Gα(olf) mutation allows parsing the role of cAMP-dependent and extracellular signal-regulated kinase-dependent signaling in L-3,4-dihydroxyphenylalanine-induced dyskinesia. (Q48545028)

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English	Gα(olf) mutation allows parsing the role of cAMP-dependent and extracellular signal-regulated kinase-dependent signaling in L-3,4-dihydroxyphenylalanine-induced dyskinesia.	scientific article

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12 February 2018

http://europepmc.org/abstract/MED/22539851

Gα(olf) mutation allows parsing the role of cAMP-dependent and extracellular signal-regulated kinase-dependent signaling in L-3,4-dihydroxyphenylalanine-induced dyskinesia (English)

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11 May 2020

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Jean-Antoine Girault

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11 May 2020

Cristina Alcacer

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11 May 2020

Emmanuel Valjent

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11 May 2020

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Denis Hervé

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11 May 2020

Emanuela Santini

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Emanuela Santini

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11 May 2020

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Florence Gaven

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11 May 2020

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1 April 2012

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12 February 2018

http://europepmc.org/abstract/MED/22539851

Journal of Neuroscience

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11 May 2020

32

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11 May 2020

5900-5910

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11 May 2020

Chronic D1 and D2 dopaminomimetic treatment of MPTP-denervated monkeys: effects on basal ganglia GABA(A)/benzodiazepine receptor complex and GABA content.

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https://pubmed.ncbi.nlm.nih.gov/22539851

12 December 2020

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Regulation of the phosphorylation of the dopamine- and cAMP-regulated phosphoprotein of 32 kDa in vivo by dopamine D1, dopamine D2, and adenosine A2A receptors

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https://pubmed.ncbi.nlm.nih.gov/22539851

12 December 2020

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Medical treatment of levodopa-induced dyskinesias.

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https://pubmed.ncbi.nlm.nih.gov/22539851

12 December 2020

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Regulation of phosphorylation of the GluR1 AMPA receptor in the neostriatum by dopamine and psychostimulants in vivo

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https://pubmed.ncbi.nlm.nih.gov/22539851

12 December 2020

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G(olf)alpha mediates dopamine D1 receptor signaling.

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https://pubmed.ncbi.nlm.nih.gov/22539851

12 December 2020

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Adenosine A(2A) receptors are colocalized with and activate g(olf) in rat striatum

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https://pubmed.ncbi.nlm.nih.gov/22539851

12 December 2020

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Induction by dopamine D1 receptor agonist ABT-431 of dyskinesia similar to levodopa in patients with Parkinson disease

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https://pubmed.ncbi.nlm.nih.gov/22539851

12 December 2020

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Galpha(olf) is necessary for coupling D1 and A2a receptors to adenylyl cyclase in the striatum

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https://pubmed.ncbi.nlm.nih.gov/22539851

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dopamine D(1) receptor expression in human basal ganglia and changes in Parkinson's disease

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https://pubmed.ncbi.nlm.nih.gov/22539851

12 December 2020

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Galpha(olf) levels are regulated by receptor usage and control dopamine and adenosine action in the striatum

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https://pubmed.ncbi.nlm.nih.gov/22539851

12 December 2020

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Pharmacological validation of behavioural measures of akinesia and dyskinesia in a rat model of Parkinson's disease.

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https://pubmed.ncbi.nlm.nih.gov/22539851

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

D1 dopamine receptor supersensitivity in the dopamine-depleted striatum results from a switch in the regulation of ERK1/2/MAP kinase.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22539851

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Loss of G protein gamma 7 alters behavior and reduces striatal alpha(olf) level and cAMP production

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https://pubmed.ncbi.nlm.nih.gov/22539851

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of the alpha subunit of Gs in intact cells alters its abundance, rate of degradation, and membrane avidity

1 reference

https://pubmed.ncbi.nlm.nih.gov/22539851

12 December 2020

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Addictive and non-addictive drugs induce distinct and specific patterns of ERK activation in mouse brain.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22539851

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A model of L-DOPA-induced dyskinesia in 6-hydroxydopamine lesioned mice: relation to motor and cellular parameters of nigrostriatal function

