Passive immunization with Tau oligomer monoclonal antibody reverses tauopathy phenotypes without affecting hyperphosphorylated neurofibrillary tangles. (Q50856591)

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scientific article published in March 2014

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English	Passive immunization with Tau oligomer monoclonal antibody reverses tauopathy phenotypes without affecting hyperphosphorylated neurofibrillary tangles.	scientific article published in March 2014

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scholarly article

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11 March 2020

Passive immunization with Tau oligomer monoclonal antibody reverses tauopathy phenotypes without affecting hyperphosphorylated neurofibrillary tangles (English)

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11 March 2020

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passive immunization

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monoclonal antibody

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Diana L Castillo-Carranza

1

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11 March 2020

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Urmi Sengupta

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11 March 2020

Marcos J Guerrero-Muñoz

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Cristian A Lasagna-Reeves

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Julia E Gerson

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Gurpreet Singh

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D Mark Estes

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Kelly T Dineley

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George R Jackson

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Rakez Kayed

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Alan D T Barrett

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1 March 2014

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Journal of Neuroscience

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11 June 2022

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Neurons may live for decades with neurofibrillary tangles.

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Characterization of prefibrillar Tau oligomers in vitro and in Alzheimer disease.

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1 reference

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Are tangles as toxic as they look?

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Passive immunization targeting pathological phospho-tau protein in a mouse model reduces functional decline and clears tau aggregates from the brain

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1 reference

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based on heuristic

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1 reference

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1 reference

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based on heuristic

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1 reference

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based on heuristic

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1 reference

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based on heuristic

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Trans-cellular propagation of Tau aggregation by fibrillar species

1 reference

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based on heuristic

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1 reference

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based on heuristic

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1 reference

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12 December 2020

based on heuristic

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The synaptic accumulation of hyperphosphorylated tau oligomers in Alzheimer disease is associated with dysfunction of the ubiquitin-proteasome system

1 reference

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based on heuristic

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1 reference

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based on heuristic

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based on heuristic

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Small misfolded Tau species are internalized via bulk endocytosis and anterogradely and retrogradely transported in neurons

1 reference

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1 reference

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based on heuristic

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1 reference

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1 reference

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1 reference

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based on heuristic

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Formation and propagation of tau oligomeric seeds

1 reference

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1 reference

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based on heuristic

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1 reference

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based on heuristic

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Tau oligomers as potential targets for Alzheimer's diagnosis and novel drugs

1 reference

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based on heuristic

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Immunotherapy for the treatment of Alzheimer's disease: amyloid-β or tau, which is the right target?

1 reference

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based on heuristic

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Neuronal loss correlates with but exceeds neurofibrillary tangles in Alzheimer's disease.

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Identifiers

10.1523/JNEUROSCI.3192-13.2014

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11 March 2020

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11 March 2020

1 reference

Europe PubMed Central

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11 March 2020

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