C-terminal BRE overexpression in 11q23-rearranged and t(8;16) acute myeloid leukemia is caused by intragenic transcription initiation. (Q47857157)

6 February 2018

title

C-terminal BRE overexpression in 11q23-rearranged and t(8;16) acute myeloid leukemia is caused by intragenic transcription initiation. (English)

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6 February 2018

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acute myeloid leukemia

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18

T Haferlach

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6 February 2018

A E Marneth

1

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K H M Prange

2

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A S A Al Hinai

3

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S M Bergevoet

4

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N Tesi

5

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E M Janssen-Megens

6

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B Kim

7

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N Sharifi

8

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M L Yaspo

9

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J Kuster

10

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M A Sanders

11

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E C G Stoetman

12

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J Knijnenburg

13

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T C J M Arentsen-Peters

14

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C M Zwaan

15

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H G Stunnenberg

16

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6 February 2018

M M van den Heuvel-Eibrink

17

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6 February 2018

M Fornerod

19

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6 February 2018

J H Jansen

20

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P J M Valk

21

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B A van der Reijden

22

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6 February 2018

J H A Martens

23

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6 February 2018

publication date

5 September 2017

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6 February 2018

published in

Leukemia

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6 February 2018

https://scigraph.springernature.com/pub.10.1038/leu.2017.280

exact match

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cites work

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A single oncogenic enhancer rearrangement causes concomitant EVI1 and GATA2 deregulation in leukemia

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A remote GATA2 hematopoietic enhancer drives leukemogenesis in inv(3)(q21;q26) by activating EVI1 expression

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Repression of RUNX1 activity by EVI1: a new role of EVI1 in leukemogenesis

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Point mutations in two EVI1 Zn fingers abolish EVI1-GATA1 interaction and allow erythroid differentiation of murine bone marrow cells.

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EVI1 Impairs myelopoiesis by deregulation of PU.1 function

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Favorable impact of the t(9;11) in childhood acute myeloid leukemia

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Anti-apoptotic protein BRE/BRCC45 attenuates apoptosis through maintaining the expression of caspase inhibitor XIAP in mouse Lewis lung carcinoma D122 cells

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Regulation of BRCC, a holoenzyme complex containing BRCA1 and BRCA2, by a signalosome-like subunit and its role in DNA repair

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Differential expression of a novel gene BRE (TNFRSF1A modulator/BRCC45) in response to stress and biological signals.

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BRE plays an essential role in preventing replicative and DNA damage-induced premature senescence

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MERIT40 facilitates BRCA1 localization and DNA damage repair

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Three-Dimensional Architecture of the Human BRCA1-A Histone Deubiquitinase Core Complex

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The deubiquitinating enzyme complex BRISC is required for proper mitotic spindle assembly in mammalian cells

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Prognostically useful gene-expression profiles in acute myeloid leukemia.

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AML with translocation t(8;16)(p11;p13) demonstrates unique cytomorphological, cytogenetic, molecular and prognostic features.

21 January 2018

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Pediatric acute myeloid leukemia with t(8;16)(p11;p13), a distinct clinical and biological entity: a collaborative study by the International-Berlin-Frankfurt-Munster AML-study group.

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Double CEBPA mutations, but not single CEBPA mutations, define a subgroup of acute myeloid leukemia with a distinctive gene expression profile that is uniquely associated with a favorable outcome

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MLL-AF9 and MLL-AF4 oncofusion proteins bind a distinct enhancer repertoire and target the RUNX1 program in 11q23 acute myeloid leukemia

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Morgana acts as an oncosuppressor in chronic myeloid leukemia.

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Identification of genes that synergize with Cbfb-MYH11 in the pathogenesis of acute myeloid leukemia

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Plag1 and Plagl2 are oncogenes that induce acute myeloid leukemia in cooperation with Cbfb-MYH11

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Systematic Classification of Mixed-Lineage Leukemia Fusion Partners Predicts Additional Cancer Pathways

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MOZ and MOZ-CBP cooperate with NF-kappaB to activate transcription from NF-kappaB-dependent promoters.

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Crosstalk between leukemia-associated proteins MOZ and MLL regulates HOX gene expression in human cord blood CD34+ cells

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21 January 2018

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Activation of AML1-mediated transcription by MOZ and inhibition by the MOZ-CBP fusion protein

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ABRO1 suppresses tumourigenesis and regulates the DNA damage response by stabilizing p53.

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BRE is an antiapoptotic protein in vivo and overexpressed in human hepatocellular carcinoma.

21 January 2018

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Comparative proteomic analysis reveals differentially expressed proteins regulated by a potential tumor promoter, BRE, in human esophageal carcinoma cells

21 January 2018

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Comprehensive Pan-Genomic Characterization of Adrenocortical Carcinoma

21 January 2018

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Expression of the BRCA1 complex member BRE predicts disease free survival in breast cancer.

21 January 2018

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High BRE expression predicts favorable outcome in adult acute myeloid leukemia, in particular among MLL-AF9-positive patients

21 January 2018

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High BRE expression in pediatric MLL-rearranged AML is associated with favorable outcome

21 January 2018

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21 January 2018

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7 January 2021

Attitudes of terminally ill cancer patients about euthanasia and assisted suicide: predominance of psychosocial determinants and beliefs over symptom distress and subsequent survival.

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https://api.crossref.org/works/10.1038%2FLEU.2017.280

7 January 2021

Evi-1 is a transcriptional target of mixed-lineage leukemia oncoproteins in hematopoietic stem cells

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https://api.crossref.org/works/10.1038%2FLEU.2017.280

7 January 2021

Improved classification of MLL-AF9-positive acute myeloid leukemia patients based on BRE and EVI1 expression

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https://api.crossref.org/works/10.1038%2FLEU.2017.280

7 January 2021

BRCC3 mutations in myeloid neoplasms

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28871137

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1038/LEU.2017.280

1 reference

6 February 2018

PubMed ID

28871137

1 reference

6 February 2018