Histone deacetylase inhibitors modify pancreatic cell fate determination and amplify endocrine progenitors (Q36959997)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18710955%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

title

Histone deacetylase inhibitors modify pancreatic cell fate determination and amplify endocrine progenitors (English)

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12 January 2020

1

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12 January 2020

Raphael Scharfmann

series ordinal

3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18710955%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

author name string

Olivia Lenoir

series ordinal

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18710955%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

language of work or name

English

0 references

publication date

18 August 2008

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18710955%20AND%20SRC:MED&resulttype=core&format=json

Molecular and Cellular Biology

12 January 2020

published in

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12 January 2020

volume

28

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12 January 2020

page(s)

6373-6383

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12 January 2020

issue

20

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An illustrated review of early pancreas development in the mouse.

12 January 2020

cites work

1 reference

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Histone deacetylases 1 and 2 redundantly regulate cardiac morphogenesis, growth, and contractility

29 September 2017

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Embryonic endocrine pancreas and mature beta cells acquire alpha and PP cell phenotypes upon Arx misexpression.

29 September 2017

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Histone deacetylase 7 maintains vascular integrity by repressing matrix metalloproteinase 10

29 September 2017

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29 September 2017

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NKX6 transcription factor activity is required for alpha- and beta-cell development in the pancreas

29 September 2017

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The simultaneous loss of Arx and Pax4 genes promotes a somatostatin-producing cell fate specification at the expense of the alpha- and beta-cell lineages in the mouse endocrine pancreas

29 September 2017

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Histone modifications affect timing of oligodendrocyte progenitor differentiation in the developing rat brain

29 September 2017

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GDF11 modulates NGN3+ islet progenitor cell number and promotes beta-cell differentiation in pancreas development

29 September 2017

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Histone deacetylase inhibition-mediated neuronal differentiation of multipotent adult neural progenitor cells

29 September 2017

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Histone deacetylase 4 controls chondrocyte hypertrophy during skeletogenesis

29 September 2017

1 reference

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Histone deacetylases 5 and 9 govern responsiveness of the heart to a subset of stress signals and play redundant roles in heart development

29 September 2017

1 reference

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Regulation of mammalian epithelial differentiation and intestine development by class I histone deacetylases

29 September 2017

1 reference

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Opposing actions of Arx and Pax4 in endocrine pancreas development

29 September 2017

1 reference

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Identification of novel isoform-selective inhibitors within class I histone deacetylases

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2577441

Activated Notch1 prevents differentiation of pancreatic acinar cells and attenuate endocrine development

29 September 2017

1 reference

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Inhibition of histone deacetylase activity by butyrate

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2577441

Histone deacetylases (HDACs): characterization of the classical HDAC family

29 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2577441

Essential function of histone deacetylase 1 in proliferation control and CDK inhibitor repression

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2577441

Direct evidence for the pancreatic lineage: NGN3+ cells are islet progenitors and are distinct from duct progenitors

29 September 2017

1 reference

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Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

29 September 2017

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Valproic acid defines a novel class of HDAC inhibitors inducing differentiation of transformed cells

29 September 2017

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The bHLH transcription factor Mist1 is required to maintain exocrine pancreas cell organization and acinar cell identity

29 September 2017

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29 September 2017

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Histone deacetylase is a direct target of valproic acid, a potent anticonvulsant, mood stabilizer, and teratogen

29 September 2017

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29 September 2017

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29 September 2017

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Histone deacetylases, transcriptional control, and cancer

29 September 2017

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Regulation of the pancreatic islet-specific gene BETA2 (neuroD) by neurogenin 3.

29 September 2017

1 reference

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neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2577441

Structures of a histone deacetylase homologue bound to the TSA and SAHA inhibitors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2577441

Notch signalling controls pancreatic cell differentiation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2577441

The bHLH protein PTF1-p48 is essential for the formation of the exocrine and the correct spatial organization of the endocrine pancreas

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2577441

TGF-beta plays a key role in morphogenesis of the pancreatic islets of Langerhans by controlling the activity of the matrix metalloproteinase MMP-2

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2577441

Roles of histone acetyltransferases and deacetylases in gene regulation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2577441

Histone acetylation in chromatin structure and transcription

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2577441

Diabetes, defective pancreatic morphogenesis, and abnormal enteroendocrine differentiation in BETA2/neuroD-deficient mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2577441

PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2577441

Insulin-promoter-factor 1 is required for pancreas development in mice

29 September 2017

1 reference

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Trichostatin A and trapoxin: novel chemical probes for the role of histone acetylation in chromatin structure and function

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2577441

Potent and specific inhibition of mammalian histone deacetylase both in vivo and in vitro by trichostatin A

29 September 2017

1 reference

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The expression of a small fraction of cellular genes is changed in response to histone hyperacetylation.

29 September 2017

1 reference

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Deacetylase inhibition promotes the generation and function of regulatory T cells.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2577441

Glucose is necessary for embryonic pancreatic endocrine cell differentiation.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2577441

Temporal control of neurogenin3 activity in pancreas progenitors reveals competence windows for the generation of different endocrine cell types.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2577441

Primary cilia deletion in pancreatic epithelial cells results in cyst formation and pancreatitis.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2577441

Histone deacetylase 1-mediated histone modification regulates osteoblast differentiation.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2577441

Down-regulation of histone deacetylases stimulates adipocyte differentiation

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2577441

Histone deacetylase 1 regulates retinal neurogenesis in zebrafish by suppressing Wnt and Notch signaling pathways.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2577441

Label-retaining cells in the rat pancreas: location and differentiation potential in vitro.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2577441

Histone deacetylase activity is necessary for oligodendrocyte lineage progression.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2577441

Induction of pancreatic differentiation by signals from blood vessels.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2577441

Notochord to endoderm signaling is required for pancreas development.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2577441

Pancreatic epithelial plasticity mediated by acinar cell transdifferentiation and generation of nestin-positive intermediates

4 September 2018

1 reference

12 December 2020

The mesenchyme controls the timing of pancreatic beta-cell differentiation

1 reference

12 December 2020

Control of beta-cell differentiation by the pancreatic mesenchyme

1 reference

12 December 2020

Fgf10 is essential for maintaining the proliferative capacity of epithelial progenitor cells during early pancreatic organogenesis

1 reference

12 December 2020

Histone deacetylase inhibitors

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12 December 2020

The Pax4 gene is essential for differentiation of insulin-producing β cells in the mammalian pancreas

1 reference

12 December 2020

Identifiers

DOI

10.1128/MCB.00413-08

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18710955%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18710955%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

1 reference