Determination of the methylation status of MGMT in different regions within glioblastoma multiforme (Q48116112)

8 February 2018

title

Determination of the methylation status of MGMT in different regions within glioblastoma multiforme (English)

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8 February 2018

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5

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author name string

Mark G Hamilton

1

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Gloria Roldán

2

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Anthony Magliocco

3

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John B McIntyre

4

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Jacob C Easaw

6

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8 February 2018

publication date

21 July 2010

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Journal of Neuro-Oncology

published in

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volume

102

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8 February 2018

issue

2

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page(s)

255-260

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8 February 2018

https://scigraph.springernature.com/pub.10.1007/s11060-010-0307-5

exact match

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Clinical trial substantiates the predictive value of O-6-methylguanine-DNA methyltransferase promoter methylation in glioblastoma patients treated with temozolomide

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Effect of fixatives and tissue processing on the content and integrity of nucleic acids

21 January 2018

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The correlation and prognostic significance of MGMT promoter methylation and MGMT protein in glioblastomas

21 January 2018

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Prognostic significance of the immunohistochemical expression of O6-methylguanine-DNA methyltransferase, P-glycoprotein, and multidrug resistance protein-1 in glioblastomas

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MGMT promoter methylation in malignant gliomas: ready for personalized medicine?

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Relevance of MSP assay for the detection of MGMT promoter hypermethylation in glioblastomas.

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12 December 2020

A comparative study of the quality of DNA obtained from fresh frozen and formalin-fixed decalcified paraffin-embedded bone marrow trephine biopsy specimens using two different methods

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Apoptosis induced by DNA damage O6-methylguanine is Bcl-2 and caspase-9/3 regulated and Fas/caspase-8 independent

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Prevention of irradiation-induced glioma cell invasion by temozolomide involves caspase 3 activity and cleavage of focal adhesion kinase.

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Reliability and reproducibility of PCR-based testing of O6-methylguanine-DNA methyltransferase gene (MGMT) promoter methylation status in formalin-fixed and paraffin-embedded neurosurgical biopsy specimens.

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In vitro evaluation of temozolomide combined with X-irradiation

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Intratumoral homogeneity of MGMT promoter hypermethylation as demonstrated in serial stereotactic specimens from anaplastic astrocytomas and glioblastomas

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Mismatch repair mutations override alkyltransferase in conferring resistance to temozolomide but not to 1,3-bis(2-chloroethyl)nitrosourea.

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10.1007/S11060-010-0307-5

Identifiers

DOI

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8 February 2018

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8 February 2018