Mitochondrial iPLA2 activity modulates the release of cytochrome c from mitochondria and influences the permeability transition. (Q51289590)

2 April 2018

title

Mitochondrial iPLA2 activity modulates the release of cytochrome c from mitochondria and influences the permeability transition. (English)

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2 April 2018

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Martha E Gadd

1

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2 April 2018

Kimberly M Broekemeier

2

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2 April 2018

Elliott D Crouser

3

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2 April 2018

Jitendra Kumar

4

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2 April 2018

Gustav Graff

5

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2 April 2018

Douglas R Pfeiffer

6

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2 April 2018

language of work or name

English

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publication date

2 January 2006

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2 April 2018

Journal of Biological Chemistry

published in

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2 April 2018

volume

281

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2 April 2018

page(s)

6931-6939

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2 April 2018

issue

11

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2 April 2018

Pore formation and uncoupling initiate a Ca2+-independent degradation of mitochondrial phospholipids

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Inhibition of mitochondrial calcium-independent phospholipase A2 (iPLA2) attenuates mitochondrial phospholipid loss and is cardioprotective

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Inhibition of macrophage Ca(2+)-independent phospholipase A2 by bromoenol lactone and trifluoromethyl ketones.

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Inhibition of the mitochondrial permeability transition by cyclosporin A during long time frame experiments: relationship between pore opening and the activity of mitochondrial phospholipases.

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Recent progress on regulation of the mitochondrial permeability transition pore; a cyclosporin-sensitive pore in the inner mitochondrial membrane

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Mitochondria and cell death.

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The mitochondrial permeability transition pore and its role in cell death

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Quantitation of cytochrome c release from rat liver mitochondria

21 January 2018

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High-pressure liquid chromatography quantitation of cytochrome c using 393 nm detection

21 January 2018

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On the voltage dependence of the mitochondrial permeability transition pore. A critical appraisal.

21 January 2018

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Modulation of the mitochondrial permeability transition pore by pyridine nucleotides and dithiol oxidation at two separate sites.

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Modification of permeability transition pore arginine(s) by phenylglyoxal derivatives in isolated mitochondria and mammalian cells. Structure-function relationship of arginine ligands.

21 January 2018

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Ligand-selective modulation of the permeability transition pore by arginine modification. Opposing effects of p-hydroxyphenylglyoxal and phenylglyoxal.

21 January 2018

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A Ca2+-induced mitochondrial permeability transition causes complete release of rat liver endonuclease G activity from its exclusive location within the mitochondrial intermembrane space. Identification of a novel endo-exonuclease activity residing

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The course of etoposide-induced apoptosis from damage to DNA and p53 activation to mitochondrial release of cytochrome c

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The cytotoxicity of tumor necrosis factor depends on induction of the mitochondrial permeability transition

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Bcl-2 and Bcl-xL inhibit CD95-mediated apoptosis by preventing mitochondrial release of Smac/DIABLO and subsequent inactivation of X-linked inhibitor-of-apoptosis protein

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Cytochrome c release upon Fas receptor activation depends on translocation of full-length bid and the induction of the mitochondrial permeability transition

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Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition

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Endonuclease G is an apoptotic DNase when released from mitochondria

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Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c

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Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins

21 January 2018

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Export of mitochondrial AIF in response to proapoptotic stimuli depends on processing at the intermembrane space

21 January 2018

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Regulated and unregulated mitochondrial permeability transition pores: a new paradigm of pore structure and function?

21 January 2018

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Arachidonic acid released by phospholipase A(2) activation triggers Ca(2+)-dependent apoptosis through the mitochondrial pathway

21 January 2018

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The Ca2+-induced membrane transition in mitochondria. I. The protective mechanisms

21 January 2018

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Selective inhibition of the mitochondrial permeability transition pore at the oxidation-reduction sensitive dithiol by monobromobimane

21 January 2018

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Regulation of the permeability transition pore, a voltage-dependent mitochondrial channel inhibited by cyclosporin A

21 January 2018

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Chemical Modification of Arginines by 2,3-Butanedione and Phenylglyoxal Causes Closure of the Mitochondrial Permeability Transition Pore

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M510845200

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2 April 2018

PubMed ID

16407316

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2 April 2018