A Bax-induced pro-oxidant state is critical for cytochrome c release during programmed neuronal death. (Q48525982)

http://europepmc.org/abstract/MED/12151527

12 February 2018

title

A Bax-induced pro-oxidant state is critical for cytochrome c release during programmed neuronal death (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6758153&resulttype=core&format=json

12 May 2020

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6758153&resulttype=core&format=json

12 May 2020

author name string

Rebecca A Kirkland

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6758153&resulttype=core&format=json

12 May 2020

Julia M Kasprzak

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6758153&resulttype=core&format=json

12 May 2020

James L Franklin

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6758153&resulttype=core&format=json

12 May 2020

language of work or name

English

0 references

publication date

1 August 2002

1 reference

http://europepmc.org/abstract/MED/12151527

12 February 2018

published in

Journal of Neuroscience

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6758153&resulttype=core&format=json

12 May 2020

volume

22

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6758153&resulttype=core&format=json

12 May 2020

issue

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6758153&resulttype=core&format=json

12 May 2020

page(s)

6480-6490

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6758153&resulttype=core&format=json

The release of cytochrome c from mitochondria during apoptosis of NGF-deprived sympathetic neurons is a reversible event

12 May 2020

cites work

1 reference

12 December 2020

Activation of membrane-associated procaspase-3 is regulated by Bcl-2.

1 reference

12 December 2020

BAX translocation is a critical event in neuronal apoptosis: regulation by neuroprotectants, BCL-2, and caspases

1 reference

12 December 2020

Bax oligomerization is required for channel-forming activity in liposomes and to trigger cytochrome c release from mitochondria

1 reference

12 December 2020

Biochemical and genetic analysis of the mitochondrial response of yeast to BAX and BCL-X(L)

1 reference

12 December 2020

Electrophysiological study of a novel large pore formed by Bax and the voltage-dependent anion channel that is permeable to cytochrome c.

1 reference

12 December 2020

Role of oxidative phosphorylation in Bax toxicity.

1 reference

12 December 2020

Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition

1 reference

12 December 2020

Preservation of mitochondrial structure and function after Bid- or Bax-mediated cytochrome c release

1 reference

12 December 2020

Apoptosis in the nervous system

1 reference

12 December 2020

VDAC regulation by the Bcl-2 family of proteins

1 reference

12 December 2020

The role of the Bcl-2 family in the regulation of outer mitochondrial membrane permeability

1 reference

12 December 2020

Evidence for redox regulation of cytochrome C release during programmed neuronal death: antioxidant effects of protein synthesis and caspase inhibition.

1 reference

12 December 2020

Induction of BIM, a proapoptotic BH3-only BCL-2 family member, is critical for neuronal apoptosis

1 reference

12 December 2020

The mitochondrion in apoptosis: how Pandora's box opens

1 reference

12 December 2020

Endonuclease G is an apoptotic DNase when released from mitochondria

1 reference

12 December 2020

A novel, high conductance channel of mitochondria linked to apoptosis in mammalian cells and Bax expression in yeast

1 reference

12 December 2020

VDAC-dependent permeabilization of the outer mitochondrial membrane by superoxide induces rapid and massive cytochrome c release

1 reference

12 December 2020

Cell death during development of the nervous system

1 reference

12 December 2020

The use of monochlorobimane to determine hepatic GSH levels and synthesis

1 reference

12 December 2020

Inhibitors of protein synthesis and RNA synthesis prevent neuronal death caused by nerve growth factor deprivation

1 reference

12 December 2020

Bcl-2 functions in an antioxidant pathway to prevent apoptosis

1 reference

12 December 2020

Temporal analysis of events associated with programmed cell death (apoptosis) of sympathetic neurons deprived of nerve growth factor

1 reference

12 December 2020

Programmed cell death and Bcl-2 protection in very low oxygen.

