β-Secretase BACE1 regulates hippocampal and reconstituted M-currents in a β-subunit-like fashion. (Q48221664)

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1 March 2020

title

β-Secretase BACE1 regulates hippocampal and reconstituted M-currents in a β-subunit-like fashion (English)

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10

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Sandra Lehnert

5

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Matthias Nissen

7

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Elke Edelmann

8

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Tobias Huth

11

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12

Christian Alzheimer

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author name string

Sabine Hessler

1

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Fang Zheng

2

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Stephanie Hartmann

3

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Andrea Rittger

4

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Meike Völkel

6

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Paul Saftig

9

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language of work or name

English

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publication date

1 February 2015

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published in

Journal of Neuroscience

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volume

35

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issue

8

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page(s)

3298-3311

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describes a project that uses

1 March 2020

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6605557/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Molecular cloning and functional expression of KCNQ5, a potassium channel subunit that may contribute to neuronal M-current diversity

1 reference

12 December 2020

KCNQ5, a novel potassium channel broadly expressed in brain, mediates M-type currents

1 reference

12 December 2020

Modulation of KCNQ2/3 potassium channels by the novel anticonvulsant retigabine

1 reference

12 December 2020

Neuronal KCNQ potassium channels: physiology and role in disease.

1 reference

12 December 2020

Properties of single M-type KCNQ2/KCNQ3 potassium channels expressed in mammalian cells

1 reference

12 December 2020

Molecular correlates of the M-current in cultured rat hippocampal neurons

1 reference

12 December 2020

Two forms of electrical resonance at theta frequencies, generated by M-current, h-current and persistent Na+ current in rat hippocampal pyramidal cells

1 reference

12 December 2020

M channels containing KCNQ2 subunits modulate norepinephrine, aspartate, and GABA release from hippocampal nerve terminals.

1 reference

12 December 2020

Single-channel analysis of KCNQ K+ channels reveals the mechanism of augmentation by a cysteine-modifying reagent.

1 reference

12 December 2020

Three mechanisms underlie KCNQ2/3 heteromeric potassium M-channel potentiation.

1 reference

12 December 2020

Conditional transgenic suppression of M channels in mouse brain reveals functions in neuronal excitability, resonance and behavior.

1 reference

12 December 2020

The new anticonvulsant retigabine favors voltage-dependent opening of the Kv7.2 (KCNQ2) channel by binding to its activation gate

1 reference

12 December 2020

beta Subunits of voltage-gated sodium channels are novel substrates of beta-site amyloid precursor protein-cleaving enzyme (BACE1) and gamma-secretase

1 reference

12 December 2020

Kv7/KCNQ/M and HCN/h, but not KCa2/SK channels, contribute to the somatic medium after-hyperpolarization and excitability control in CA1 hippocampal pyramidal cells.

1 reference

12 December 2020

Molecular determinants of KCNQ (Kv7) K+ channel sensitivity to the anticonvulsant retigabine.

1 reference

12 December 2020

Phenotypic and biochemical analyses of BACE1- and BACE2-deficient mice

1 reference

12 December 2020

Regulation of Kv7 (KCNQ) K+ channel open probability by phosphatidylinositol 4,5-bisphosphate.

1 reference

12 December 2020

A spontaneous mutation involving Kcnq2 (Kv7.2) reduces M-current density and spike frequency adaptation in mouse CA1 neurons.

1 reference

12 December 2020

Axo-somatic and apical dendritic Kv7/M channels differentially regulate the intrinsic excitability of adult rat CA1 pyramidal cells

1 reference

12 December 2020

Structural determinants of M-type KCNQ (Kv7) K+ channel assembly.

1 reference

12 December 2020

Kv7/KCNQ/M-channels in rat glutamatergic hippocampal axons and their role in regulation of excitability and transmitter release.

1 reference

12 December 2020

Rapid chemically induced changes of PtdIns(4,5)P2 gate KCNQ ion channels

1 reference

12 December 2020

Direct observation of individual endogenous protein complexes in situ by proximity ligation

1 reference

12 December 2020

CellProfiler: image analysis software for identifying and quantifying cell phenotypes

1 reference

12 December 2020

M-channels (Kv7/KCNQ channels) that regulate synaptic integration, excitability, and spike pattern of CA1 pyramidal cells are located in the perisomatic region.

