Lactate metabolism: historical context, prior misinterpretations, and current understanding. (Q48265527)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29322250%20AND%20SRC:MED&resulttype=core&format=json

9 April 2020

title

Lactate metabolism: historical context, prior misinterpretations, and current understanding (English)

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9 April 2020

6

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9 April 2020

author name string

Brian S Ferguson

1

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9 April 2020

Matthew J Rogatzki

2

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9 April 2020

Matthew L Goodwin

3

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9 April 2020

Daniel A Kane

4

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9 April 2020

Zachary Rightmire

5

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9 April 2020

publication date

10 January 2018

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European Journal of Applied Physiology

9 April 2020

published in

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9 April 2020

volume

118

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9 April 2020

page(s)

691-728

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9 April 2020

issue

4

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https://scigraph.springernature.com/pub.10.1007/s00421-017-3795-6

9 April 2020

exact match

0 references

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Early lactate-guided therapy in intensive care unit patients: a multicenter, open-label, randomized controlled trial.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Hydrogen ion balance during exercise

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Monocarboxylate Transporters: Therapeutic Targets and Prognostic Factors in Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Ubiquinone reduction pattern in pigeon heart mitochondria. Identification of three distinct ubiquinone pools

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Current aspects of lactate exchange: lactate/H+ transport in human skeletal muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Lactate transport in skeletal muscle - role and regulation of the monocarboxylate transporter.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Lactate oxidation at the mitochondria: a lactate-malate-aspartate shuttle at work

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Effects of previous exercise with arms or legs on metabolism and performance in exhaustive exercise

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Regulation of lactic acid production during exercise

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Exercise Intensity Thresholds: Identifying the Boundaries of Sustainable Performance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Lactate metabolism in resting and contracting canine skeletal muscle with elevated lactate concentration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Tumor metabolism of lactate: the influence and therapeutic potential for MCT and CD147 regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

HIF-1-mediated expression of pyruvate dehydrogenase kinase: a metabolic switch required for cellular adaptation to hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

The significance of the aerobic-anaerobic transition for the determination of work load intensities during endurance training

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Lactate administration increases mRNA expression of PGC-1α and UCP3 in mouse skeletal muscle.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

The first demonstration of lactic acid in human blood in shock by Johann Joseph Scherer (1814-1869) in January 1843.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Study of GPR81, the lactate receptor, from distant species identifies residues and motifs critical for GPR81 functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Overexpression of Glut-1 and increased glucose metabolism in tumors are associated with a poor prognosis in patients with oral squamous cell carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

A computational model for glycogenolysis in skeletal muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Lactate receptor sites link neurotransmission, neurovascular coupling, and brain energy metabolism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Lactate favours the dissociation of skeletal muscle 6-phosphofructo-1-kinase tetramers down-regulating the enzyme and muscle glycolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Lactate downregulates the glycolytic enzymes hexokinase and phosphofructokinase in diverse tissues from mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Mitochondrial lactate dehydrogenase is involved in oxidative-energy metabolism in human astrocytoma cells (CCF-STTG1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Exercise Inducible Lactate Dehydrogenase B Regulates Mitochondrial Function in Skeletal Muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Inward flux of lactate⁻ through monocarboxylate transporters contributes to regulatory volume increase in mouse muscle fibres

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Lactate inhibits lipolysis in fat cells through activation of an orphan G-protein-coupled receptor, GPR81

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Myocardial fatty acid metabolism in health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Hypoxia is not the sole cause of lactate production during shock

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Aerobic glycolysis: meeting the metabolic requirements of cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Expression and putative role of mitochondrial transport proteins in cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Cellular bases of brain energy metabolism and their relevance to functional brain imaging: evidence for a prominent role of astrocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Lactic acidosis in vivo: testing the link between lactate generation and H+ accumulation in ischemic mouse muscle.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Cancer metabolism: a therapeutic perspective

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Evaluation of AZD1446 as a Therapeutic in DYT1 Dystonia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Adrenergic contribution during acclimatization to high altitude: perspectives from Pikes Peak

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Lactate and glucose interactions during rest and exercise in men: effect of exogenous lactate infusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Metabolic and cardiorespiratory responses to "the lactate clamp".

