Iridoids and Other Monoterpenes in the Alzheimer's Brain: Recent Development and Future Prospects (Q47216965)

11 January 2018

5 references

25 April 2019

7 November 2019

28 August 2020

26 January 2021

8 October 2022

Iridoids and Other Monoterpenes in the Alzheimer's Brain: Recent Development and Future Prospects (English)

1 reference

11 January 2018

cyclopentane monoterpenoid

3 references

25 April 2019

7 November 2019

28 August 2020

1 reference

7 November 2019

1 reference

28 August 2020

neuroprotective agent

1 reference

26 January 2021

1

Solomon Habtemariam

1 reference

11 January 2018

language of work or name

English

0 references

publication date

7 January 2018

6 references

11 January 2018

25 April 2019

7 November 2019

28 August 2020

26 January 2021

8 October 2022

5 references

11 January 2018

25 April 2019

7 November 2019

28 August 2020

26 January 2021

23

1 reference

11 January 2018

issue

1

1 reference

11 January 2018

Creative Commons Attribution

copyright license

5 references

25 April 2019

7 November 2019

28 August 2020

26 January 2021

8 October 2022

0 references

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ScienceSource

0 references

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21 January 2018

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21 January 2018

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21 January 2018

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Catalpol regulates cholinergic nerve system function through effect on choline acetyl-transferase not M receptor affinity.

21 January 2018

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Protective effects of catalpol against H2O2-induced oxidative stress in astrocytes primary cultures

21 January 2018

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Borneol alleviates oxidative stress via upregulation of Nrf2 and Bcl-2 in SH-SY5Y cells

21 January 2018

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1,8-cineole (eucalyptol) mitigates inflammation in amyloid Beta toxicated PC12 cells: relevance to Alzheimer's disease.

21 January 2018

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Genipin inhibits the inflammatory response of rat brain microglial cells.

21 January 2018

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Genipin suppresses A23187-induced cytotoxicity in neuro2a cells

21 January 2018

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Geniposide Protects Primary Cortical Neurons against Oligomeric Aβ1-42-Induced Neurotoxicity through a Mitochondrial Pathway

21 January 2018

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Leptin signaling plays a critical role in the geniposide-induced decrease of tau phosphorylation

21 January 2018

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Cell Signaling Mechanisms by which Geniposide Regulates Insulin- Degrading Enzyme Expression in Primary Cortical Neurons.

21 January 2018

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Geniposide attenuates the level of Aβ1-42 via enhancing leptin signaling in cellular and APP/PS1 transgenic mice.

21 January 2018

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Neuroprotective effects of geniposide in SH-SY5Y cells and primary hippocampal neurons exposed to Aβ42.

21 January 2018

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21 January 2018

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Neuroprotection of geniposide against hydrogen peroxide induced PC12 cells injury: involvement of PI3 kinase signal pathway

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Geniposide, a novel agonist for GLP-1 receptor, prevents PC12 cells from oxidative damage via MAP kinase pathway.

21 January 2018

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21 January 2018

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Kinetics and molecular docking studies of loganin, morroniside and 7-O-galloyl-D-sedoheptulose derived from Corni fructus as cholinesterase and β-secretase 1 inhibitors

21 January 2018

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21 January 2018

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21 January 2018

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Myrtenal inhibits acetylcholinesterase, a known Alzheimer target

21 January 2018

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Synthesis, anticholinesterase activity and molecular modeling study of novel carbamate-substituted thymol/carvacrol derivatives

21 January 2018

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Paeoniflorin inhibition of 6-hydroxydopamine-induced apoptosis in PC12 cells via suppressing reactive oxygen species-mediated PKCδ/NF-κB pathway

21 January 2018

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21 January 2018

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Carvacrol alleviates cerebral edema by modulating AQP4 expression after intracerebral hemorrhage in mice.

21 January 2018

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Catalpol preserves neural function and attenuates the pathology of Alzheimer's disease in mice

21 January 2018

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Catalpol improves cholinergic function and reduces inflammatory cytokines in the senescent mice induced by D-galactose

21 January 2018

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d-galactose administration induces memory loss and energy metabolism disturbance in mice: protective effects of catalpol

21 January 2018

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Further pharmacological evidence of the neuroprotective effect of catalpol from Rehmannia glutinosa

21 January 2018

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Geniposide attenuates insulin-deficiency-induced acceleration of β-amyloidosis in an APP/PS1 transgenic model of Alzheimer's disease.

21 January 2018

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Geniposide Attenuates the Phosphorylation of Tau Protein in Cellular and Insulin-deficient APP/PS1 Transgenic Mouse Model of Alzheimer's Disease.

