Microarray identification of FMRP-associated brain mRNAs and altered mRNA translational profiles in fragile X syndrome (Q29616495)

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Brown V

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Jin P

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Ceman S

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Darnell JC

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O'Donnell WT

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Tenenbaum SA

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Jin X

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Feng Y

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Wilkinson KD

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Keene JD

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Darnell RB

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Warren ST

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language of work or name

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30 April 2017

publication date

16 November 2001

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volume

107

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issue

4

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page(s)

477-87

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Drosophila UNC-13 is essential for synaptic transmission

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FMR1 protein: conserved RNP family domains and selective RNA binding

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The cerebellum-specific Munc13 isoform Munc13-3 regulates cerebellar synaptic transmission and motor learning in mice

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A novel RNA-binding nuclear protein that interacts with the fragile X mental retardation (FMR1) protein

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Purified recombinant Fmrp exhibits selective RNA binding as an intrinsic property of the fragile X mental retardation protein

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Intrinsic neuronal determinants that promote axonal sprouting and elongation

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Isolation of an FMRP-associated messenger ribonucleoprotein particle and identification of nucleolin and the fragile X-related proteins as components of the complex

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Identification of mouse YB1/p50 as a component of the FMRP-associated mRNP particle

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Fragile X mental retardation protein targets G quartet mRNAs important for neuronal function

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A point mutation in the FMR-1 gene associated with fragile X mental retardation

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The fragile X mental retardation protein is a ribonucleoprotein containing both nuclear localization and nuclear export signals

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Neuronal abnormalities in microtubule-associated protein 1B mutant mice

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Cluster analysis and display of genome-wide expression patterns

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FMRP associates with polyribosomes as an mRNP, and the I304N mutation of severe fragile X syndrome abolishes this association

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Fragile X mental retardation protein: nucleocytoplasmic shuttling and association with somatodendritic ribosomes

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Shared and unique roles of CAP23 and GAP43 in actin regulation, neurite outgrowth, and anatomical plasticity

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Analysis of neocortex in three males with the fragile X syndrome

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Distinct regional distribution in the brain of messenger RNAs for the two isoforms of synaphin associated with the docking/fusion complex

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Ribonucleoprotein infrastructure regulating the flow of genetic information between the genome and the proteome

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The fragile X mental retardation protein is associated with ribosomes

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Evidence that fragile X mental retardation protein is a negative regulator of translation

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The fragile X mental retardation protein inhibits translation via interacting with mRNA

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Controlling small guanine-nucleotide-exchange factor function through cytoplasmic RNA intramers

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Neuritin: a gene induced by neural activity and neurotrophins that promotes neuritogenesis

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Direct interaction between the ARF-specific guanine nucleotide exchange factor msec7-1 and presynaptic Munc13-1.

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Abnormal development of dendritic spines in FMR1 knock-out mice

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Instability of a 550-base pair DNA segment and abnormal methylation in fragile X syndrome

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A highly conserved protein family interacting with the fragile X mental retardation protein (FMRP) and displaying selective interactions with FMRP-related proteins FXR1P and FXR2P

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Essential role for KH domains in RNA binding: impaired RNA binding by a mutation in the KH domain of FMR1 that causes fragile X syndrome

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The protein product of the fragile X gene, FMR1, has characteristics of an RNA-binding protein

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Identification of a gene (FMR-1) containing a CGG repeat coincident with a breakpoint cluster region exhibiting length variation in fragile X syndrome

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Fragile X mental retardation protein is translated near synapses in response to neurotransmitter activation

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