Review: Aberrant EVI1 expression in acute myeloid leukaemia (Q38686515)

5 September 2017

Review: Aberrant EVI1 expression in acute myeloid leukaemia (English)

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5 September 2017

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Adil A Hinai

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PubMed ID

26729571

5 September 2017

Peter J M Valk

series ordinal

2

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PubMed ID

26729571

5 September 2017

language of work or name

English

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publication date

5 January 2016

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British Journal of Haematology

5 September 2017

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5 September 2017

172

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5 September 2017

6

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5 September 2017

870-878

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Integrated genome-wide genotyping and gene expression profiling reveals BCL11B as a putative oncogene in acute myeloid leukemia with 14q32 aberrations

5 September 2017

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Clinical implications of novel mutations in epigenetic modifiers in AML.

21 January 2018

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Regulation of the expression of the oncogene EVI1 through the use of alternative mRNA 5'-ends.

21 January 2018

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EVI1 overexpression in distinct subtypes of pediatric acute myeloid leukemia

21 January 2018

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High EVI1 expression predicts poor survival in acute myeloid leukemia: a study of 319 de novo AML patients

21 January 2018

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The Evi-1 proto-oncogene encodes a transcriptional repressor activity associated with transformation

21 January 2018

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EVI1 is critical for the pathogenesis of a subset of MLL-AF9-rearranged AMLs.

21 January 2018

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EVI1 induces myelodysplastic syndrome in mice

21 January 2018

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Both AML1 and EVI1 oncogenic components are required for the cooperation of AML1/MDS1/EVI1 with BCR/ABL in the induction of acute myelogenous leukemia in mice

21 January 2018

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3q26/EVI1 rearrangements in myeloid hemopathies: a cytogenetic review

21 January 2018

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Four of the seven zinc fingers of the Evi-1 myeloid-transforming gene are required for sequence-specific binding to GA(C/T)AAGA(T/C)AAGATAA.

21 January 2018

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Diagnosis and management of acute myeloid leukemia in adults: recommendations from an international expert panel, on behalf of the European LeukemiaNet

21 January 2018

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Intergenic splicing of MDS1 and EVI1 occurs in normal tissues as well as in myeloid leukemia and produces a new member of the PR domain family

21 January 2018

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Global Identification of EVI1 Target Genes in Acute Myeloid Leukemia

21 January 2018

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Evi-1 is a critical regulator for hematopoietic stem cells and transformed leukemic cells.

21 January 2018

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Deregulated expression of EVI1 defines a poor prognostic subset of MLL-rearranged acute myeloid leukemias: a study of the German-Austrian Acute Myeloid Leukemia Study Group and the Dutch-Belgian-Swiss HOVON/SAKK Cooperative Group

21 January 2018

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A single oncogenic enhancer rearrangement causes concomitant EVI1 and GATA2 deregulation in leukemia

21 January 2018

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Mutational spectrum of myeloid malignancies with inv(3)/t(3;3) reveals a predominant involvement of RAS/RTK signaling pathways

21 January 2018

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High EVI1 expression is associated with MLL rearrangements and predicts decreased survival in paediatric acute myeloid leukaemia: a report from the children's oncology group

21 January 2018

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GATA2 haploinsufficiency caused by mutations in a conserved intronic element leads to MonoMAC syndrome

21 January 2018

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The PR domain of the Rb-binding zinc finger protein RIZ1 is a protein binding interface and is related to the SET domain functioning in chromatin-mediated gene expression.

21 January 2018

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Trib1 and Evi1 cooperate with Hoxa and Meis1 in myeloid leukemogenesis.

21 January 2018

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High expression of EVI1 and MEL1 is a compelling poor prognostic marker of pediatric AML.

21 January 2018

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Cytogenetic and molecular genetic evolution of chronic myeloid leukemia.

21 January 2018

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Ecotropic viral integration site 1, stem cell self-renewal and leukemogenesis

21 January 2018

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Evi-1 ZF1 DNA binding activity and a second distinct transcriptional repressor region are both required for optimal transformation of Rat1 fibroblasts

21 January 2018

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Loss of erythropoietin responsiveness in erythroid progenitors due to expression of the Evi-1 myeloid-transforming gene

21 January 2018

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Cell of origin determines clinically relevant subtypes of MLL-rearranged AML

21 January 2018

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Significant increase of self-renewal in hematopoietic cells after forced expression of EVI1.

21 January 2018

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EVI1-rearranged acute myeloid leukemias are characterized by distinct molecular alterations

21 January 2018

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Conditional Gata2 inactivation results in HSC loss and lymphatic mispatterning

21 January 2018

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GATA-2 plays two functionally distinct roles during the ontogeny of hematopoietic stem cells

21 January 2018

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High EVI1 levels predict adverse outcome in acute myeloid leukemia: prevalence of EVI1 overexpression and chromosome 3q26 abnormalities underestimated.

21 January 2018

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EVI1 overexpression is a poor prognostic factor in pediatric patients with mixed lineage leukemia-AF9 rearranged acute myeloid leukemia.

21 January 2018

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Retroviral activation of a novel gene encoding a zinc finger protein in IL-3-dependent myeloid leukemia cell lines

21 January 2018

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Expression of the Evi-1 zinc finger gene in 32Dc13 myeloid cells blocks granulocytic differentiation in response to granulocyte colony-stimulating factor

21 January 2018

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Identification of a common ecotropic viral integration site, Evi-1, in the DNA of AKXD murine myeloid tumors

21 January 2018

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Evi-1 transforming and repressor activities are mediated by CtBP co-repressor proteins

21 January 2018

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Zinc fingers 1-7 of EVI1 fail to bind to the GATA motif by itself but require the core site GACAAGATA for binding

21 January 2018

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The evolving molecular genetic landscape in acute myeloid leukaemia

21 January 2018

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Pbx1 is a downstream target of Evi-1 in hematopoietic stem/progenitors and leukemic cells

21 January 2018

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Acetylation of lysine 564 adjacent to the C-terminal binding protein-binding motif in EVI1 is crucial for transcriptional activation of GATA2.

21 January 2018

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The leukemia-associated gene MDS1/EVI1 is a new type of GATA-binding transactivator

21 January 2018

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Prognostically useful gene-expression profiles in acute myeloid leukemia.

21 January 2018

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The 2008 revision of the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia: rationale and important changes

21 January 2018

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Amplification of EVI1 on cytogenetically cryptic double minutes as new mechanism for increased expression of EVI1.

21 January 2018

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NBA1, a new player in the Brca1 A complex, is required for DNA damage resistance and checkpoint control

21 January 2018

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Phosphorylation of the leukemic oncoprotein EVI1 on serine 196 modulates DNA binding, transcriptional repression and transforming ability

21 January 2018

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A remote GATA2 hematopoietic enhancer drives leukemogenesis in inv(3)(q21;q26) by activating EVI1 expression

21 January 2018

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Evi1 represses PTEN expression and activates PI3K/AKT/mTOR via interactions with polycomb proteins.

21 January 2018

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Oncogenic transcription factor Evi1 regulates hematopoietic stem cell proliferation through GATA-2 expression

21 January 2018

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High BRE expression predicts favorable outcome in adult acute myeloid leukemia, in particular among MLL-AF9-positive patients

21 January 2018

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High BRE expression in pediatric MLL-rearranged AML is associated with favorable outcome

21 January 2018

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21 January 2018

Identifiers

DOI

10.1111/BJH.13898

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5 September 2017

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PubMed ID

26729571