1 reference

https://pubmed.ncbi.nlm.nih.gov/22539851

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Persistent increase in olfactory type G-protein alpha subunit levels may underlie D1 receptor functional hypersensitivity in Parkinson disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22539851

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased D1 dopamine receptor signaling in levodopa-induced dyskinesia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22539851

12 December 2020

based on heuristic

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Regulation of a protein phosphatase cascade allows convergent dopamine and glutamate signals to activate ERK in the striatum

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https://pubmed.ncbi.nlm.nih.gov/22539851

12 December 2020

based on heuristic

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Pharmacological validation of a mouse model of l-DOPA-induced dyskinesia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22539851

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ERK phosphorylation and FosB expression are associated with L-DOPA-induced dyskinesia in hemiparkinsonian mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/22539851

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Levodopa-associated dyskinesia risk among Parkinson disease patients in Olmsted County, Minnesota, 1976-1990.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22539851

12 December 2020

based on heuristic

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Enhanced preproenkephalin-B-derived opioid transmission in striatum and subthalamic nucleus converges upon globus pallidus internalis in L-3,4-dihydroxyphenylalanine-induced dyskinesia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22539851

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Development of dyskinesias in a 5-year trial of ropinirole andL-dopa

1 reference

https://pubmed.ncbi.nlm.nih.gov/22539851

12 December 2020

based on heuristic

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Quantitative changes in Galphaolf protein levels, but not D1 receptor, alter specifically acute responses to psychostimulants.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22539851

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Forebrain adenosine A2A receptors contribute to L-3,4-dihydroxyphenylalanine-induced dyskinesia in hemiparkinsonian mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22539851

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ca2+ -stimulated adenylyl cyclases regulate ERK-dependent activation of MSK1 during fear conditioning

1 reference

https://pubmed.ncbi.nlm.nih.gov/22539851

12 December 2020

based on heuristic

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Dopamine dysregulation of movement control in L-DOPA-induced dyskinesia

1 reference

https://pubmed.ncbi.nlm.nih.gov/22539851

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Critical involvement of cAMP/DARPP-32 and extracellular signal-regulated protein kinase signaling in L-DOPA-induced dyskinesia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22539851

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Spatiotemporal pattern of striatal ERK1/2 phosphorylation in a rat model of L-DOPA-induced dyskinesia and the role of dopamine D1 receptors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22539851

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Parkinson's disease: levodopa-induced dyskinesia and signal transduction.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22539851

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Striatal histone modifications in models of levodopa-induced dyskinesia

1 reference

https://pubmed.ncbi.nlm.nih.gov/22539851

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Behavioral and biochemical correlates of the dyskinetic potential of dopaminergic agonists in the 6-OHDA lesioned rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22539851

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differences between dorsal and ventral striatum in Drd1a dopamine receptor coupling of dopamine- and cAMP-regulated phosphoprotein-32 to activation of extracellular signal-regulated kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/22539851

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular mechanisms of L-DOPA-induced dyskinesia

1 reference

https://pubmed.ncbi.nlm.nih.gov/22539851

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

L-DOPA activates ERK signaling and phosphorylates histone H3 in the striatonigral medium spiny neurons of hemiparkinsonian mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/22539851

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacological modulation of glutamate transmission in a rat model of L-DOPA-induced dyskinesia: effects on motor behavior and striatal nuclear signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/22539851

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacological analysis demonstrates dramatic alteration of D1 dopamine receptor neuronal distribution in the rat analog of L-DOPA-induced dyskinesia

1 reference

https://pubmed.ncbi.nlm.nih.gov/22539851

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dopamine depletion induces distinct compensatory gene expression changes in DARPP-32 signal transduction cascades of striatonigral and striatopallidal neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/22539851

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic inactivation of dopamine D1 but not D2 receptors inhibits L-DOPA-induced dyskinesia and histone activation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22539851

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of mTOR signaling in Parkinson's disease prevents L-DOPA-induced dyskinesia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22539851

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

G(olf) in the basal ganglia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22539851

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Striatal inhibition of PKA prevents levodopa-induced behavioural and molecular changes in the hemiparkinsonian rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22539851

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adenosine A2A receptor signaling and golf assembly show a specific requirement for the gamma7 subtype in the striatum

