Chromatin remodeling resets the immune system to protect against autoimmune diabetes in mice. (Q51504244)

6 April 2018

title

Chromatin remodeling resets the immune system to protect against autoimmune diabetes in mice. (English)

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6 April 2018

author name string

Tejas Patel

1

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6 April 2018

Vasu Patel

2

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6 April 2018

Rajvir Singh

3

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6 April 2018

Sundararajan Jayaraman

4

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6 April 2018

publication date

15 February 2011

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6 April 2018

Immunology & Cell Biology

published in

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6 April 2018

volume

89

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6 April 2018

issue

5

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6 April 2018

page(s)

640-649

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6 April 2018

Translating the Histone Code

cites work

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.144

Histone deacetylase inhibitors as new cancer drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.144

The histone deacetylase inhibitor Trichostatin A modulates CD4+ T cell responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.144

Histone deacetylase inhibitors modulate renal disease in the MRL-lpr/lpr mouse.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.144

Histone deacetylase inhibitors: a new class of immunosuppressors targeting a novel signal pathway essential for CD154 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.144

Trichostatin A reverses skewed expression of CD154, interleukin-10, and interferon-gamma gene and protein expression in lupus T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.144

Deacetylase inhibition promotes the generation and function of regulatory T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.144

The histone deacetylase inhibitor trichostatin A upregulates regulatory T cells and modulates autoimmunity in NZB/W F1 mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.144

Trichostatin A attenuates airway inflammation in mouse asthma model

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.144

Transcriptional therapy with the histone deacetylase inhibitor trichostatin A ameliorates experimental autoimmune encephalomyelitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.144

A comprehensive review of interventions in the NOD mouse and implications for translation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.144

Checkpoints in the progression of autoimmune disease: lessons from diabetes models

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.144

Diversity of regulatory CD4+T cells controlling distinct organ-specific autoimmune diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.144

Inhibition of Th17 cells regulates autoimmune diabetes in NOD mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.144

Essential role for interferon-gamma and interleukin-6 in autoimmune insulin-dependent diabetes in NOD/Wehi mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.144

IL-12 administration accelerates autoimmune diabetes in both wild-type and IFN-gamma-deficient nonobese diabetic mice, revealing pathogenic and protective effects of IL-12-induced IFN-gamma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.144

Effect of tumor necrosis factor alpha on insulin-dependent diabetes mellitus in NOD mice. I. The early development of autoimmunity and the diabetogenic process

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.144

NO-mediated cytotoxicity contributes to multiple low-dose streptozotocin-induced diabetes but not to NOD diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.144

Interleukin-6 and diabetes: the good, the bad, or the indifferent?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.144

Distinct effects of T-bet in TH1 lineage commitment and IFN-gamma production in CD4 and CD8 T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.144

T cell factor 1 initiates the T helper type 2 fate by inducing the transcription factor GATA-3 and repressing interferon-gamma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.144

The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.144

Transfusion of nonobese diabetic mice with allogeneic newborn blood ameliorates autoimmune diabetes and modifies the expression of selected immune response genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.144

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.144

IFN-gamma-dependent regulatory circuits in immune inflammation highlighted in diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.144

Genetic absence of gamma-interferon delays but does not prevent diabetes in NOD mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.144

Interferon-gamma impacts at multiple points during the progression of autoimmune diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.144

Protection of nonobese diabetic mice from diabetes by gene(s) closely linked to IFN-gamma receptor loci.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.144

Innocuous IFNgamma induced by adjuvant-free antigen restores normoglycemia in NOD mice through inhibition of IL-17 production

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.144

Cytokine signalling in the beta-cell: a dual role for IFNgamma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.144

Cross-regulation of signaling pathways by interferon-gamma: implications for immune responses and autoimmune diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.144

T-bet is required for optimal production of IFN-gamma and antigen-specific T cell activation by dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.144

T-bet-deficient NOD mice are protected from diabetes due to defects in both T cell and innate immune system function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.144

Absence of the T-bet gene coding for the Th1-related transcription factor does not affect diabetes-associated phenotypes in Balb/c mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.144

Genetic and epigenetic networks controlling T helper 1 cell differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.144

IL-2 and its high-affinity receptor: genetic control of immunoregulation and autoimmunity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.144

Histone deacetylase inhibitors modify pancreatic cell fate determination and amplify endocrine progenitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.144

Selective inhibition of IL-2 gene expression by trichostatin A, a potent inhibitor of mammalian histone deacetylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.144

7 January 2021

Histone hyperacetylation is associated with amelioration of experimental colitis in mice

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.144

7 January 2021

Insulin-dependent diabetes in the NOD mouse model. II. Beta cell destruction in autoimmune diabetes is a TH2 and not a TH1 mediated event

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.144

7 January 2021

Systemic administration of IL-18 promotes diabetes development in young nonobese diabetic mice

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.144

7 January 2021

Prevention of diabetes in NOD mice treated with antibody to murine IFN gamma

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.144

7 January 2021

The effects of a nonimmunogenic form of murine soluble interferon-gamma receptor on the development of autoimmune diabetes in the NOD mouse

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.144

7 January 2021

Interferon-gamma receptor signaling is dispensable in the development of autoimmune type 1 diabetes in NOD mice

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.144

7 January 2021

Gamma interferon paradoxically inhibits the development of diabetes in the NOD mouse

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.144

7 January 2021

In vivo apoptosis of diabetogenic T cells in NOD mice by IFN-gamma/TNF-alpha

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.144

7 January 2021

Temporal dissection of T-bet functions

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.144

7 January 2021

Adoptive transfer of diabetes into immunodeficient NOD-scid/scid mice. Relative contributions of CD4+ and CD8+ T-cells from diabetic versus prediabetic NOD.NON-Thy-1a donors

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.144

7 January 2021

Identifiers

DOI

10.1038/ICB.2010.144

1 reference

6 April 2018

Dimensions Publication ID

1043570303

0 references

1 reference

6 April 2018