1 reference

12 December 2020

Enzyme domain affects the movement of the voltage sensor in ascidian and zebrafish voltage-sensing phosphatases

1 reference

12 December 2020

A carboxy-terminal inter-helix linker as the site of phosphatidylinositol 4,5-bisphosphate action on Kv7 (M-type) K+ channels.

1 reference

12 December 2020

Homomeric and heteromeric assembly of KCNQ (Kv7) K+ channels assayed by total internal reflection fluorescence/fluorescence resonance energy transfer and patch clamp analysis

1 reference

12 December 2020

Determinants within the turret and pore-loop domains of KCNQ3 K+ channels governing functional activity.

1 reference

12 December 2020

Non-proteolytic effect of beta-site APP-cleaving enzyme 1 (BACE1) on sodium channel function

1 reference

12 December 2020

Contribution of KCNQ2 and KCNQ3 to the medium and slow afterhyperpolarization currents

1 reference

12 December 2020

Neural KCNQ (Kv7) channels

1 reference

12 December 2020

Voltage-gated potassium channels as therapeutic targets

1 reference

12 December 2020

Evidence for dimeric BACE-mediated APP processing.

1 reference

12 December 2020

1 reference

12 December 2020

BACE1 deficiency causes altered neuronal activity and neurodegeneration

1 reference

12 December 2020

BACE1-/- mice exhibit seizure activity that does not correlate with sodium channel level or axonal localization

1 reference

12 December 2020

The Voltage-Sensing Domain of K(v)7.2 Channels as a Molecular Target for Epilepsy-Causing Mutations and Anticonvulsants.

1 reference

12 December 2020

Contributions of Kv7-mediated potassium current to sub- and suprathreshold responses of rat layer II/III neocortical pyramidal neurons.

1 reference

12 December 2020

Neuronal basis of age-related working memory decline

1 reference

12 December 2020

Restoration of ion channel function in deafness-causing KCNQ4 mutants by synthetic channel openers

1 reference

12 December 2020

Differential effects of Kv7 (M-) channels on synaptic integration in distinct subcellular compartments of rat hippocampal pyramidal neurons

1 reference

12 December 2020

M channel enhancers and physiological M channel block

1 reference

12 December 2020

Structural requirements of membrane phospholipids for M-type potassium channel activation and binding

1 reference

12 December 2020

Alzheimer mechanisms and therapeutic strategies

1 reference

12 December 2020

Voltage-dependent Na+ channels as targets of BACE1 - implications for neuronal firing and beyond

1 reference

12 December 2020

Functional significance of M-type potassium channels in nociceptive cutaneous sensory endings

1 reference

12 December 2020

M-type potassium channels modulate Schaffer collateral-CA1 glutamatergic synaptic transmission

1 reference

12 December 2020

Secretome protein enrichment identifies physiological BACE1 protease substrates in neurons

1 reference

12 December 2020

Regulation of voltage-gated potassium channels by PI(4,5)P2

1 reference

12 December 2020

Levetiracetam suppresses neuronal network dysfunction and reverses synaptic and cognitive deficits in an Alzheimer's disease model

1 reference

12 December 2020

Phosphatidylinositol 4,5-bisphosphate alters pharmacological selectivity for epilepsy-causing KCNQ potassium channels

1 reference

12 December 2020

Seizures and epileptiform activity in the early stages of Alzheimer disease

1 reference

12 December 2020

High activities of BACE1 in brains with mild cognitive impairment

1 reference

12 December 2020

Targeting the β secretase BACE1 for Alzheimer's disease therapy

1 reference

12 December 2020

Heteromeric Kv7.2/7.3 channels differentially regulate action potential initiation and conduction in neocortical myelinated axons.

1 reference

12 December 2020

Function, therapeutic potential and cell biology of BACE proteases: current status and future prospects

1 reference

12 December 2020

Muscarinic suppression of a novel voltage-sensitive K+ current in a vertebrate neurone

1 reference

12 December 2020

Coassembly of K(V)LQT1 and minK (IsK) proteins to form cardiac I(Ks) potassium channel

1 reference

12 December 2020

KCNQ2 and KCNQ3 potassium channel subunits: molecular correlates of the M-channel

1 reference

12 December 2020

10.1523/JNEUROSCI.3127-14.2015

Identifiers

DOI

1 reference

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1 March 2020

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1 March 2020

PubMed publication ID

25716831

1 reference