Synthetic transcription elongation factors license transcription across repressive chromatin. (Q48206894)

http://europepmc.org/abstract/MED/29192133

9 February 2018

title

Synthetic transcription elongation factors license transcription across repressive chromatin. (English)

1 reference

http://europepmc.org/abstract/MED/29192133

9 February 2018

author

Kathleen A Worringer

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29192133%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Graham S Erwin

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29192133%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Matthew P Grieshop

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29192133%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Jun Qi

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29192133%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Matthew Lawlor

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29192133%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Istaq Ahmad

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29192133%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Anna McNally

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29192133%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Deeba Nadeem Syed

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29192133%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Asuka Eguchi

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29192133%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Jay Bradner

21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29192133%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Aseem Z Ansari

22

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29192133%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

author name string

Asfa Ali

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29192133%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Deepak Kumar

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29192133%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Natalia Teider

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29192133%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Rajeev Sivasankaran

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29192133%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Md Ashraf

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29192133%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Justin Jeffery

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29192133%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Mousheng Xu

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29192133%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Paul M C Park

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29192133%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Hasan Mukhtar

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29192133%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Achal K Srivastava

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29192133%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Mohammed Faruq

20

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29192133%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

language of work or name

English

0 references

publication date

30 November 2017

1 reference

http://europepmc.org/abstract/MED/29192133

9 February 2018

published in

Science

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29192133%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

volume

358

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29192133%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

issue

6370

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29192133%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

page(s)

1617-1622

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29192133%20AND%20SRC:MED&resulttype=core&format=json

Pause & go: from the discovery of RNA polymerase pausing to its functional implications.

11 June 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6037176

Genomic targeting of epigenetic probes using a chemically tailored Cas9 system

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6037176

Reprogramming cell fate with a genome-scale library of artificial transcription factors.

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6037176

Synthetic genome readers target clustered binding sites across diverse chromatin states

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6037176

Abundant contribution of short tandem repeats to gene expression variation in humans

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6037176

A Bead-Based Proximity Assay for BRD4 Ligand Discovery

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6037176

Expanded GAA repeats impede transcription elongation through the FXN gene and induce transcriptional silencing that is restricted to the FXN locus

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6037176

A cost-effective RNA sequencing protocol for large-scale gene expression studies

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6037176

Quantitative ChIP-Seq normalization reveals global modulation of the epigenome.

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6037176

Selective conversion of fibroblasts into peripheral sensory neurons

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6037176

Epigenetic therapy for Friedreich ataxia

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6037176

Controlling gene networks and cell fate with precision-targeted DNA-binding proteins and small-molecule-based genome readers

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6037176

Mapping polyamide-DNA interactions in human cells reveals a new design strategy for effective targeting of genomic sites

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6037176

deepTools: a flexible platform for exploring deep-sequencing data.

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6037176

R-loops associated with triplet repeat expansions promote gene silencing in Friedreich ataxia and fragile X syndrome.

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6037176

A Potential New Therapeutic Approach for Friedreich Ataxia: Induction of Frataxin Expression With TALE Proteins

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6037176

A GAA repeat expansion reporter model of Friedreich's ataxia recapitulates the genomic context and allows rapid screening of therapeutic compounds.

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6037176

Animal and cellular models of Friedreich ataxia.

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6037176

Gene regulation and epigenetics in Friedreich's ataxia

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6037176

Enrichr: interactive and collaborative HTML5 gene list enrichment analysis tool

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6037176

Transcriptional regulation and its misregulation in disease.

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6037176

EBSeq: an empirical Bayes hierarchical model for inference in RNA-seq experiments

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6037176

Friedreich ataxia: neuropathology revised

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6037176

Promoter-proximal pausing of RNA polymerase II: emerging roles in metazoans

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6037176

The super elongation complex (SEC) family in transcriptional control

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6037176

Robust cardiomyocyte differentiation from human pluripotent stem cells via temporal modulation of canonical Wnt signaling.

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6037176

RNA polymerase II elongation control

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6037176

A gene expression phenotype in lymphocytes from Friedreich ataxia patients

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6037176

RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6037176

Selective inhibition of BET bromodomains

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6037176

Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6037176

Long intronic GAA repeats causing Friedreich ataxia impede transcription elongation

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6037176

Specificity landscapes of DNA binding molecules elucidate biological function

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6037176

Diagnosis and treatment of Friedreich ataxia: a European perspective

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6037176

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6037176

Repeat-induced epigenetic changes in intron 1 of the frataxin gene and its consequences in Friedreich ataxia

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6037176

Exploring the limits of benzimidazole DNA-binding oligomers for the hypoxia inducible factor (HIF) site.

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6037176

DNA sequence-specific polyamides alleviate transcription inhibition associated with long GAA.TTC repeats in Friedreich's ataxia

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6037176

Recruitment of P-TEFb for stimulation of transcriptional elongation by the bromodomain protein Brd4

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6037176

Crystal structures of nucleosome core particles in complex with minor groove DNA-binding ligands

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6037176

Molecular recognition of DNA by small molecules

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6037176

The relationship between trinucleotide (GAA) repeat length and clinical features in Friedreich ataxia

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6037176

26 August 2018

Identifiers

DOI

10.1126/SCIENCE.AAN6414

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29192133%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

0 references

release_vikktajdwvhyji46u2nwbntyky

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29192133%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

1 reference