Processing of mouse proglucagon by recombinant prohormone convertase 1 and immunopurified prohormone convertase 2 in vitro. (Q48074333)

8 February 2018

title

Processing of mouse proglucagon by recombinant prohormone convertase 1 and immunopurified prohormone convertase 2 in vitro. (English)

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8 February 2018

author name string

M E Rothenberg

1

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8 February 2018

C D Eilertson

2

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8 February 2018

K Klein

3

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Y Zhou

4

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I Lindberg

5

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8 February 2018

J K McDonald

6

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R B Mackin

7

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B D Noe

8

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8 February 2018

language of work or name

English

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publication date

1 April 1995

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8 February 2018

Journal of Biological Chemistry

published in

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8 February 2018

volume

270

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8 February 2018

issue

17

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8 February 2018

page(s)

10136-10146

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8 February 2018

Precursors to regulatory peptides: their proteolytic processing

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PC1 and PC2 are proprotein convertases capable of cleaving proopiomelanocortin at distinct pairs of basic residues

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Enzymes required for yeast prohormone processing

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Furin is a subtilisin-like proprotein processing enzyme in higher eukaryotes

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Isolation and functional expression of a mammalian prohormone processing enzyme, murine prohormone convertase 1.

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Cloning and Functional Expression of a Novel Endoprotease Involved in Prohormone Processing at Dibasic Sites1

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Isolation of the putative structural gene for the lysine-arginine-cleaving endopeptidase required for processing of yeast prepro-alpha-factor

21 January 2018

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Identification of a Second Human Subtilisin-Like Protease Gene in thefes/fpsRegion of Chromosome 15

21 January 2018

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Structural homology between the human fur gene product and the subtilisin-like protease encoded by yeast KEX2

21 January 2018

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Expression of a human proprotein processing enzyme: correct cleavage of the von Willebrand factor precursor at a paired basic amino acid site

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Isolation of two complementary deoxyribonucleic acid clones from a rat insulinoma cell line based on similarities to Kex2 and furin sequences and the specific localization of each transcript to endocrine and neuroendocrine tissues in rats

21 January 2018

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cDNA sequence of two distinct pituitary proteins homologous to Kex2 and furin gene products: tissue-specific mRNAs encoding candidates for pro-hormone processing proteinases

21 January 2018

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Identification of a cDNA encoding a second putative prohormone convertase related to PC2 in AtT20 cells and islets of Langerhans

21 January 2018

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Identification of novel cDNAs encoding human kexin-like protease, PACE4 isoforms

21 January 2018

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Testicular expression of PC4 in the rat: molecular diversity of a novel germ cell-specific Kex2/subtilisin-like proprotein convertase

21 January 2018

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cDNA structure of the mouse and rat subtilisin/kexin-like PC5: a candidate proprotein convertase expressed in endocrine and nonendocrine cells.

21 January 2018

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Identification and functional expression of a new member of the mammalian Kex2-like processing endoprotease family: its striking structural similarity to PACE4

21 January 2018

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A novel member, PC7, of the mammalian kexin-like protease family: homology to PACE4A, its brain-specific expression and identification of isoforms

21 January 2018

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Distribution and regulation of the prohormone convertases PC1 and PC2 in the rat pituitary

21 January 2018

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Cloning and primary sequence of a mouse candidate prohormone convertase PC1 homologous to PC2, Furin, and Kex2: distinct chromosomal localization and messenger RNA distribution in brain and pituitary compared to PC2.

21 January 2018

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Intracellular targeting and structural conservation of a prohormone-processing endoprotease.

21 January 2018

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Biogenesis of storage granules and vesicles

21 January 2018

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Prohormone-converting enzymes: regulation and evaluation of function using antisense RNA.

21 January 2018

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21 January 2018

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Cellular localization of proglucagon/glucagon-like peptide I messenger RNAs in rat brain

21 January 2018

1 reference

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Proglucagon processing similar to normal islets in pancreatic alpha-like cell line derived from transgenic mouse tumor

21 January 2018

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Immunological detection of prohormone convertases in two different proglucagon processing cell lines

21 January 2018

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Levels of the conversion endoproteases PC1 (PC3) and PC2 distinguish between insulin-producing pancreatic islet beta cells and non-beta cells

21 January 2018

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Proglucagon is processed to glucagon by prohormone convertase PC2 in alpha TC1-6 cells

21 January 2018

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Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

21 January 2018

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Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase

21 January 2018

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Ontogeny of the prohormone convertases PC1 and PC2 in the mouse hypophysis and their colocalization with corticotropin and alpha-melanotropin

21 January 2018

1 reference

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Developmental expression of the prohormone convertases PC1 and PC2 in mouse pancreatic islets.

21 January 2018

1 reference

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Intraorganellar calcium and pH control proinsulin cleavage in the pancreatic beta cell via two distinct site-specific endopeptidases

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.270.17.10136

Proinsulin processing by the subtilisin-related proprotein convertases furin, PC2, and PC3

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.270.17.10136

pH-independent and -dependent cleavage of proinsulin in the same secretory vesicle

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.270.17.10136

The neuroendocrine polypeptide 7B2 is an endogenous inhibitor of prohormone convertase PC2

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.270.17.10136

21 January 2018

Identifiers

DOI

10.1074/JBC.270.17.10136

1 reference

8 February 2018

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8 February 2018