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Energy metabolism in tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

The lactate receptor, G-protein-coupled receptor 81/hydroxycarboxylic acid receptor 1: Expression and action in brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

A study of metabolites as intermediate effectors in angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Lactate as a Signaling Molecule That Regulates Exercise-Induced Adaptations

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Half-molar sodium lactate infusion improves cardiac performance in acute heart failure: a pilot randomised controlled clinical trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Phosphate and acidosis act synergistically to depress peak power in rat muscle fibers

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Relative hyperlactatemia and hospital mortality in critically ill patients: a retrospective multi-centre study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Indices of lactate threshold and their relationship with 10-km running velocity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Protective effects of lactic acid on force production in rat skeletal muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Attenuated hepatosplanchnic uptake of lactate during intense exercise in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Hypothesis: using the Warburg effect against cancer by reducing glucose and providing lactate

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Visualization of glutamate as a volume transmitter

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Warburg effect(s)-a biographical sketch of Otto Warburg and his impacts on tumor metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Role of cell type in net lactate removal by skeletal muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

The predictive value of initial serum lactate in trauma patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Mitochondria and L-lactate metabolism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

The mitochondrial L-lactate dehydrogenase affair.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

The occurrence of l-lactate dehydrogenase in the inner mitochondrial compartment of pig liver.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

The reverse Warburg effect: aerobic glycolysis in cancer associated fibroblasts and the tumor stroma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Intracellular acidosis enhances the excitability of working muscle.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Lactate as a pivotal element in neuron-glia metabolic cooperation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Food for thought: the importance of glucose and other energy substrates for sustaining brain function under varying levels of activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Glutamate uptake into astrocytes stimulates aerobic glycolysis: a mechanism coupling neuronal activity to glucose utilization

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

How to balance the brain energy budget while spending glucose differently

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

21 January 2018

Sweet sixteen for ANLS.

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Evidence supporting the existence of an activity-dependent astrocyte-neuron lactate shuttle.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Monocarboxylate transporter 4 (MCT4) and CD147 overexpression is associated with poor prognosis in prostate cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Mouse MCT3 gene is expressed preferentially in retinal pigment and choroid plexus epithelia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Predicting lactate threshold using ventilatory threshold

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

A prospective, randomized study of goal-oriented hemodynamic therapy in cardiac surgical patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Mitochondrial tissue specificity of substrates utilization in rat cardiac and skeletal muscles.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Identification and partial purification of the erythrocyte L-lactate transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Transport of lactate and other monocarboxylates across mammalian plasma membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

L(+)-lactate does not affect twitch and tetanic responses in mechanically skinned mammalian muscle fibres

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

The Warburg effect: 80 years on

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

The discovery of oxidative phosphorylation: a conceptual off-shoot from the study of glycolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Maximal lactate steady state, critical power and EMG during cycling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Lactate as a Metabolite and a Regulator in the Central Nervous System

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Improvement of Neuroenergetics by Hypertonic Lactate Therapy in Patients with Traumatic Brain Injury Is Dependent on Baseline Cerebral Lactate/Pyruvate Ratio

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Lactate fuels the human brain during exercise

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

History of the Pasteur effect and its pathobiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

The NADH oxidase system (external) of muscle mitochondria and its role in the oxidation of cytoplasmic NADH.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

The effect of high-intensity exhaustive exercise studied in isolated mitochondria from human skeletal muscle.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Lactate dehydrogenase is not a mitochondrial enzyme in human and mouse vastus lateralis muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Human skeletal muscle mitochondrial metabolism in youth and senescence: no signs of functional changes in ATP formation and mitochondrial oxidative capacity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Experimental evidence against the mitochondrial theory of aging. A study of isolated human skeletal muscle mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Myoglobin O2 desaturation during exercise. Evidence of limited O2 transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Lactate efflux from exercising human skeletal muscle: role of intracellular PO2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Cellular PO2 as a determinant of maximal mitochondrial O(2) consumption in trained human skeletal muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Skeletal muscle intracellular PO(2) assessed by myoglobin desaturation: response to graded exercise