1 reference

https://pubmed.ncbi.nlm.nih.gov/22539851

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distinct subclasses of medium spiny neurons differentially regulate striatal motor behaviors

1 reference

https://pubmed.ncbi.nlm.nih.gov/22539851

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Maladaptive striatal plasticity in L-DOPA-induced dyskinesia

1 reference

https://pubmed.ncbi.nlm.nih.gov/22539851

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

L-DOPA-induced dyskinesia in hemiparkinsonian rats is associated with up-regulation of adenylyl cyclase type V/VI and increased GABA release in the substantia nigra reticulata

1 reference

https://pubmed.ncbi.nlm.nih.gov/22539851

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distinct changes in cAMP and extracellular signal-regulated protein kinase signalling in L-DOPA-induced dyskinesia

1 reference

https://pubmed.ncbi.nlm.nih.gov/22539851

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Levodopa-induced dyskinesias in patients with Parkinson's disease: filling the bench-to-bedside gap.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22539851

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclic adenosine monophosphate-independent tyrosine phosphorylation of NR2B mediates cocaine-induced extracellular signal-regulated kinase activation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22539851

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of Ras-guanine nucleotide-releasing factor 1 (Ras-GRF1) signaling in the striatum reverts motor symptoms associated with L-dopa-induced dyskinesia

1 reference

https://pubmed.ncbi.nlm.nih.gov/22539851

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhanced striatal cholinergic neuronal activity mediates L-DOPA-induced dyskinesia in parkinsonian mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/22539851

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impact of the lesion procedure on the profiles of motor impairment and molecular responsiveness to L-DOPA in the 6-hydroxydopamine mouse model of Parkinson's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22539851

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of striatal projection systems by dopamine

1 reference

https://pubmed.ncbi.nlm.nih.gov/22539851

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Striatal Signaling in L-DOPA-Induced Dyskinesia: Common Mechanisms with Drug Abuse and Long Term Memory Involving D1 Dopamine Receptor Stimulation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22539851

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

L-DOPA-Induced Dyskinesia and Abnormal Signaling in Striatal Medium Spiny Neurons: Focus on Dopamine D1 Receptor-Mediated Transmission

1 reference

https://pubmed.ncbi.nlm.nih.gov/22539851

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Different plasticity changes in D1 and D2 receptors in rat striatal subregions following impairment of dopaminergic transmission.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22539851

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Striatal phosphoproteins in Parkinson disease and progressive supranuclear palsy

1 reference

https://pubmed.ncbi.nlm.nih.gov/22539851

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications

1 reference

https://pubmed.ncbi.nlm.nih.gov/22539851

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DARPP-32, a dopamine- and adenosine 3':5'-monophosphate-regulated neuronal phosphoprotein. I. Amino acid sequence around the phosphorylated threonine

1 reference

https://pubmed.ncbi.nlm.nih.gov/22539851

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transmembrane signalling systems in the brain of patients with Parkinson's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22539851

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Striatal G-proteins: effects of unilateral 6-hydroxydopamine lesions.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22539851

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

G(olf) and Gs in rat basal ganglia: possible involvement of G(olf) in the coupling of dopamine D1 receptor with adenylyl cyclase

1 reference

https://pubmed.ncbi.nlm.nih.gov/22539851

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dopamine D1 receptors in Parkinson's disease and striatonigral degeneration: a positron emission tomography study

1 reference

https://pubmed.ncbi.nlm.nih.gov/22539851

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Levels of stimulatory G protein are increased in the rat striatum after neonatal lesion of dopamine neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22539851

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo studies on striatal dopamine D1 and D2 site binding in L-dopa-treated Parkinson's disease patients with and without dyskinesias.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22539851

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mice deficient in G(olf) are anosmic

1 reference

https://pubmed.ncbi.nlm.nih.gov/22539851

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

L-DOPA-induced dyskinesia in the rat is associated with striatal overexpression of prodynorphin- and glutamic acid decarboxylase mRNA.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22539851

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.0837-12.2012

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6703620&resulttype=core&format=json

11 May 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6703620&resulttype=core&format=json

11 May 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6703620&resulttype=core&format=json

11 May 2020

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