Characterization of zebrafish smad1, smad2 and smad5: the amino-terminus of smad1 and smad5 is required for specific function in the embryo. (Q47919138)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10525190%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

title

Characterization of zebrafish smad1, smad2 and smad5: the amino-terminus of smad1 and smad5 is required for specific function in the embryo (English)

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1 November 2019

2

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1 November 2019

Sepand Rastegar

3

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1 November 2019

author name string

F Müller

1

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1 November 2019

N Fischer

4

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1 November 2019

W Knöchel

5

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1 November 2019

U Strähle

6

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1 November 2019

publication date

1 October 1999

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Mechanisms of Development

1 November 2019

published in

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1 November 2019

volume

88

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1 November 2019

issue

1

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1 November 2019

page(s)

73-88

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A novel mesoderm inducer, Madr2, functions in the activin signal transduction pathway

1 November 2019

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Smad4 and FAST-1 in the assembly of activin-responsive factor

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Direct binding of Smad3 and Smad4 to critical TGF beta-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene

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Smads: transcriptional activators of TGF-beta responses

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Intraembryonic hematopoietic cell migration during vertebrate development

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Zebrafish nodal-related 2 encodes an early mesendodermal inducer signaling from the extraembryonic yolk syncytial layer

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Zebrafish organizer development and germ-layer formation require nodal-related signals.

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Studies with a Xenopus BMP receptor suggest that ventral mesoderm-inducing signals override dorsal signals in vivo

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Xenopus Mad proteins transduce distinct subsets of signals for the TGF beta superfamily.

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The EGF-CFC protein one-eyed pinhead is essential for nodal signaling

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Mutations increasing autoinhibition inactivate tumour suppressors Smad2 and Smad4.

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7 January 2021

Smad6 inhibits BMP/Smad1 signaling by specifically competing with the Smad4 tumor suppressor

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7 January 2021

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7 January 2021

TGF-beta signalling from cell membrane to nucleus through SMAD proteins

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7 January 2021

Bone morphogenetic proteins in development

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Smad6 inhibits signalling by the TGF-beta superfamily.

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7 January 2021

Drosophila Mad binds to DNA and directly mediates activation of vestigial by Decapentaplegic

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7 January 2021

The TGF-beta superfamily: new members, new receptors, and new genetic tests of function in different organisms

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7 January 2021

A functionally conserved homolog of the Drosophila segment polarity gene hh is expressed in tissues with polarizing activity in zebrafish embryos

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7 January 2021

Opposing BMP and EGF signalling pathways converge on the TGF-beta family mediator Smad1

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7 January 2021

The TGF-beta family mediator Smad1 is phosphorylated directly and activated functionally by the BMP receptor kinase

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7 January 2021

Smad2 and Smad3 positively and negatively regulate TGF beta-dependent transcription through the forkhead DNA-binding protein FAST2

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7 January 2021

Partnership between DPC4 and SMAD proteins in TGF-beta signalling pathways.

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7 January 2021

Dorsal differentiation of neural plate cells induced by BMP-mediated signals from epidermal ectoderm

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7 January 2021

A human Mad protein acting as a BMP-regulated transcriptional activator

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7 January 2021

Dual role of the Smad4/DPC4 tumor suppressor in TGFbeta-inducible transcriptional complexes

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7 January 2021

MADR2 is a substrate of the TGFbeta receptor and its phosphorylation is required for nuclear accumulation and signaling

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7 January 2021

Specific activation of Smad1 signaling pathways by the BMP7 type I receptor, ALK2

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7 January 2021

A truncated bone morphogenetic protein 4 receptor alters the fate of ventral mesoderm to dorsal mesoderm: roles of animal pole tissue in the development of ventral mesoderm

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7 January 2021

TGF-beta signalling through the Smad pathway

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7 January 2021

The transforming growth factor-beta family

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7 January 2021

TGF-beta signal transduction

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7 January 2021

The C-terminal domain of Mad-like signal transducers is sufficient for biological activity in the Xenopus embryo and transcriptional activation.

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7 January 2021

Identification of Smad7, a TGFbeta-inducible antagonist of TGF-beta signalling

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7 January 2021

A graded response to BMP-4 spatially coordinates patterning of the mesoderm and ectoderm in the zebrafish.

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7 January 2021

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7 January 2021

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7 January 2021

Cloning of the zebrafish krox-20 gene (krx-20) and its expression during hindbrain development

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7 January 2021

Transcriptional regulation of Xvent homeobox genes.

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7 January 2021

Zebrafish nodal-related genes are implicated in axial patterning and establishing left-right asymmetry

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7 January 2021

cyclops encodes a nodal-related factor involved in midline signaling

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7 January 2021

Floor plate and motor neuron induction by vhh-1, a vertebrate homolog of hedgehog expressed by the notochord

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7 January 2021

Induction of the zebrafish ventral brain and floorplate requires cyclops/nodal signalling.

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7 January 2021

Caenorhabditis elegans genes sma-2, sma-3, and sma-4 define a conserved family of transforming growth factor beta pathway components

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7 January 2021

The zebrafish organizer requires chordino

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7 January 2021

Transcriptional activating activity of Smad4: roles of SMAD hetero-oligomerization and enhancement by an associating transactivator

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7 January 2021

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7 January 2021

Axial, a zebrafish gene expressed along the developing body axis, shows altered expression in cyclops mutant embryos

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7 January 2021

Smad5 induces ventral fates in Xenopus embryo

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7 January 2021

Expression of achaete-scute homolog 3 in Xenopus embryos converts ectodermal cells to a neural fate

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7 January 2021

SMAD3/4-dependent transcriptional activation of the human type VII collagen gene (COL7A1) promoter by transforming growth factor beta.

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7 January 2021

Bone morphogenetic protein-4 is required for mesoderm formation and patterning in the mouse

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7 January 2021

TGF-beta receptors and signalling mechanisms

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7 January 2021

Alternatively spliced variant of Smad2 lacking exon 3. Comparison with wild-type Smad2 and Smad3.

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7 January 2021

Human Smad3 and Smad4 are sequence-specific transcription activators

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7 January 2021

The tumor suppressor Smad4/DPC 4 as a central mediator of Smad function

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7 January 2021

Nodal is a novel TGF-beta-like gene expressed in the mouse node during gastrulation

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7 January 2021

10.1016/S0925-4773(99)00173-2

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10525190%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

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