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Effect of mild carboxy-hemoglobin on exercising skeletal muscle: intravascular and intracellular evidence

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Human skeletal muscle intracellular oxygenation: the impact of ambient oxygen availability

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Skeletal muscle glucose uptake during dynamic exercise in humans: role of muscle mass

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Early goal-directed therapy in the treatment of severe sepsis and septic shock

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Science vs. personal bias in acid-base physiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Biochemistry of exercise-induced metabolic acidosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Gluconeogenesis in humans with induced hyperlactatemia during low-intensity exercise

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Lactate is always the end product of glycolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Intracellular pH and distribution of weak acids across cell membranes. A study of D- and L-lactate and of DMO in rat diaphragm

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Lactate and pyruvate transport is dominated by a pH gradient-sensitive carrier in rat skeletal muscle sarcolemmal vesicles

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Lactate transport is mediated by a membrane-bound carrier in rat skeletal muscle sarcolemmal vesicles

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Lactate content and pH in muscle samples obtained after dynamic exercise

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

No evidence of an intracellular lactate shuttle in rat skeletal muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Loss of HIF-1α impairs GLUT4 translocation and glucose uptake by the skeletal muscle cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Reexamining cancer metabolism: Lactate production for carcinogenesis could be the purpose and explanation of the Warburg effect

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Cell respiration under hypoxia: facts and artefacts in mitochondrial oxygen kinetics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Lactate: the ultimate cerebral oxidative energy substrate?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Cerebral glycolysis: a century of persistent misunderstanding and misconception

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Lactate, not pyruvate, is neuronal aerobic glycolysis end product: an in vitro electrophysiological study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Glia are the main source of lactate utilized by neurons for recovery of function posthypoxia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

HIF-1, O(2), and the 3 PHDs: how animal cells signal hypoxia to the nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Hydroxylation of HIF-1: oxygen sensing at the molecular level

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Eight sages over five centuries share oxygen's discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Knockdown of lactate dehydrogenase A suppresses tumor growth and metastasis of human hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

A novel KLF4/LDHA signaling pathway regulates aerobic glycolysis in and progression of pancreatic cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Mechanistic Insights into the Efficacy of Sodium Bicarbonate Supplementation to Improve Athletic Performance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Lactate: a preferred fuel for human brain metabolism in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

A controlled clinical trial of dichloroacetate for treatment of lactic acidosis in adults. The Dichloroacetate-Lactic Acidosis Study Group

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Lactate kinetics and individual anaerobic threshold.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Pulmonary gas exchange and acid-base balance during exercise.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Oxidation of NADH via an "external" pathway in skeletal-muscle mitochondria and its possible role in the repayment of lactacid oxygen debt.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Lactate-mediated glia-neuronal signalling in the mammalian brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Functional Properties of the Mitochondrial Carrier System.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Gut luminal lactate release during gradual intestinal ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Effects of acute and chronic exercise on sarcolemmal MCT1 and MCT4 contents in human skeletal muscles: current status

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Targeting aspartate aminotransferase in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Muscle contraction increases lactate transport while reducing sarcolemmal MCT4, but not MCT1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Early increases in microcirculatory perfusion during protocol-directed resuscitation are associated with reduced multi-organ failure at 24 h in patients with sepsis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Metabolic signaling between neurons and glial cells: a short review

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Exercise Counteracts Aging-Related Memory Impairment: A Potential Role for the Astrocytic Metabolic Shuttle

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Effect of beta-adrenergic blockade on respiratory and metabolic responses to exercise

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Non-dopaminergic neurons partly expressing dopaminergic phenotype: distribution in the brain, development and functional significance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

The plasma membrane lactate transporter MCT4, but not MCT1, is up-regulated by hypoxia through a HIF-1alpha-dependent mechanism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Lactate as a fuel for mitochondrial respiration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Leg and arm lactate and substrate kinetics during exercise.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Targeting cancer metabolism: a therapeutic window opens

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Understanding the Warburg effect: the metabolic requirements of cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

