BACE1 deficiency causes altered neuronal activity and neurodegeneration (Q30495458)

13 October 2017

BACE1 deficiency causes altered neuronal activity and neurodegeneration (English)

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13 October 2017

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Xiangyou Hu

1

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13 October 2017

Xiangdong Zhou

2

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13 October 2017

Wanxia He

3

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13 October 2017

Jun Yang

4

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13 October 2017

Wencheng Xiong

5

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13 October 2017

Philip Wong

6

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13 October 2017

Christopher G Wilson

7

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13 October 2017

Riqiang Yan

8

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13 October 2017

language of work or name

English

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publication date

1 June 2010

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13 October 2017

Journal of Neuroscience

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13 October 2017

30

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13 October 2017

26

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13 October 2017

8819-8829

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describes a project that uses

13 October 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2902368/fullTextXML

inferred from PubMed Central ID database lookup

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20 June 2018

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Sodium-channel defects in benign familial neonatal-infantile seizures

20 June 2018

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20 June 2018

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20 June 2018

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BACE knockout mice are healthy despite lacking the primary beta-secretase activity in brain: implications for Alzheimer's disease therapeutics

20 June 2018

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20 June 2018

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BACE1 is the major beta-secretase for generation of Abeta peptides by neurons

20 June 2018

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Mice deficient in BACE1, the Alzheimer's beta-secretase, have normal phenotype and abolished beta-amyloid generation

20 June 2018

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20 June 2018

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20 June 2018

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Identification of a Novel Aspartic Protease (Asp 2) as β-Secretase

20 June 2018

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Purification and cloning of amyloid precursor protein beta-secretase from human brain

20 June 2018

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Membrane-anchored aspartyl protease with Alzheimer's disease beta-secretase activity

20 June 2018

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20 June 2018

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Modification of seizure activity by electrical stimulation. II. Motor seizure

20 June 2018

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Sodium channel density in hypomyelinated brain increased by myelin basic protein gene deletion

20 June 2018

1 reference

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Elevated expression of type II Na+ channels in hypomyelinated axons of shiverer mouse brain

20 June 2018

1 reference

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BACE1 gene deletion: impact on behavioral function in a model of Alzheimer's disease.

20 June 2018

1 reference

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Bace1 modulates myelination in the central and peripheral nervous system.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2902368

Effects in neocortical neurons of mutations of the Na(v)1.2 Na+ channel causing benign familial neonatal-infantile seizures.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2902368

Enhanced susceptibility to kainate-induced seizures, neuronal apoptosis, and death in mice lacking gangliotetraose gangliosides: protection with LIGA 20, a membrane-permeant analog of GM1.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2902368

Phenotypic and biochemical analyses of BACE1- and BACE2-deficient mice

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2902368

Differential control of clustering of the sodium channels Na(v)1.2 and Na(v)1.6 at developing CNS nodes of Ranvier

26 November 2018

1 reference

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A gain-of-function mutation in the sodium channel gene Scn2a results in seizures and behavioral abnormalities.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2902368

Generation and propagation of 4-AP-induced epileptiform activity in neonatal intact limbic structures in vitro

26 November 2018

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12 December 2020

Reduced sodium channel density, altered voltage dependence of inactivation, and increased susceptibility to seizures in mice lacking sodium channel beta 2-subunits

1 reference

12 December 2020

Identification of a mutant amyloid peptide that predominantly forms neurotoxic protofibrillar aggregates

1 reference

12 December 2020

Activity-evoked capacitative Ca2+ entry: implications in synaptic plasticity.

1 reference

12 December 2020

A novel SCN2A mutation in family with benign familial infantile seizures

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12 December 2020

10.1523/JNEUROSCI.1334-10.2010

Identifiers

DOI

1 reference

13 October 2017

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13 October 2017

1 reference