Pten deletion in adult hippocampal neural stem/progenitor cells causes cellular abnormalities and alters neurogenesis. (Q47843523)

http://europepmc.org/abstract/MED/22539849

6 February 2018

title

Pten deletion in adult hippocampal neural stem/progenitor cells causes cellular abnormalities and alters neurogenesis (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6703621&resulttype=core&format=json

11 May 2020

1 reference

Anahita Amiri

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6703621&resulttype=core&format=json

11 May 2020

Woosung Cho

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6703621&resulttype=core&format=json

11 May 2020

Jing Zhou

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6703621&resulttype=core&format=json

11 May 2020

Shari G Birnbaum

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6703621&resulttype=core&format=json

11 May 2020

Christopher M Sinton

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6703621&resulttype=core&format=json

11 May 2020

Renée M McKay

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6703621&resulttype=core&format=json

11 May 2020

Luis F Parada

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6703621&resulttype=core&format=json

11 May 2020

language of work or name

English

0 references

publication date

1 April 2012

1 reference

http://europepmc.org/abstract/MED/22539849

6 February 2018

published in

Journal of Neuroscience

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6703621&resulttype=core&format=json

11 May 2020

volume

32

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6703621&resulttype=core&format=json

11 May 2020

page(s)

5880-5890

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6703621&resulttype=core&format=json

11 May 2020

issue

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6703621&resulttype=core&format=json

describes a project that uses

11 May 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6703621/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Growth factors regulate the survival and fate of cells derived from human neurospheres.

1 reference

12 December 2020

The Hedgehog and Wnt signalling pathways in cancer

1 reference

12 December 2020

PTEN mutation in a family with Cowden syndrome and autism

1 reference

12 December 2020

Negative regulation of neural stem/progenitor cell proliferation by the Pten tumor suppressor gene in vivo.

1 reference

12 December 2020

Deletion of Pten in mouse brain causes seizures, ataxia and defects in soma size resembling Lhermitte-Duclos disease.

1 reference

12 December 2020

Pten regulates neuronal soma size: a mouse model of Lhermitte-Duclos disease.

1 reference

12 December 2020

PTEN is essential for cell migration but not for fate determination and tumourigenesis in the cerebellum

1 reference

12 December 2020

Raf and akt mediate distinct aspects of sensory axon growth

1 reference

12 December 2020

BMP2 exposure results in decreased PTEN protein degradation and increased PTEN levels

1 reference

12 December 2020

Tuberous sclerosis complex gene products, Tuberin and Hamartin, control mTOR signaling by acting as a GTPase-activating protein complex toward Rheb

1 reference

12 December 2020

PTEN: one gene, many syndromes

1 reference

12 December 2020

mTor is required for hypertrophy of Pten-deficient neuronal soma in vivo

1 reference

12 December 2020

Pten loss causes hypertrophy and increased proliferation of astrocytes in vivo

1 reference

12 December 2020

Autism and tuberous sclerosis

1 reference

12 December 2020

Both the establishment and the maintenance of neuronal polarity require active mechanisms: critical roles of GSK-3beta and its upstream regulators

1 reference

12 December 2020

GSK-3beta regulates phosphorylation of CRMP-2 and neuronal polarity.

1 reference

12 December 2020

Designing mouse behavioral tasks relevant to autistic-like behaviors

1 reference

12 December 2020

Neuroanatomic observations of the brain in autism: a review and future directions

1 reference

12 December 2020

Subset of individuals with autism spectrum disorders and extreme macrocephaly associated with germline PTEN tumour suppressor gene mutations

1 reference

12 December 2020

PTEN deletion in Bergmann glia leads to premature differentiation and affects laminar organization

1 reference

12 December 2020

Bmi-1 promotes neural stem cell self-renewal and neural development but not mouse growth and survival by repressing the p16Ink4a and p19Arf senescence pathways

1 reference

12 December 2020

PTEN negatively regulates neural stem cell self-renewal by modulating G0-G1 cell cycle entry