A comparison of voluntary and electrically induced contractions by interleaved 1H- and 31P-NMRS in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Serum lactate as a marker of mortality in patients with hip fracture: A prospective study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Lactate dehydrogenase A negatively regulated by miRNAs promotes aerobic glycolysis and is increased in colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

THE METABOLISM OF TUMORS IN THE BODY

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Interaction of physiological mechanisms during exercise.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Oxygen debt in contracting dog skeletal muscle in situ

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Changes of intracellular pH due to repetitive stimulation of single fibres from mouse skeletal muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Evidence for a stromal-epithelial "lactate shuttle" in human tumors: MCT4 is a marker of oxidative stress in cancer-associated fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

The redox state of free nicotinamide-adenine dinucleotide in the cytoplasm and mitochondria of rat liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Quantitative dependence of mitochondrial oxidative phosphorylation on oxygen concentration: A mathematical model

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Using the "reverse Warburg effect" to identify high-risk breast cancer patients: stromal MCT4 predicts poor clinical outcome in triple-negative breast cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Selection and analysis of a mutant cell line defective in the hypoxia-inducible factor-1 alpha-subunit (HIF-1alpha). Characterization of hif-1alpha-dependent and -independent hypoxia-inducible gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Effects of prior dynamic leg exercise on static effort of the elbow flexors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

NAD+/NADH and NADP+/NADPH in cellular functions and cell death: regulation and biological consequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Negligible direct lactate oxidation in subsarcolemmal and intermyofibrillar mitochondria obtained from red and white rat skeletal muscle.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Cotransport of H+, lactate and H2O by membrane proteins in retinal pigment epithelium of bullfrog.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Wiring and volume transmission in the central nervous system: the concept of closed and open synapses

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Cellular and subcellular expression of monocarboxylate transporters in the pigment epithelium and retina of the rat

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Arterial catecholamine responses during exercise with acute and chronic high-altitude exposure

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Mitochondrial reticulum for cellular energy distribution in muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00421-017-3795-6

Measurement of aspartate aminotransferase activity: effects of oxamate

21 January 2018

1 reference

12 December 2020

The role of stress hormones in the catabolic metabolism of shock

1 reference

12 December 2020

Effect of acute and established anemia on O2 transport at rest, submaximal and maximal work

1 reference

12 December 2020

Efficiency of anaerobic work

1 reference

12 December 2020

Plasma noradrenaline and adrenaline concentrations and dopamine-beta-hydroxylase activity in patients with shock due to septicaemia, trauma and haemorrhage

1 reference

12 December 2020

The anatomic and metabolic source of lactate in shock

1 reference

12 December 2020

Contrasting influences of alterations in ventricular preload and afterload upon systemic hemodynamics, function, and metabolism of ischemic myocardium

1 reference

12 December 2020

Oxygen cost of running in trained and untrained men and women

1 reference

12 December 2020

Lactate metabolism in the dog during shock from hemorrhage, cardiac tamponade or endotoxin

1 reference

12 December 2020

Endogenous fuels in experimental shock

1 reference

12 December 2020

A new approach for the determination of ventilatory and lactate thresholds

1 reference

12 December 2020

Is the anaerobic threshold truly anaerobic?

1 reference

12 December 2020

Muscle lactate transport studied in sarcolemmal giant vesicles: dependence on fibre type and age

1 reference

12 December 2020

Net lactate uptake during progressive steady-level contractions in canine skeletal muscle

1 reference

12 December 2020

Myocardial lactate metabolism during exercise

1 reference

12 December 2020

Control of lactic acid metabolism in contracting muscles and during exercise

1 reference

12 December 2020

Lactate uptake by skeletal muscle

1 reference

12 December 2020

Coronary hemodynamics and myocardial metabolism during and after pacing stress in normal humans

1 reference

12 December 2020

Relationship of contraction capacity to metabolic changes during recovery from a fatiguing contraction

1 reference

12 December 2020

The oxygen dependence of mitochondrial oxidative phosphorylation measured by a new optical method for measuring oxygen concentration.