21 January 2018

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Multi-faced neuroprotective effects of geniposide depending on the RAGE-mediated signaling in an Alzheimer mouse model.

21 January 2018

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Geniposide attenuates mitochondrial dysfunction and memory deficits in APP/PS1 transgenic mice

21 January 2018

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21 January 2018

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Geniposide decreases the level of Aβ1-42 in the hippocampus of streptozotocin-induced diabetic rats

21 January 2018

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Protective effects of linalool against amyloid beta-induced cognitive deficits and damages in mice.

21 January 2018

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Linalool reverses neuropathological and behavioral impairments in old triple transgenic Alzheimer's mice

21 January 2018

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Loganin improves learning and memory impairments induced by scopolamine in mice

21 January 2018

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Effects of oleuropein on pentylenetetrazol-induced seizures in mice: involvement of opioidergic and nitrergic systems.

21 January 2018

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Neuroprotective effects of oleuropein against cognitive dysfunction induced by colchicine in hippocampal CA1 area in rats.

21 January 2018

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Protective effect of paeoniflorin on inflammation and apoptosis in the cerebral cortex of a transgenic mouse model of Alzheimer's disease.

21 January 2018

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Paeoniflorin Atttenuates Amyloidogenesis and the Inflammatory Responses in a Transgenic Mouse Model of Alzheimer's Disease.

21 January 2018

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Peoniflorin attentuates Abeta((1-42))-mediated neurotoxicity by regulating calcium homeostasis and ameliorating oxidative stress in hippocampus of rats

21 January 2018

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Crystal structure of human aquaporin 4 at 1.8 A and its mechanism of conductance

21 January 2018

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Roles of aquaporin-4 isoforms and amino acids in square array assembly

21 January 2018

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New isoforms of rat Aquaporin-4.

21 January 2018

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Regulation of AQP4 surface expression via vesicle mobility in astrocytes

21 January 2018

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The aquaporin-4 water channel as a potential drug target in neurological disorders.

21 January 2018

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The central role of aquaporins in the pathophysiology of ischemic stroke.

21 January 2018

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Aquaporin 4: a player in cerebral edema and neuroinflammation

21 January 2018

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Aquaporin and brain diseases

21 January 2018

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Glycogen synthase kinase 3beta and Alzheimer's disease: pathophysiological and therapeutic significance

21 January 2018

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Protein Phosphorylation is a Key Mechanism in Alzheimer's Disease

21 January 2018

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Recent advances in the multitarget-directed ligands approach for the treatment of Alzheimer's disease.

21 January 2018

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New pharmacological strategies for treatment of Alzheimer's disease: focus on disease modifying drugs

21 January 2018

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Iron(II) binding to amyloid-β, the Alzheimer's peptide.

21 January 2018

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Effect of metal chelators on the aggregation of beta-amyloid peptides in the presence of copper and iron.

21 January 2018

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Free Superoxide is an Intermediate in the Production of H2O2 by Copper(I)-Aβ Peptide and O2.

21 January 2018

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Iron accumulation in Alzheimer disease is a source of redox-generated free radicals

21 January 2018

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A novel diterpene skeleton: identification of a highly aromatic, cytotoxic and antioxidant 5-methyl-10-demethyl-abietane-type diterpene from Premna serratifolia

21 January 2018

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The antidiabetic therapeutic potential of dietary polyphenols

21 January 2018

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Methyl-3-O-methyl gallate and gallic acid from the leaves of Peltiphyllum peltatum: isolation and comparative antioxidant, prooxidant, and cytotoxic effects in neuronal cells

21 January 2018

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Comparative antioxidant, prooxidant and cytotoxic activity of sigmoidin A and eriodictyol

21 January 2018

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Antidiabetic components of Cassia alata leaves: identification through α-glucosidase inhibition studies

21 January 2018

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Antihyperlipidemic components of Cassia auriculata aerial parts: identification through in vitro studies

21 January 2018

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Astrocytes: implications for neuroinflammatory pathogenesis of Alzheimer's disease

21 January 2018

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Review: Astrocytes in Alzheimer's disease and other age-associated dementias: a supporting player with a central role.

21 January 2018

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Reactive microglia in patients with senile dementia of the Alzheimer type are positive for the histocompatibility glycoprotein HLA-DR.

21 January 2018

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Microglial Priming and Alzheimer's Disease: A Possible Role for (Early) Immune Challenges and Epigenetics?

21 January 2018

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Clearance of cerebral Aβ in Alzheimer's disease: reassessing the role of microglia and monocytes.

