Genomics-Driven Precision Medicine for Advanced Pancreatic Cancer - Early Results from the COMPASS Trial. (Q47232401)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29288237%20AND%20SRC:MED&resulttype=core&format=json

8 April 2020

title

Genomics-Driven Precision Medicine for Advanced Pancreatic Cancer: Early Results from the COMPASS Trial (English)

1 reference

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8 April 2020

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14

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8 April 2020

Richard A Moffitt

24

1 reference

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8 April 2020

Paul M Krzyzanowski

27

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8 April 2020

33

Steven Gallinger

1 reference

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8 April 2020

author name string

Sandra E Fischer

2

1 reference

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8 April 2020

Robert E Denroche

3

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8 April 2020

Gun-Ho Jang

4

1 reference

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8 April 2020

Anna Dodd

5

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8 April 2020

Sean Creighton

6

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8 April 2020

Bernadette Southwood

7

1 reference

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8 April 2020

Sheng-Ben Liang

8

1 reference

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8 April 2020

Dianne Chadwick

9

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8 April 2020

Amy Zhang

10

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8 April 2020

Grainne M O'Kane

11

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8 April 2020

Shari Moura

13

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8 April 2020

Jessica K Miller

15

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8 April 2020

Faridah Mbabaali

16

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8 April 2020

Danielle Pasternack

17

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8 April 2020

Ilinca M Lungu

18

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8 April 2020

John M S Bartlett

19

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8 April 2020

Sangeet Ghai

20

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8 April 2020

Mathieu Lemire

21

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8 April 2020

Spring Holter

22

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8 April 2020

Ashton A Connor

23

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8 April 2020

Jen Jen Yeh

25

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8 April 2020

Lee Timms

26

1 reference

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8 April 2020

Faiyaz Notta

30

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8 April 2020

Julie M Wilson

31

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8 April 2020

Malcolm J Moore

32

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8 April 2020

Jennifer J Knox

34

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8 April 2020

Kyaw L Aung

1

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8 April 2020

Hamzeh Albaba

12

1 reference

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8 April 2020

Neesha Dhani

28

1 reference

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8 April 2020

David Hedley

29

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8 April 2020

language of work or name

English

0 references

publication date

29 December 2017

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8 April 2020

published in

Clinical Cancer Research

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8 April 2020

volume

24

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8 April 2020

page(s)

1344-1354

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8 April 2020

issue

6

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Integrated Genomic Characterization of Pancreatic Ductal Adenocarcinoma.

8 April 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5968824

Real-Time Genomic Profiling of Pancreatic Ductal Adenocarcinoma: Potential Actionability and Correlation with Clinical Phenotype.

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5968824

Next generation sequencing of pancreatic ductal adenocarcinoma: right or wrong?

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5968824

Pancreatic Cancer Genomes: Implications for Clinical Management and Therapeutic Development.

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5968824

HRDetect is a predictor of BRCA1 and BRCA2 deficiency based on mutational signatures.

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5968824

A somatic-mutational process recurrently duplicates germline susceptibility loci and tissue-specific super-enhancers in breast cancers

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5968824

ATR inhibitors as a synthetic lethal therapy for tumours deficient in ARID1A.

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5968824

Activity of the novel polo-like kinase 4 inhibitor CFI-400945 in pancreatic cancer patient-derived xenografts

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5968824

Association of Distinct Mutational Signatures With Correlates of Increased Immune Activity in Pancreatic Ductal Adenocarcinoma

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5968824

A renewed model of pancreatic cancer evolution based on genomic rearrangement patterns

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5968824

Pancreatic cancer biology and genetics from an evolutionary perspective

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5968824

GATA6 regulates EMT and tumour dissemination, and is a marker of response to adjuvant chemotherapy in pancreatic cancer

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5968824

Metastatic Pancreatic Cancer: American Society of Clinical Oncology Clinical Practice Guideline

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5968824

Landscape of somatic mutations in 560 breast cancer whole-genome sequences

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5968824

The tandem duplicator phenotype as a distinct genomic configuration in cancer

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5968824

Genomic analyses identify molecular subtypes of pancreatic cancer

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5968824

The Molecular Signatures Database (MSigDB) hallmark gene set collection

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5968824

The Reactome pathway Knowledgebase

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5968824

Targeting Mitosis in Cancer: Emerging Strategies

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5968824

The consensus molecular subtypes of colorectal cancer

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5968824

Genetic Diversity of Pancreatic Ductal Adenocarcinoma and Opportunities for Precision Medicine

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5968824

Virtual microdissection identifies distinct tumor- and stroma-specific subtypes of pancreatic ductal adenocarcinoma.

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5968824

ARID1A Deficiency Impairs the DNA Damage Checkpoint and Sensitizes Cells to PARP Inhibitors

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5968824

Germline BRCA Mutations in a Large Clinic-Based Cohort of Patients With Pancreatic Adenocarcinoma.

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5968824

Precision Medicine for Advanced Pancreas Cancer: The Individualized Molecular Pancreatic Cancer Therapy (IMPaCT) Trial

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5968824

Molecular analysis of gastric cancer identifies subtypes associated with distinct clinical outcomes.

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5968824

Whole genomes redefine the mutational landscape of pancreatic cancer

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5968824

Synthetic lethality by targeting EZH2 methyltransferase activity in ARID1A-mutated cancers

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5968824

CDK4/6 inhibitors have potent activity in combination with pathway selective therapeutic agents in models of pancreatic cancer

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5968824

Identification of distinct basal and luminal subtypes of muscle-invasive bladder cancer with different sensitivities to frontline chemotherapy

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5968824

Annotating cancer variants and anti-cancer therapeutics in reactome

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5968824

Increased survival in pancreatic cancer with nab-paclitaxel plus gemcitabine

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5968824

Evolution and dynamics of pancreatic cancer progression

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5968824

Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5968824

Comprehensive molecular portraits of human breast tumours

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5968824

FOLFIRINOX versus gemcitabine for metastatic pancreatic cancer

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5968824

Molecular signatures database (MSigDB) 3.0.

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5968824

Subtypes of pancreatic ductal adenocarcinoma and their differing responses to therapy

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5968824

Distant metastasis occurs late during the genetic evolution of pancreatic cancer

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5968824

The patterns and dynamics of genomic instability in metastatic pancreatic cancer

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5968824

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5968824

PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5968824

KEGG: kyoto encyclopedia of genes and genomes

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5968824

2 November 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/29288237

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1158/1078-0432.CCR-17-2994

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29288237%20AND%20SRC:MED&resulttype=core&format=json

8 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29288237%20AND%20SRC:MED&resulttype=core&format=json

8 April 2020

1 reference