1 reference

12 December 2020

Effects of adrenergic agonists and antagonists on muscle O2 uptake and lactate metabolism

1 reference

12 December 2020

Disposal of blood [1-13C]lactate in humans during rest and exercise

1 reference

12 December 2020

Lactate extraction during net lactate release in legs of humans during exercise

1 reference

12 December 2020

Mechanisms and patterns of blood lactate increase during exercise in man.

1 reference

12 December 2020

Lactate-Supported Synaptic Function in the Rat Hippocampal Slice Preparation

1 reference

12 December 2020

Exercise intensity, training, diet, and lactate concentration in muscle and blood

1 reference

12 December 2020

Demonstration of the existence of an organo-specific NADH dehydrogenase in heart mitochondria

1 reference

12 December 2020

Lactate efflux is unrelated to intracellular PO2 in a working red muscle in situ

1 reference

12 December 2020

Rate-limiting steps for hepatic gluconeogenesis. Mechanism of oxamate inhibition of mitochondrial pyruvate metabolism

1 reference

12 December 2020

Anaerobic threshold: review of the concept and directions for future research

1 reference

12 December 2020

Historical remarks on the development of the aerobic-anaerobic threshold up to 1966

1 reference

12 December 2020

Regulation of lactate production and utilization in rat tumors in vivo

1 reference

12 December 2020

A cytoplasmic component of pyridine nucleotide fluorescence in rat diaphragm: evidence from comparisons with flavoprotein fluorescence

1 reference

12 December 2020

Lactate dehydrogenases: structure and function

1 reference

12 December 2020

The Pasteur effect and the relations between respiration and fermentation

1 reference

12 December 2020

Oxidation of NADH during contractions of circulated mammalian skeletal muscle

1 reference

12 December 2020

Bioenergetics and the problem of tumor growth

1 reference

12 December 2020

Effect of carbon monoxide on oxygen transport during exercise

1 reference

12 December 2020

Effect of pre-existing high blood lactate concentration on maximal exercise performance

1 reference

12 December 2020

Anaerobic threshold and respiratory gas exchange during exercise

1 reference

12 December 2020

Biochemical adaptations to exercise: anaerobic metabolism

1 reference

12 December 2020

1 reference

12 December 2020

The sympatho-adrenal factor in haemorrhagic shock

1 reference

12 December 2020

Effect of exercise and lactic acid infusion on individual free fatty acids of plasma.

1 reference

12 December 2020

Lactate metabolism of contracting dog skeletal muscle in situ

1 reference

12 December 2020

Breakdown and Resynthesis of Phosphorylcreatine and Adenosine Triphosphate in Connection with Muscular Work in Man

1 reference

12 December 2020

Cytochrome c as an electron shuttle between the outer and inner mitochondrial membranes.

1 reference

12 December 2020

In Vivo Determination of the Pyridine Nucleotide Reduction Charge by Carbon-13 Nuclear Magnetic Resonance Spectroscopy

1 reference

12 December 2020

The anaerobic threshold measurement to evaluate exercise performance

1 reference

12 December 2020

"Anaerobic threshold": problems of determination and validation

1 reference

12 December 2020

Lactate production in a pure red muscle in absence of anoxia: mechanisms and significance

1 reference

12 December 2020

Lactate accumulation in fully aerobic, working, dog gracilis muscle

1 reference

12 December 2020

Lactate accumulation relative to the anaerobic and respiratory compensation thresholds

1 reference

12 December 2020

Anaerobic threshold, blood lactate, and muscle metabolites in progressive exercise

1 reference

12 December 2020

Lactic acid infusion in dogs: effects of varying infusate pH

1 reference

12 December 2020

Does the gas exchange anaerobic threshold occur at a fixed blood lactate concentration of 2 or 4 mM?

1 reference

12 December 2020

Quantitative aspects of L(+)-lactate metabolism in human beings

1 reference

12 December 2020

A comparison of gas exchange indices used to detect the anaerobic threshold

1 reference

12 December 2020

Acute substantial benefit of inotropic therapy with amrinone on exercise hemodynamics and metabolism in severe congestive heart failure

1 reference

12 December 2020

Muscle respiratory capacity and fiber type as determinants of the lactate threshold

1 reference

12 December 2020

Determination of myoglobin saturation of frozen specimens using a reflecting cryospectrophotometer

1 reference

12 December 2020

Metabolic end products inhibit sarcoplasmic reticulum Ca2+ release and [3H]ryanodine binding

1 reference

12 December 2020

Increased [lactate] in working dog muscle reduces tension development independent of pH.

