Immunotherapy targeting pathological tau protein in Alzheimer's disease and related tauopathies. (Q37308949)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18953105%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

review article

1 reference

title

Immunotherapy targeting pathological tau protein in Alzheimer's disease and related tauopathies (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18953105%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

0 references

1 reference

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18953105%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

author name string

Einar M Sigurdsson

series ordinal

1

1 reference

19 August 2017

language of work or name

1 reference

1 October 2008

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18953105%20AND%20SRC:MED&resulttype=core&format=json

Journal of Alzheimer's Disease

25 December 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18953105%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

volume

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18953105%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

page(s)

157-168

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25 December 2019

issue

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18953105%20AND%20SRC:MED&resulttype=core&format=json

Knock-out and transgenic mouse models of tauopathies.

25 December 2019

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26 June 2018

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26 June 2018

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26 June 2018

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26 June 2018

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26 June 2018

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26 June 2018

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26 June 2018

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26 June 2018

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26 June 2018

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2 September 2018

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2 September 2018

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2 September 2018

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2 September 2018

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Accelerated amyloid deposition, neurofibrillary degeneration and neuronal loss in double mutant APP/tau transgenic mice.

2 September 2018

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Effects of alpha-synuclein immunization in a mouse model of Parkinson's disease

2 September 2018

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Cell-cycle reentry and cell death in transgenic mice expressing nonmutant human tau isoforms.

2 September 2018

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Protein conformation significantly influences immune responses to prion protein.

2 September 2018

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757121

Abeta vaccination effects on plaque pathology in the absence of encephalitis in Alzheimer disease

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757121

Development of a safe oral Abeta vaccine using recombinant adeno-associated virus vector for Alzheimer's disease.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757121

{beta}-Amyloid-induced neurodegeneration and protection by structurally diverse microtubule-stabilizing agents.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757121

Method for measurement of the blood-brain barrier permeability in the perfused mouse brain: application to amyloid-beta peptide in wild type and Alzheimer's Tg2576 mice

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757121

EFRH-phage immunization of Alzheimer's disease animal model improves behavioral performance in Morris water maze trials.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757121

Abeta immunotherapy leads to clearance of early, but not late, hyperphosphorylated tau aggregates via the proteasome

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757121

Ultrastructural neuronal pathology in transgenic mice expressing mutant (P301L) human tau.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757121

Neuropathology and pathogenesis of encephalitis following amyloid-beta immunization in Alzheimer's disease.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757121

Passive transfer of purified IgG from patients with amyotrophic lateral sclerosis to mice results in degeneration of motor neurons accompanied by Ca 2+ enhancement

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757121

Evidence for peripheral clearance of cerebral Abeta protein following chronic, active Abeta immunization in PSAPP mice.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757121

Hyperphosphorylation and aggregation of tau in mice expressing normal human tau isoforms.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757121

Antibodies against beta-amyloid slow cognitive decline in Alzheimer's disease.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757121

Neuropathology of human Alzheimer disease after immunization with amyloid-beta peptide: a case report.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757121

Vaccination with amyloid-beta peptide induces autoimmune encephalomyelitis in C57/BL6 mice.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757121

Passage of amyloid beta protein antibody across the blood-brain barrier in a mouse model of Alzheimer's disease.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757121

Generation of antibodies specific for beta-amyloid by vaccination of patients with Alzheimer disease.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757121

Non-Fc-mediated mechanisms are involved in clearance of amyloid-beta in vivo by immunotherapy.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757121

Nonoverlapping but synergetic tau and APP pathologies in sporadic Alzheimer's disease.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757121

Immunoglobulin Fc gamma receptor promotes immunoglobulin uptake, immunoglobulin-mediated calcium increase, and neurotransmitter release in motor neurons

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757121

Formation of neurofibrillary tangles in P301l tau transgenic mice induced by Abeta 42 fibrils

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757121

A beta peptide vaccination prevents memory loss in an animal model of Alzheimer's disease.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757121

Behavioral disturbances in transgenic mice overexpressing the V717F beta-amyloid precursor protein.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757121

Antigen-dependent intrathecal antibody synthesis in the normal rat brain: tissue entry and local retention of antigen-specific B cells.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757121

Tau is a candidate gene for chromosome 17 frontotemporal dementia

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757121

Quantitative analysis of tau protein-immunoreactive accumulations and beta amyloid protein deposits in the cerebral cortex of the mouse lemur, Microcebus murinus.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757121

Serum proteins bypass the blood-brain fluid barriers for extracellular entry to the central nervous system.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757121

Immunocytochemical localization of immunoglobulins in the rat brain: relationship to the blood-brain barrier

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757121

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757121

Plaques, tangles and dementia. A quantitative study.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757121

Internalization of plasma proteins by cerebellar Purkinje cells.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757121

Evaluation of the safety and immunogenicity of synthetic A 42 (AN1792) in patients with AD

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757121

Anti-MAG IgM penetration into myelinated fibers correlates with the extent of myelin widening

3 December 2018

1 reference

12 December 2020

Novel protein transfection of primary rat cortical neurons using an antibody that penetrates living cells

1 reference

12 December 2020

Amyloid-beta immunization effectively reduces amyloid deposition in FcRgamma-/- knock-out mice

1 reference

12 December 2020

Monoclonal antibodies inhibit prion replication and delay the development of prion disease

1 reference

12 December 2020

Direct action of immunoglobulin G on primary sensory neurons through Fc gamma receptor I

1 reference

12 December 2020

Anti-prion antibodies for prophylaxis following prion exposure in mice

1 reference

12 December 2020

Microfilament-associated growth cone component depends upon Tau for its intracellular localization

1 reference

12 December 2020

Phosphorylation of tau alters its association with the plasma membrane

1 reference

12 December 2020

A$beta;1-15 is less immunogenic than A$beta;1-40/42 for intranasal immunization of wild-type mice but may be effective for ?boosting?

1 reference

12 December 2020

Immunohistochemical Analysis of Cerebral Cortical and Vascular Lesions in the Primate Microcebus murinus Reveal Distinct Amyloid β1–42 and β1–40 Immunoreactivity Profiles

1 reference

12 December 2020

Nuclear localization of anti-Hu antibody is not associated with in vitro cytotoxicity

1 reference

12 December 2020

FTDP-17 mutations in tau transgenic mice provoke lysosomal abnormalities and Tau filaments in forebrain

1 reference

12 December 2020

1 reference

12 December 2020

Uptake of systemically administered human anticerebellar antibody by rat Purkinje cells following blood-brain barrier disruption

1 reference

12 December 2020

Identifiers

DOI

10.3233/JAD-2008-15202

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18953105%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18953105%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

1 reference