1 reference

12 December 2020

Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells

1 reference

12 December 2020

PTEN maintains haematopoietic stem cells and acts in lineage choice and leukaemia prevention

1 reference

12 December 2020

Pten regulates neuronal arborization and social interaction in mice

1 reference

12 December 2020

Ablation of hippocampal neurogenesis impairs contextual fear conditioning and synaptic plasticity in the dentate gyrus

1 reference

12 December 2020

Mutation screening of the PTEN gene in patients with autism spectrum disorders and macrocephaly

1 reference

12 December 2020

Enriched monolayer precursor cell cultures from micro-dissected adult mouse dentate gyrus yield functional granule cell-like neurons.

1 reference

12 December 2020

A seizure-prone phenotype is associated with altered free-running rhythm in Pten mutant mice

1 reference

12 December 2020

A role for adult TLX-positive neural stem cells in learning and behaviour

1 reference

12 December 2020

Mechanisms and functional implications of adult neurogenesis

1 reference

12 December 2020

Spatial relational memory requires hippocampal adult neurogenesis

1 reference

12 December 2020

TrkB regulates hippocampal neurogenesis and governs sensitivity to antidepressive treatment

1 reference

12 December 2020

Roles of continuous neurogenesis in the structural and functional integrity of the adult forebrain.

1 reference

12 December 2020

PTEN signaling in brain: neuropathology and tumorigenesis.

1 reference

12 December 2020

Pavlov's moth: olfactory learning and spike timing-dependent plasticity.

1 reference

12 December 2020

Inducible site-specific recombination in neural stem/progenitor cells

1 reference

12 December 2020

Dentate gyrus-specific knockdown of adult neurogenesis impairs spatial and object recognition memory in adult rats

1 reference

12 December 2020

Pharmacological inhibition of mTORC1 suppresses anatomical, cellular, and behavioral abnormalities in neural-specific Pten knock-out mice

1 reference

12 December 2020

Pten deletion in adult neural stem/progenitor cells enhances constitutive neurogenesis.

1 reference

12 December 2020

The prevalence of PTEN mutations in a clinical pediatric cohort with autism spectrum disorders, developmental delay, and macrocephaly.

1 reference

12 December 2020

mTORC1 signaling governs hematopoietic stem cell quiescence

1 reference

12 December 2020

Neural stem cells in the developing and adult brains

1 reference

12 December 2020

A functional role for adult hippocampal neurogenesis in spatial pattern separation

1 reference

12 December 2020

Validation of a novel method to interrupt sleep in the mouse.

1 reference

12 December 2020

mTOR mediates Wnt-induced epidermal stem cell exhaustion and aging.

1 reference

12 December 2020

Connecting genes to brain in the autism spectrum disorders

1 reference

12 December 2020

Behavioural phenotyping assays for mouse models of autism

1 reference

12 December 2020

GSK3 signalling in neural development

1 reference

12 December 2020

In vivo clonal analysis reveals self-renewing and multipotent adult neural stem cell characteristics

1 reference

12 December 2020

Tsc1 mutant neural stem/progenitor cells exhibit migration deficits and give rise to subependymal lesions in the lateral ventricle

1 reference

12 December 2020

Affiliative behavior requires juvenile, but not adult neurogenesis

1 reference

12 December 2020

A Golgi study of cell types in the hilar region of the hippocampus in the rat.

1 reference

12 December 2020

Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

1 reference

12 December 2020

PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer

1 reference

12 December 2020

The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate

1 reference

12 December 2020

Adult neurogenesis: from canaries to the clinic

1 reference

12 December 2020

High cancer susceptibility and embryonic lethality associated with mutation of the PTEN tumor suppressor gene in mice

1 reference

12 December 2020

Generalized lacZ expression with the ROSA26 Cre reporter strain

1 reference

12 December 2020

10.1523/JNEUROSCI.5462-11.2012

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6703621&resulttype=core&format=json

11 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6703621&resulttype=core&format=json

11 May 2020

1 reference