 reference

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CREB-binding protein cooperates with transcription factor GATA-1 and is required for erythroid differentiation

21 June 2018

1 reference

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Effects ofHOX homeobox genes in blood cell differentiation

21 June 2018

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Activation of p53 Sequence-Specific DNA Binding by Acetylation of the p53 C-Terminal Domain

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=545811

MLL is fused to CBP, a histone acetyltransferase, in therapy-related acute myeloid leukemia with a t(11;16)(q23;p13.3)

21 June 2018

1 reference

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The CBP co-activator is a histone acetyltransferase

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=545811

An Mll-AF9 fusion gene made by homologous recombination causes acute leukemia in chimeric mice: a method to create fusion oncogenes

21 June 2018

1 reference

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Rearrangement of the MLL gene confers a poor prognosis in childhood acute lymphoblastic leukemia, regardless of presenting age.

21 June 2018

1 reference

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The t(7;11)(p15;p15) translocation in acute myeloid leukaemia fuses the genes for nucleoporin NUP98 and class I homeoprotein HOXA9

21 June 2018

1 reference

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Nuclear protein CBP is a coactivator for the transcription factor CREB

21 June 2018

1 reference

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Altered Hox expression and segmental identity in Mll-mutant mice

21 June 2018

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Purification and characterization of mouse hematopoietic stem cells

21 June 2018

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Lineage-restricted expression of homeobox-containing genes in human hematopoietic cell lines

21 June 2018

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Evi-2, a common integration site involved in murine myeloid leukemogenesis

21 June 2018

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Coordinate regulation of HOX genes in human hematopoietic cells

21 June 2018

1 reference

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Targeted oncogene activation by site-specific recombination in transgenic mice

21 June 2018

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The transcriptome of the leukemogenic homeoprotein HOXA9 in human hematopoietic cells

21 June 2018

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Genome‐wide analysis of acute myeloid leukemia with normal karyotype reveals a unique pattern of homeobox gene expression distinct from those with translocation‐mediated fusion events

30 October 2018

1 reference

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Acute myeloid leukemia with MLL rearrangements: clinicobiological features, prognostic impact and value of flow cytometry in the detection of residual leukemic cells

30 October 2018

1 reference

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Binding of p53 to the KIX domain of CREB binding protein. A potential link to human T-cell leukemia virus, type I-associated leukemogenesis

30 October 2018

1 reference

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Regulation of activity of the transcription factor GATA-1 by acetylation

30 October 2018

1 reference

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Chromosomal translocations in human cancer.

30 October 2018

1 reference

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ALL-1 gene rearrangements in DNA topoisomerase II inhibitor-related leukemia in children.

30 October 2018

1 reference

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Bethesda proposals for classification of nonlymphoid hematopoietic neoplasms in mice

30 October 2018

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12 December 2020

Classification, subtype discovery, and prediction of outcome in pediatric acute lymphoblastic leukemia by gene expression profiling

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12 December 2020

MLL-GAS7 transforms multipotent hematopoietic progenitors and induces mixed lineage leukemias in mice

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12 December 2020

Hoxa9 influences the phenotype but not the incidence of Mll-AF9 fusion gene leukemia

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12 December 2020

Very high frequency of lymphoma induction by a chemical carcinogen in pim-1 transgenic mice

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12 December 2020

HRX involvement in de novo and secondary leukemias with diverse chromosome 11q23 abnormalities

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12 December 2020

Rearrangements of the MLL gene in therapy-related acute myeloid leukemia in patients previously treated with agents targeting DNA-topoisomerase II

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12 December 2020

Cooperative activation of Hoxa and Pbx1-related genes in murine myeloid leukaemias

1 reference

12 December 2020

The t(11;16)(q23;p13) translocation in myelodysplastic syndrome fuses the MLL gene to the CBP gene

1 reference

12 December 2020

All patients with the T(11;16)(q23;p13.3) that involves MLL and CBP have treatment-related hematologic disorders

1 reference

12 December 2020

Identifiers

DOI

10.1038/SJ.EMBOJ.7600521

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15635450%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

1 reference

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7 January 2020

PubMed publication ID

15635450

1 reference