Fragile X mental retardation protein (FMRP) binds specifically to the brain cytoplasmic RNAs BC1/BC200 via a novel RNA-binding motif. (Q48813739)

15 February 2018

title

Fragile X mental retardation protein (FMRP) binds specifically to the brain cytoplasmic RNAs BC1/BC200 via a novel RNA-binding motif. (English)

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15 February 2018

author

Claudia Bagni

8

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Annalisa Pastore

7

object named as

Annalisa Pastore

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15 February 2018

Salvatore Adinolfi

2

object named as

Salvatore Adinolfi

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Francesca Zalfa

object named as

Francesca Zalfa

1

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author name string

Ilaria Napoli

3

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15 February 2018

Eva Kühn-Hölsken

4

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15 February 2018

Henning Urlaub

5

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Tilmann Achsel

6

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language of work or name

English

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publication date

8 July 2005

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15 February 2018

Journal of Biological Chemistry

published in

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15 February 2018

volume

280

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15 February 2018

page(s)

33403-33410

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issue

39

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15 February 2018

Compartmentalized synthesis and degradation of proteins in neurons.

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Evidence that fragile X mental retardation protein is a negative regulator of translation

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The fragile X mental retardation protein inhibits translation via interacting with mRNA

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Drosophila fragile X-related gene regulates the MAP1B homolog Futsch to control synaptic structure and function

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Trapping of messenger RNA by Fragile X Mental Retardation protein into cytoplasmic granules induces translation repression

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The fragile X syndrome protein FMRP associates with BC1 RNA and regulates the translation of specific mRNAs at synapses

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The fragile X protein controls microtubule-associated protein 1B translation and microtubule stability in brain neuron development.

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Fragile X mental retardation protein is associated with translating polyribosomes in neuronal cells.

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Different targets for the fragile X-related proteins revealed by their distinct nuclear localizations

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Metabotropic glutamate receptor activation regulates fragile x mental retardation protein and FMR1 mRNA localization differentially in dendrites and at synapses

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Kinesin transports RNA: isolation and characterization of an RNA-transporting granule

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Microarray identification of FMRP-associated brain mRNAs and altered mRNA translational profiles in fragile X syndrome

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Fragile X mental retardation protein targets G quartet mRNAs important for neuronal function

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RNA cargoes associating with FMRP reveal deficits in cellular functioning in Fmr1 null mice.

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The fragile X mental retardation protein binds and regulates a novel class of mRNAs containing U rich target sequences

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The fragile X mental retardation protein binds specifically to its mRNA via a purine quartet motif

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G-quartet-dependent recognition between the FMRP RGG box and RNA.

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Poly(A)-binding protein is associated with neuronal BC1 and BC200 ribonucleoprotein particles.

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A Drosophila fragile X protein interacts with components of RNAi and ribosomal proteins

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Biochemical and genetic interaction between the fragile X mental retardation protein and the microRNA pathway

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The N-terminus of the fragile X mental retardation protein contains a novel domain involved in dimerization and RNA binding.

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BC200 RNA: a neural RNA polymerase III product encoded by a monomeric Alu element

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Prospects of TAT-mediated protein therapy for fragile X syndrome.

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Identification and characterization of BC1 RNP particles

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The fragile X mental retardation protein has nucleic acid chaperone properties

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The protein product of the fragile X gene, FMR1, has characteristics of an RNA-binding protein

21 January 2018

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Facilitation of dendritic mRNA transport by CPEB

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The Tudor domain 'Royal Family': Tudor, plant Agenet, Chromo, PWWP and MBT domains

21 January 2018

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Characterization and localization of the FMR-1 gene product associated with fragile X syndrome

21 January 2018

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Shared protein components of SINE RNPs

21 January 2018

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Kissing complex RNAs mediate interaction between the Fragile-X mental retardation protein KH2 domain and brain polyribosomes

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M504286200

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15 February 2018

PubMed ID

16006558

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15 February 2018