Cyclin-dependent kinase inhibitor Roscovitine induces apoptosis in chronic lymphocytic leukemia cells. (Q51028667)

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23 November 2019

title

Cyclin-dependent kinase inhibitor Roscovitine induces apoptosis in chronic lymphocytic leukemia cells (English)

1 reference

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23 November 2019

0 references

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chronic lymphocytic leukemia

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5

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23 November 2019

author name string

I N Hahntow

1

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23 November 2019

F Schneller

2

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23 November 2019

M Oelsner

3

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23 November 2019

K Weick

4

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23 November 2019

F Fend

6

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23 November 2019

C Peschel

7

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23 November 2019

T Decker

8

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23 November 2019

publication date

1 April 2004

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23 November 2019

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23 November 2019

volume

18

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23 November 2019

page(s)

747-755

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23 November 2019

issue

4

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https://scigraph.springernature.com/pub.10.1038/sj.leu.2403295

23 November 2019

exact match

0 references

cites work

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Redefining the therapeutic goals in chronic lymphocytic leukemia: towards an evidence-based, risk-adapted therapy

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Autologous and allogeneic stem cell transplantation for chronic lymphocytic leukemia

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Bcl-2 and apoptosis in chronic lymphocytic leukemia

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The triterpenoid CDDO induces apoptosis in refractory CLL B cells

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Apoptotic-regulatory and complement-protecting protein expression in chronic lymphocytic leukemia: relationship to in vivo rituximab resistance.

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Relation of gene expression phenotype to immunoglobulin mutation genotype in B cell chronic lymphocytic leukemia

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ZAP-70 expression as a surrogate for immunoglobulin-variable-region mutations in chronic lymphocytic leukemia.

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Biochemical and cellular effects of roscovitine, a potent and selective inhibitor of the cyclin-dependent kinases cdc2, cdk2 and cdk5.

21 January 2018

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Cdk inhibitors, roscovitine and olomoucine, synergize with farnesyltransferase inhibitor (FTI) to induce efficient apoptosis of human cancer cell lines

21 January 2018

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The specificities of protein kinase inhibitors: an update

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Potent inhibitors of cyclin-dependent kinase 2 induce nuclear accumulation of wild-type p53 and nucleolar fragmentation in human untransformed and tumor-derived cells

21 January 2018

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Cycling B-CLL cells are highly susceptible to inhibition of the proteasome: involvement of p27, early D-type cyclins, Bax, and caspase-dependent and -independent pathways

21 January 2018

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Lipopolysaccharide-mediated transcriptional activation of the human tissue factor gene in THP-1 monocytic cells requires both activator protein 1 and nuclear factor kappa B binding sites

21 January 2018

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p53 Mutations in nasal natural killer/T-cell lymphoma from Mexico: association with large cell morphology and advanced disease

21 January 2018

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Rapamycin-induced G1 arrest in cycling B-CLL cells is associated with reduced expression of cyclin D3, cyclin E, cyclin A, and survivin

21 January 2018

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Cellular stress response and apoptosis in cancer therapy.

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Complement-mediated cell death induced by rituximab in B-cell lymphoproliferative disorders is mediated in vitro by a caspase-independent mechanism involving the generation of reactive oxygen species

21 January 2018

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The Bcl2 family: regulators of the cellular life-or-death switch

21 January 2018

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Cleavage of Bax enhances its cell death function

21 January 2018

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Cell damage-induced conformational changes of the pro-apoptotic protein Bak in vivo precede the onset of apoptosis

21 January 2018

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Conformational change and mitochondrial translocation of Bax accompany proteasome inhibitor-induced apoptosis of chronic lymphocytic leukemic cells.

21 January 2018

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Spontaneous and drug-induced apoptosis is mediated by conformational changes of Bax and Bak in B-cell chronic lymphocytic leukemia

21 January 2018

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CDK inhibitors in clinical development for the treatment of cancer

21 January 2018

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Survivin is expressed on CD40 stimulation and interfaces proliferation and apoptosis in B-cell chronic lymphocytic leukemia

21 January 2018

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In vitro and in vivo antitumor properties of the cyclin dependent kinase inhibitor CYC202 (R-roscovitine)

21 January 2018

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inferred from DOI database lookup

7 January 2021

based on heuristic

Caspases influence the mode but not the extent of cell death induced by purine analogues in chronic lymphocytic leukaemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403295

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/SJ.LEU.2403295

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14973497%20AND%20SRC:MED&resulttype=core&format=json

23 November 2019

1 reference