N-terminally deleted forms of the prion protein activate both Bax-dependent and Bax-independent neurotoxic pathways. (Q48298632)

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24 December 2019

title

N-terminally deleted forms of the prion protein activate both Bax-dependent and Bax-independent neurotoxic pathways (English)

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24 December 2019

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3

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24 December 2019

David A Harris

series ordinal

4

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24 December 2019

author name string

Aimin Li

series ordinal

1

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24 December 2019

Sami J Barmada

series ordinal

2

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24 December 2019

language of work or name

English

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publication date

1 January 2007

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24 December 2019

published in

Journal of Neuroscience

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24 December 2019

volume

27

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24 December 2019

issue

4

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24 December 2019

page(s)

852-859

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Prions prevent neuronal cell-line death.

24 December 2019

cites work

1 reference

12 December 2020

Ataxia in prion protein (PrP)-deficient mice is associated with upregulation of the novel PrP-like protein doppel

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12 December 2020

Apoptosis in the nervous system

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12 December 2020

Onset of ataxia and Purkinje cell loss in PrP null mice inversely correlated with Dpl level in brain

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12 December 2020

Two different neurodegenerative diseases caused by proteins with similar structures

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12 December 2020

Elimination of Bax expression in mice increases cerebellar purkinje cell numbers but not the number of granule cells

1 reference

12 December 2020

Prion protein protects human neurons against Bax-mediated apoptosis

1 reference

12 December 2020

Doppel-induced cerebellar degeneration in transgenic mice

1 reference

12 December 2020

Small is not beautiful: antagonizing functions for the prion protein PrP(C) and its homologue Dpl.

1 reference

12 December 2020

NMR structure of the human doppel protein

1 reference

12 December 2020

Expression of truncated PrP targeted to Purkinje cells of PrP knockout mice causes Purkinje cell death and ataxia

1 reference

12 December 2020

Cytosolic prion protein is not toxic and protects against Bax-mediated cell death in human primary neurons

1 reference

12 December 2020

Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein

1 reference

12 December 2020

Diversity in the mechanisms of neuronal cell death.

1 reference

12 December 2020

Depleting neuronal PrP in prion infection prevents disease and reverses spongiosis.

1 reference

12 December 2020

Cell death: critical control points

1 reference

12 December 2020

Mammalian prion biology: one century of evolving concepts

1 reference

12 December 2020

Prion protein prevents human breast carcinoma cell line from tumor necrosis factor alpha-induced cell death

1 reference

12 December 2020

Bcl-2 family regulation of neuronal development and neurodegeneration.

1 reference

12 December 2020

Transgene-driven expression of the Doppel protein in Purkinje cells causes Purkinje cell degeneration and motor impairment

1 reference

12 December 2020

Doppel-induced Purkinje cell death is stoichiometrically abrogated by prion protein

1 reference

12 December 2020

Neurons exclusively express N-Bak, a BH3 domain-only Bak isoform that promotes neuronal apoptosis

1 reference

12 December 2020

Bax deletion prevents neuronal loss but not neurological symptoms in a transgenic model of inherited prion disease.

1 reference

12 December 2020

Mammalian prion protein suppresses Bax-induced cell death in yeast

1 reference

12 December 2020

Cellular prion protein inhibits proapoptotic Bax conformational change in human neurons and in breast carcinoma MCF-7 cells

1 reference

12 December 2020

Truncated Prion Protein and Doppel Are Myelinotoxic in the Absence of Oligodendrocytic PrPC

1 reference

12 December 2020

Role of caspase-3 in ethanol-induced developmental neurodegeneration

1 reference

12 December 2020

Anchorless prion protein results in infectious amyloid disease without clinical scrapie

1 reference

12 December 2020

How the Bcl-2 family of proteins interact to regulate apoptosis.

1 reference

12 December 2020

New insights into prion structure and toxicity.

1 reference

12 December 2020

Bax deletion does not protect neurons from BSE-induced death.

1 reference

12 December 2020

Prion protein prevents Bax-mediated cell death in the absence of other Bcl-2 family members in Saccharomyces cerevisiae

1 reference

12 December 2020

Neonatal lethality in transgenic mice expressing prion protein with a deletion of residues 105-125.

1 reference

12 December 2020

Normal host prion protein necessary for scrapie-induced neurotoxicity.

1 reference

12 December 2020

Loss of cerebellar Purkinje cells in aged mice homozygous for a disrupted PrP gene.

1 reference

12 December 2020

BAX is required for neuronal death after trophic factor deprivation and during development

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12 December 2020

Bax deficiency prevents the increased cell death of immature neurons in bcl-x-deficient mice

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12 December 2020

Identification of necrotic cell death by the TUNEL assay in the hypoxic-ischemic neonatal rat brain.

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12 December 2020

Expression of amino-terminally truncated PrP in the mouse leading to ataxia and specific cerebellar lesions.

1 reference

12 December 2020

1 reference

12 December 2020

Neurological illness in transgenic mice expressing a prion protein with an insertional mutation.

1 reference

12 December 2020

10.1523/JNEUROSCI.4244-06.2007

Identifiers

DOI

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24 December 2019

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24 December 2019

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