21 January 2018

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Immune attack: the role of inflammation in Alzheimer disease.

21 January 2018

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Inhibition of Inflammation Mediated Through the Tumor Necrosis Factor α Biochemical Pathway Can Lead to Favorable Outcomes in Alzheimer Disease

21 January 2018

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Targeting Tumor Necrosis Factor Alpha for Alzheimer's Disease

21 January 2018

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Upstream regulators and downstream effectors of NF-κB in Alzheimer's disease

21 January 2018

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Leptin promotes rapid dynamic changes in hippocampal dendritic morphology

21 January 2018

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Drug Insight: the role of leptin in human physiology and pathophysiology--emerging clinical applications

21 January 2018

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Leptin increases adult hippocampal neurogenesis in vivo and in vitro

21 January 2018

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Dysregulation of leptin signaling in Alzheimer disease: evidence for neuronal leptin resistance

21 January 2018

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Serum leptin level and cognition in the elderly: Findings from the Health ABC Study

21 January 2018

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Altered serum levels of adipokines and insulin in probable Alzheimer's disease.

21 January 2018

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Association of plasma leptin levels with incident Alzheimer disease and MRI measures of brain aging

21 January 2018

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Regulation of neuronal and glial proteins by leptin: implications for brain development

21 January 2018

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Leptin signaling in astrocytes regulates hypothalamic neuronal circuits and feeding

21 January 2018

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Neuroprotective effects of leptin in vivo and in vitro

21 January 2018

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Leptin inhibits 1-methyl-4-phenylpyridinium-induced cell death in SH-SY5Y cells

21 January 2018

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Leptin protects hippocampal CA1 neurons against ischemic injury

21 January 2018

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Reduced hippocampal insulin-degrading enzyme in late-onset Alzheimer's disease is associated with the apolipoprotein E-epsilon4 allele

21 January 2018

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Metabolic regulation of brain Abeta by neprilysin.

21 January 2018

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Plaque-associated overexpression of insulin-degrading enzyme in the cerebral cortex of aged transgenic tg2576 mice with Alzheimer pathology.

21 January 2018

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Insulin-degrading enzyme regulates extracellular levels of amyloid beta-protein by degradation

21 January 2018

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Insulin-degrading enzyme secretion from astrocytes is mediated by an autophagy-based unconventional secretory pathway in Alzheimer disease.

21 January 2018

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Age- and region-dependent alterations in Abeta-degrading enzymes: implications for Abeta-induced disorders

21 January 2018

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Neprilysin: an enzyme candidate to slow the progression of Alzheimer's disease

21 January 2018

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Are amyloid-degrading enzymes viable therapeutic targets in Alzheimer's disease?

21 January 2018

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Mechanisms of Aβ Clearance and Degradation by Glial Cells

21 January 2018

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Tau oligomers as potential targets for Alzheimer's diagnosis and novel drugs

21 January 2018

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The role of tau phosphorylation in the pathogenesis of Alzheimer's disease

21 January 2018

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Role of abnormally phosphorylated tau in the breakdown of microtubules in Alzheimer disease

21 January 2018

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Primed phosphorylation of tau at Thr231 by glycogen synthase kinase 3beta (GSK3beta) plays a critical role in regulating tau's ability to bind and stabilize microtubules

21 January 2018

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GSK-3beta down-regulates the transcription factor Nrf2 after oxidant damage: relevance to exposure of neuronal cells to oxidative stress.

21 January 2018

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Targeting p38 MAPK pathway for the treatment of Alzheimer's disease

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Modulation of GSK-3 as a Therapeutic Strategy on Tau Pathologies

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Resveratrol Ameliorates Tau Hyperphosphorylation at Ser396 Site and Oxidative Damage in Rat Hippocampal Slices Exposed to Vanadate: Implication of ERK1/2 and GSK-3β Signaling Cascades.

21 January 2018

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Curcumin Decreases Hyperphosphorylation of Tau by Down-Regulating Caveolin-1/GSK-3β in N2a/APP695swe Cells and APP/PS1 Double Transgenic Alzheimer's Disease Mice.