1 reference

12 December 2020

Lactate influx into red blood cells of athletic and nonathletic species

1 reference

12 December 2020

Plasma volume and ion regulation during exercise after low- and high-carbohydrate diets

1 reference

12 December 2020

Factors affecting the rate and energetics of mitochondrial oxidative phosphorylation

1 reference

12 December 2020

L-(+)-lactate infusion into working dog gastrocnemius: no evidence lactate per se mediates VO2 slow component

1 reference

12 December 2020

Striatal L-dopa decarboxylase activity in Parkinson's disease in vivo: implications for the regulation of dopamine synthesis

1 reference

12 December 2020

Dissociation of [H+] from fatigue in human muscle detected by high time resolution 31P-NMR

1 reference

12 December 2020

The slow component of oxygen uptake kinetics in humans.

1 reference

12 December 2020

Influence of physiological L(+)-lactate concentrations on contractility of skinned striated muscle fibers of rabbit

1 reference

12 December 2020

Hypoxia Response Elements in the Aldolase A, Enolase 1, and Lactate Dehydrogenase A Gene Promoters Contain Essential Binding Sites for Hypoxia-inducible Factor 1

1 reference

12 December 2020

Brain lactate, not glucose, fuels the recovery of synaptic function from hypoxia upon reoxygenation: an in vitro study

1 reference

12 December 2020

Systemic and regional effects of experimental gradual splanchnic ischemia

1 reference

12 December 2020

Brain lactate is an obligatory aerobic energy substrate for functional recovery after hypoxia: further in vitro validation.

1 reference

12 December 2020

Lactate influx into red blood cells from trained and untrained human subjects

1 reference

12 December 2020

Effects of CO2-induced acidification on the fatigue resistance of single mouse muscle fibers at 28 degrees C

1 reference

12 December 2020

The relationship between plasma lactate parameters, Wpeak and 1-h cycling performance in women

1 reference

12 December 2020

The validity of the lactate minimum test for determination of the maximal lactate steady state

1 reference

12 December 2020

The V(O2) slow component for severe exercise depends on type of exercise and is not correlated with time to fatigue

1 reference

12 December 2020

Differential depression of myocardial function and metabolism by lactate and H+

1 reference

12 December 2020

Effects of lactate on force production by mouse EDL muscle: implications for the development of fatigue

1 reference

12 December 2020

Stimulation of both aerobic glycolysis and Na(+)-K(+)-ATPase activity in skeletal muscle by epinephrine or amylin.

1 reference

12 December 2020

Myoglobin desaturation with exercise intensity in human gastrocnemius muscle

1 reference

12 December 2020

Regulation of skeletal muscle glycogen phosphorylase and PDH during maximal intermittent exercise

1 reference

12 December 2020

Brain uptake of glutamate: food for thought

1 reference

12 December 2020

Lactate improves cardiac efficiency after hemorrhagic shock

1 reference

12 December 2020

Cardiac energy metabolism in patients with chest pain and normal coronary angiograms

1 reference

12 December 2020

The oxidation of added NADH by intact heart mitochondria

1 reference

12 December 2020

L-Lactate transport into rat heart mitochondria and reconstruction of the L-lactate/pyruvate shuttle.

1 reference

12 December 2020

Mitochondrial respiration at low levels of oxygen and cytochrome c.

1 reference

12 December 2020

Lactate shuttles in nature

1 reference

12 December 2020

Aerobic fitness reduces brain tissue loss in aging humans.

