Efficacy and safety of anakinra therapy in pediatric and adult patients with the autoinflammatory Muckle-Wells syndrome. (Q50434769)

13 March 2018

title

Efficacy and safety of anakinra therapy in pediatric and adult patients with the autoinflammatory Muckle-Wells syndrome. (English)

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author name string

Jasmin B Kuemmerle-Deschner

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Ina Koetter

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Helmut Wittkowski

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Anja Bialkowski

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Nicolai Tzaribachev

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Peter Lohse

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Assen Koitchev

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Christoph Deuter

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Dirk Foell

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Susanne M Benseler

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publication date

1 March 2011

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published in

Arthritis & Rheumatology

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volume

63

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issue

3

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page(s)

840-849

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Familial autoinflammatory diseases: genetics, pathogenesis and treatment

cites work

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De novo CIAS1 mutations, cytokine activation, and evidence for genetic heterogeneity in patients with neonatal-onset multisystem inflammatory disease (NOMID): a new member of the expanding family of pyrin-associated autoinflammatory diseases

21 January 2018

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Spectrum of clinical features in Muckle-Wells syndrome and response to anakinra

21 January 2018

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Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3

21 January 2018

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Cryopyrin activates the inflammasome in response to toxins and ATP

21 January 2018

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Gout-associated uric acid crystals activate the NALP3 inflammasome

21 January 2018

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Critical role for NALP3/CIAS1/Cryopyrin in innate and adaptive immunity through its regulation of caspase-1

21 January 2018

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NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder

21 January 2018

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Risk factors for severe Muckle-Wells syndrome.

21 January 2018

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Neutrophil derived human S100A12 (EN-RAGE) is strongly expressed during chronic active inflammatory bowel disease

21 January 2018

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Evaluation of systemic amyloidosis by scintigraphy with 123I-labeled serum amyloid P component

21 January 2018

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Phenotype, genotype, and sustained response to anakinra in 22 patients with autoinflammatory disease associated with CIAS-1/NALP3 mutations

21 January 2018

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Prevention of cold-associated acute inflammation in familial cold autoinflammatory syndrome by interleukin-1 receptor antagonist

21 January 2018

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Neonatal-onset multisystem inflammatory disease responsive to interleukin-1beta inhibition

21 January 2018

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New CIAS1 mutation and anakinra efficacy in overlapping of Muckle-Wells and familial cold autoinflammatory syndromes

21 January 2018

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A variant Muckle-Wells syndrome with a novel mutation in CIAS1 gene responding to anakinra.

21 January 2018

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Recovery from deafness in a patient with Muckle-Wells syndrome treated with anakinra.

21 January 2018

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Anakinra improves sensory deafness in a Japanese patient with Muckle-Wells syndrome, possibly by inhibiting the cryopyrin inflammasome

21 January 2018

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Hearing improvement in a patient with variant Muckle-Wells syndrome in response to interleukin 1 receptor antagonism

21 January 2018

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Interleukin-1 blockade by anakinra improves clinical symptoms in patients with neonatal-onset multisystem inflammatory disease

21 January 2018

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Mechanisms of disease: a 'DAMP' view of inflammatory arthritis

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/ART.30149

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13 March 2018

PubMed ID

21360513

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13 March 2018