21 January 2018

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Capsaicin reduces Alzheimer-associated tau changes in the hippocampus of type 2 diabetes rats

21 January 2018

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The application of in silico drug-likeness predictions in pharmaceutical research

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES23010117

Pharmacokinetics and disposition of monoterpene glycosides derived from Paeonia lactiflora roots (Chishao) after intravenous dosing of antiseptic XueBiJing injection in human subjects and rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES23010117

Metabolism in rats of p-cymene derivatives: carvacrol and thymol

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES23010117

Systemic availability and pharmacokinetics of thymol in humans.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES23010117

Human breast tissue disposition and bioactivity of limonene in women with early-stage breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES23010117

Adipose tissue accumulation of d-limonene with the consumption of a lemonade preparation rich in d-limonene content.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES23010117

Comparative oral bioavailability of geniposide following oral administration of geniposide, Gardenia jasminoides Ellis fruits extracts and Gardenia herbal formulation in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES23010117

Simultaneous determination of geniposide and its metabolites genipin and genipinine in culture of Aspergillus niger by HPLC.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES23010117

Natural Therapies of the Inflammatory Bowel Disease: The Case of Rutin and its Aglycone, Quercetin.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES23010117

Effects of borneol on the pharmacokinetics of geniposide in cortex, hippocampus, hypothalamus and striatum of conscious rat by simultaneous brain microdialysis coupled with UPLC-MS.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES23010117

Essential Oils and Pure Volatile Compounds as Potential Drugs in Alzheimer's Disease Therapy: An Updated Review of the Literature.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES23010117

Enzymic studies on the animal and intestinal bacterial metabolism of geniposide

21 January 2018

1 reference

12 December 2020

Cellular phosphorylation of tau by GSK-3 beta influences tau binding to microtubules and microtubule organisation

1 reference

12 December 2020

Flavonoids as inhibitors or enhancers of the cytotoxicity of tumor necrosis factor-alpha in L-929 tumor cells

1 reference

12 December 2020

Neurons regulate extracellular levels of amyloid beta-protein via proteolysis by insulin-degrading enzyme

1 reference

12 December 2020

Mechanisms responsible for poor oral bioavailability of paeoniflorin: Role of intestinal disposition and interactions with sinomenine

1 reference

12 December 2020

New insights into the roles of metalloproteinases in neurodegeneration and neuroprotection

1 reference

12 December 2020

Inflammatory aspects of Alzheimer disease and other neurodegenerative disorders

1 reference

12 December 2020

Antioxidant principles of Tanacetum vulgare L. aerial parts.

1 reference

12 December 2020

A-glucosidase inhibitory activity of kaempferol-3-O-rutinoside

1 reference

12 December 2020

Investigation of UDP-glucuronosyltransferases (UGTs) inhibitory properties of carvacrol

1 reference

12 December 2020

Identification of metabolites of geniposide in rat urine using ultra-performance liquid chromatography combined with electrospray ionization quadrupole time-of-flight tandem mass spectrometry

1 reference

12 December 2020

Phytochemical, antioxidant and anti-α-glucosidase activity evaluations of Bergenia cordifolia

1 reference

12 December 2020

Determination of the plasma pharmacokinetic and tissue distributions of swertiamarin in rats by liquid chromatography with tandem mass spectrometry

1 reference

12 December 2020

Antioxidant and anti-α-glucosidase compounds from the rhizome of Peltiphyllum peltatum (Torr.) Engl

1 reference

12 December 2020

β-Secretase (BACE1) inhibitory property of loganin isolated from Corni fructus

1 reference

12 December 2020

Protective effect of paeoniflorin against glutamate-induced neurotoxicity in PC12 cells via Bcl-2/Bax signal pathway

1 reference

12 December 2020

Peoniflorin activates Nrf2/ARE pathway to alleviate the Abeta(1-42)-induced hippocampal neuron injury in rats

1 reference

12 December 2020

Use of a new water-soluble Zn sensor to determine Zn affinity for the amyloid-β peptide and relevant mutants

1 reference

12 December 2020

Catalpol regulates function of hypothalamic-pituitary-adrenocortical-axis in an Alzheimer's disease rat model.

1 reference

12 December 2020

Paeoniflorin attenuates Aβ25-35-induced neurotoxicity in PC12 cells by preventing mitochondrial dysfunction.

1 reference

12 December 2020

[Role of PI3K/Akt pathway in effect of paeoniflorin against Aβ25-35-induced PC12 cell injury].

1 reference

12 December 2020

Investigation into the antioxidant and antidiabetic potential of Moringa stenopetala: identification of the active principles

1 reference

12 December 2020

Hyperforin attenuates aluminum-induced Aβ production and Tau phosphorylation via regulating Akt/GSK-3β signaling pathway in PC12 cells

1 reference

12 December 2020

10.3390/MOLECULES23010117

Identifiers

DOI

1 reference

11 January 2018

0 references

1 reference

11 January 2018