1 reference

12 December 2020

The respiratory chain and oxidative phosphorylation

1 reference

12 December 2020

The biochemical approach to the cancer problem

1 reference

12 December 2020

DETECTING THE THRESHOLD OF ANAEROBIC METABOLISM IN CARDIAC PATIENTS DURING EXERCISE

1 reference

12 December 2020

Phosphorylation coupled to oxidation of dihydrodiphosphopyridine nucleotide

1 reference

12 December 2020

The development of muscle-chemistry, a lesson in neurophysiology

1 reference

12 December 2020

Hypoxia inducible factor-1 and facilitative glucose transporters GLUT1 and GLUT3: putative molecular components of the oxygen and glucose sensing apparatus in articular chondrocytes

1 reference

12 December 2020

Point: lactic acid accumulation is an advantage during muscle activity

1 reference

12 December 2020

Counterpoint: lactic acid accumulation is a disadvantage during muscle activity

1 reference

12 December 2020

Low cell pH depresses peak power in rat skeletal muscle fibres at both 30 degrees C and 15 degrees C: implications for muscle fatigue

1 reference

12 December 2020

Lactic acid in amphibian muscle

1 reference

12 December 2020

Alterations in the lactic acid content of the blood as a result of light exercise, and associated changes in the co(2)-combining power of the blood and in the alveolar co(2) pressure

1 reference

12 December 2020

Additive protective effects of the addition of lactic acid and adrenaline on excitability and force in isolated rat skeletal muscle depressed by elevated extracellular K+

1 reference

12 December 2020

Counterpoint: Lactic acid is not the only physicochemical contributor to the acidosis of exercise

1 reference

12 December 2020

1 reference

12 December 2020

Tumor metabolism: cancer cells give and take lactate

1 reference

12 December 2020

Targeting lactate-fueled respiration selectively kills hypoxic tumor cells in mice

1 reference

12 December 2020

Monocarboxylate transporters: past, present, and future

1 reference

12 December 2020

The concentration of blood lactic acid in man during muscular work in relation to the partial pressure of oxygen of the inspired air

1 reference

12 December 2020

L-lactate metabolism can occur in normal and cancer prostate cells via the novel mitochondrial L-lactate dehydrogenase.

1 reference

12 December 2020

Volume regulation in mammalian skeletal muscle: the role of sodium-potassium-chloride cotransporters during exposure to hypertonic solutions

1 reference

12 December 2020

Fuel for cancer cells?

1 reference

12 December 2020

Lactate and the GPR81 receptor in metabolic regulation: implications for adipose tissue function and fatty acid utilisation by muscle during exercise

1 reference

12 December 2020

Malate-aspartate shuttle and exogenous NADH/cytochrome c electron transport pathway as two independent cytosolic reducing equivalent transfer systems

1 reference

12 December 2020

l-Lactate metabolism in HEP G2 cell mitochondria due to the l-lactate dehydrogenase determines the occurrence of the lactate/pyruvate shuttle and the appearance of oxaloacetate, malate and citrate outside mitochondria

1 reference

12 December 2020

Lactate clearance as a predictor of mortality in trauma patients

1 reference

12 December 2020

Regulation of cellular gas exchange, oxygen sensing, and metabolic control

1 reference

12 December 2020

A randomized trial of protocol-based care for early septic shock

1 reference

12 December 2020

A patient with acute liver failure and extreme hypoglycaemia with lactic acidosis who was not in a coma: causes and consequences of lactate-protected hypoglycaemia.

1 reference

12 December 2020

Lactate metabolism in trauma

1 reference

12 December 2020

Carl Wilhelm Scheele, the discoverer of oxygen, and a very productive chemist

1 reference

12 December 2020

Fluid transport by the cornea endothelium is dependent on buffering lactic acid efflux.

1 reference

12 December 2020

The Basic Science of Exercise Fatigue

1 reference

12 December 2020

The Role of Acidosis in Fatigue: Pro Perspective

1 reference

12 December 2020

Acidosis Is Not a Significant Cause of Skeletal Muscle Fatigue

1 reference

12 December 2020

Lactate Shuttles in Neuroenergetics-Homeostasis, Allostasis and Beyond.

1 reference

12 December 2020

10.1007/S00421-017-3795-6

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29322250%20AND%20SRC:MED&resulttype=core&format=json

9 April 2020

1 reference