1 reference

12 December 2020

Bax-deficient mice with lymphoid hyperplasia and male germ cell death

1 reference

12 December 2020

Mutations associated with amyotrophic lateral sclerosis convert superoxide dismutase from an antiapoptotic gene to a proapoptotic gene: studies in yeast and neural cells

1 reference

12 December 2020

Prevention of hypoxia-induced cell death by Bcl-2 and Bcl-xL.

1 reference

12 December 2020

Chronic depolarization prevents programmed death of sympathetic neurons in vitro but does not support growth: requirement for Ca2+ influx but not Trk activation

1 reference

12 December 2020

Superoxide dismutase delays neuronal apoptosis: a role for reactive oxygen species in programmed neuronal death

1 reference

12 December 2020

Macromolecular synthesis inhibitors prevent oxidative stress-induced apoptosis in embryonic cortical neurons by shunting cysteine from protein synthesis to glutathione.

1 reference

12 December 2020

Bcl-2 inhibition of neural death: decreased generation of reactive oxygen species

1 reference

12 December 2020

Evaluation of 2',7'-dichlorofluorescin and dihydrorhodamine 123 as fluorescent probes for intracellular H2O2 in cultured endothelial cells

1 reference

12 December 2020

Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c

1 reference

12 December 2020

Shift of the cellular oxidation-reduction potential in neural cells expressing Bcl-2.

1 reference

12 December 2020

Potassium deprivation-induced apoptosis of cerebellar granule neurons: a sequential requirement for new mRNA and protein synthesis, ICE-like protease activity, and reactive oxygen species.

1 reference

12 December 2020

BAX is required for neuronal death after trophic factor deprivation and during development

1 reference

12 December 2020

Metabolic and genetic analyses of apoptosis in potassium/serum-deprived rat cerebellar granule cells.

1 reference

12 December 2020

Genetic and metabolic status of NGF-deprived sympathetic neurons saved by an inhibitor of ICE family proteases

1 reference

12 December 2020

Insulin-like growth factor and potassium depolarization maintain neuronal survival by distinct pathways: possible involvement of PI 3-kinase in IGF-1 signaling.

1 reference

12 December 2020

Rapid suppression of free radical formation by nerve growth factor involves the mitogen-activated protein kinase pathway

1 reference

12 December 2020

Superoxide production by the mitochondrial respiratory chain

1 reference

12 December 2020

Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3

1 reference

12 December 2020

Bax deletion further orders the cell death pathway in cerebellar granule cells and suggests a caspase-independent pathway to cell death.

1 reference

12 December 2020

Comparison of the ion channel characteristics of proapoptotic BAX and antiapoptotic BCL-2.

1 reference

12 December 2020

Movement of Bax from the cytosol to mitochondria during apoptosis

1 reference

12 December 2020

Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

1 reference

12 December 2020

Analysis of the mechanism of loss of trophic factor dependence associated with neuronal maturation: a phenotype indistinguishable from Bax deletion.

1 reference

12 December 2020

Modulation of cell death by Bcl-XL through caspase interaction

1 reference

12 December 2020

Widespread elimination of naturally occurring neuronal death in Bax-deficient mice

1 reference

12 December 2020

Bcl-2 prolongs cell survival after Bax-induced release of cytochrome c

1 reference

12 December 2020

Superoxide in apoptosis. Mitochondrial generation triggered by cytochrome c loss

1 reference

12 December 2020

The regulation of reactive oxygen species production during programmed cell death

1 reference

12 December 2020

Control of neuronal size homeostasis by trophic factor-mediated coupling of protein degradation to protein synthesis

1 reference

12 December 2020

Blocking cytochrome c activity within intact neurons inhibits apoptosis.

1 reference

12 December 2020

Evidence of a novel event during neuronal death: development of competence-to-die in response to cytoplasmic cytochrome c

1 reference

12 December 2020

Molecular characterization of mitochondrial apoptosis-inducing factor

1 reference

12 December 2020

10.1523/JNEUROSCI.22-15-06480.2002

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6758153&resulttype=core&format=json

12 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6758153&resulttype=core&format=json

12 May 2020

1 reference