Muscle atrophy is associated with cervical spinal motoneuron loss in BACHD mouse model for Huntington's disease. (Q48140308)

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30 March 2020

title

Muscle atrophy is associated with cervical spinal motoneuron loss in BACHD mouse model for Huntington's disease (English)

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Cristina Guatimosim

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author name string

Priscila Aparecida Costa Valadão

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Bárbara Campos de Aragão

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Jéssica Neves Andrade

3

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Matheus Proença S Magalhães-Gomes

4

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Giselle Foureaux

5

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Julliane Vasconcelos Joviano-Santos

6

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José Carlos Nogueira

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Juan Carlos Tapia

9

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language of work or name

English

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publication date

30 January 2017

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European Journal of Neuroscience

30 March 2020

published in

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volume

45

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issue

6

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page(s)

785-796

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History of genetic disease: the molecular genetics of Huntington disease - a history

30 March 2020

cites work

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Lysosomal abnormalities in degenerating neurons link neuronal compromise to senile plaque development in Alzheimer disease

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Enhanced mitochondrial biogenesis ameliorates disease phenotype in a full-length mouse model of Huntington's disease

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Full-length human mutant huntingtin with a stable polyglutamine repeat can elicit progressive and selective neuropathogenesis in BACHD mice

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Evaluation of antidepressant-related behavioral responses in mice lacking the serotonin transporter

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Characterization and localization of the Huntington disease gene product

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A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.

21 January 2018

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Insoluble detergent-resistant aggregates form between pathological and nonpathological lengths of polyglutamine in mammalian cells

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Changes in sizes of cortical and lower motor neurons in amyotrophic lateral sclerosis

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Neck kinematics and sternocleidomastoid muscle activation during neck rotation in subjects with forward head posture

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Mitochondrial loss, dysfunction and altered dynamics in Huntington's disease

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Peripheral axotomy slows motoneuron degeneration in a transgenic mouse line expressing mutant SOD1 G93A.

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Huntington's disease gene (IT15) is widely expressed in human and rat tissues

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Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice

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Synaptic vesicle pools at diaphragm neuromuscular junctions vary with motoneuron soma, not axon terminal, inactivity.

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Motor deficits associated with Huntington's disease occur in the absence of striatal degeneration in BACHD transgenic mice

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Quantification of subcellular glycogen in resting human muscle: granule size, number, and location

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Systematic behavioral evaluation of Huntington's disease transgenic and knock-in mouse models

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Huntington's disease is a multi-system disorder.

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Formation of polyglutamine inclusions in a wide range of non-CNS tissues in the HdhQ150 knock-in mouse model of Huntington's disease

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Distinct effects of subcellular glycogen localization on tetanic relaxation time and endurance in mechanically skinned rat skeletal muscle fibres.

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Inhibition of caspase-1 slows disease progression in a mouse model of Huntington's disease

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Inclusion formation in Huntington's disease R6/2 mouse muscle cultures

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AN ELECTRON MICROSCOPE STUDY OF DENERVATION ATROPHY IN RED AND WHITE SKELETAL MUSCLE FIBERS

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Effects of in vivo injury on the neuromuscular junction in healthy and dystrophic muscles

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Mitochondrial structural and functional dynamics in Huntington's disease

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Progressive abnormalities in skeletal muscle and neuromuscular junctions of transgenic mice expressing the Huntington's disease mutation

21 January 2018

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Reduced expression of the vesicular acetylcholine transporter and neurotransmitter content affects synaptic vesicle distribution and shape in mouse neuromuscular junction

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THE FINE STRUCTURE OF LIPOFUSCIN AGE PIGMENT IN THE NERVOUS SYSTEM OF AGED MICE.

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Formation of polyglutamine inclusions in non-CNS tissue

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Synaptic dysfunction in Huntington's disease: a new perspective.

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Postural stability in patients with Huntington's disease

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Neuroprotective effects of M826, a reversible caspase-3 inhibitor, in the rat malonate model of Huntington's disease

21 January 2018

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Assessment of the nutrition status of patients with Huntington's disease.

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Polyglutamine expansion as a pathological epitope in Huntington's disease and four dominant cerebellar ataxias

21 January 2018

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Shared resistance to aging and ALS in neuromuscular junctions of specific muscles

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Beyond the brain: widespread pathology in Huntington's disease

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Atrophy and degeneration in sciatic nerve of presymptomatic mice carrying the Huntington's disease mutation

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Mechanisms for fiber-type specificity of skeletal muscle atrophy

21 January 2018

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Motor neuron apoptosis and neuromuscular junction perturbation are prominent features in a Drosophila model of Fus-mediated ALS

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Homologous recombination based modification in Escherichia coli and germline transmission in transgenic mice of a bacterial artificial chromosome.

21 January 2018

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Skeletal muscle pathology in Huntington's disease

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21 January 2018

Identifiers

DOI

10.1111/EJN.13510

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27992085%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

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