Apurinic/apyrimidinic endonuclease (APE/REF-1) haploinsufficient mice display tissue-specific differences in DNA polymerase beta-dependent base excision repair. (Q47197545)

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scientific article published on 18 February 2004

Language	Label	Description	Also known as
English	Apurinic/apyrimidinic endonuclease (APE/REF-1) haploinsufficient mice display tissue-specific differences in DNA polymerase beta-dependent base excision repair.	scientific article published on 18 February 2004

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scholarly article

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23 November 2019

Apurinic/apyrimidinic endonuclease (APE/REF-1) haploinsufficient mice display tissue-specific differences in DNA polymerase beta-dependent base excision repair (English)

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23 November 2019

haploinsufficiency

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Lisiane B Meira

4

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23 November 2019

author name string

Julian J Raffoul

1

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23 November 2019

Diane C Cabelof

2

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Jun Nakamura

3

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Errol C Friedberg

5

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Ahmad R Heydari

6

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publication date

18 February 2004

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23 November 2019

Journal of Biological Chemistry

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279

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18

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18425-18433

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23 November 2019

Yeast structural gene (APN1) for the major apurinic endonuclease: homology to Escherichia coli endonuclease IV

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313983200

21 January 2018

A mouse DNA repair enzyme (APEX nuclease) having exonuclease and apurinic/apyrimidinic endonuclease activities: purification and characterization

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313983200

21 January 2018

Isolation of cDNA clones encoding a human apurini/apyrimidinic endonuclease that corects DNA repair and mutagenisis defects inE.coli xth(exonuclease III) mutants

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313983200

21 January 2018

Repair mechanisms for oxidative DNA damage

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313983200

21 January 2018

Going APE over ref-1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313983200

21 January 2018

Cysteine 64 of Ref-1 is not essential for redox regulation of AP-1 DNA binding

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313983200

21 January 2018

Infidelity of DNA synthesis associated with bypass of apurinic sites

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313983200

21 January 2018

The stalling of transcription at abasic sites is highly mutagenic

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313983200

21 January 2018

Base excision repair intermediates as topoisomerase II poisons

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313983200

21 January 2018

DNA damage and repair

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313983200

21 January 2018

Mechanisms of human DNA repair: an update

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313983200

21 January 2018

Mammalian abasic site base excision repair. Identification of the reaction sequence and rate-determining steps

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313983200

21 January 2018

Drosophila S3 ribosomal protein accelerates repair of 8-oxoguanine performed by human and mouse cell extracts

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313983200

21 January 2018

Dynamics and diversions in base excision DNA repair of oxidized abasic lesions

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313983200

21 January 2018

Completion of base excision repair by mammalian DNA ligases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313983200

21 January 2018

XRCC1 coordinates the initial and late stages of DNA abasic site repair through protein-protein interactions

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313983200

21 January 2018

Interaction of human apurinic endonuclease and DNA polymerase beta in the base excision repair pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313983200

21 January 2018

DNA polymerase beta is the major dRP lyase involved in repair of oxidative base lesions in DNA by mammalian cell extracts

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313983200

21 January 2018

Stimulation of human 8-oxoguanine-DNA glycosylase by AP-endonuclease: potential coordination of the initial steps in base excision repair

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313983200

21 January 2018

Mechanism of stimulation of the DNA glycosylase activity of hOGG1 by the major human AP endonuclease: bypass of the AP lyase activity step

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313983200

21 January 2018

Role of XRCC1 in the coordination and stimulation of oxidative DNA damage repair initiated by the DNA glycosylase hOGG1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313983200

21 January 2018

Substrate specificity of human endonuclease III (hNTH1). Effect of human APE1 on hNTH1 activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313983200

21 January 2018

A quantitative model of human DNA base excision repair. I. Mechanistic insights

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313983200

21 January 2018

A murine AP-endonuclease gene-targeted deficiency with post-implantation embryonic progression and ionizing radiation sensitivity.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313983200

21 January 2018

The redox/DNA repair protein, Ref-1, is essential for early embryonic development in mice.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313983200

21 January 2018

p53 regulation of DNA excision repair pathways

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313983200

21 January 2018

Functional characterization of Ape1 variants identified in the human population

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313983200

21 January 2018

Polymorphisms in DNA repair and environmental interactions

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313983200

21 January 2018

Challenges and complexities in estimating both the functional impact and the disease risk associated with the extensive genetic variation in human DNA repair genes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313983200

21 January 2018

Incision activity of human apurinic endonuclease (Ape) at abasic site analogs in DNA

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313983200

21 January 2018

Reduction of oxidation during the preparation of DNA and analysis of 8-hydroxy-2'-deoxyguanosine.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313983200

21 January 2018

Quantification of 3'OH DNA breaks by random oligonucleotide-primed synthesis (ROPS) assay

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313983200

21 January 2018

A role for the human DNA repair enzyme HAP1 in cellular protection against DNA damaging agents and hypoxic stress

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313983200

21 January 2018

Induction of DNA polymerase beta-dependent base excision repair in response to oxidative stress in vivo

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313983200

21 January 2018

Attenuation of DNA polymerase beta-dependent base excision repair and increased DMS-induced mutagenicity in aged mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313983200

21 January 2018

Mixed spermatogenic germ cell nuclear extracts exhibit high base excision repair activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313983200

21 January 2018

Caloric restriction promotes genomic stability by induction of base excision repair and reversal of its age-related decline

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313983200

21 January 2018

A role for p53 in base excision repair.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313983200

21 January 2018

Biochemical entities involved in reactive oxygen species generation by human spermatozoa.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313983200

21 January 2018

Comparative analysis of the ability of precursor germ cells and epididymal spermatozoa to generate reactive oxygen metabolites.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313983200

21 January 2018

Oxidative stress associated DNA damage in testis of mice: induction of abnormal sperms and effects on fertility

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313983200

21 January 2018

Quantitative analysis of gene-specific DNA damage in human spermatozoa.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313983200

21 January 2018

Highly efficient base excision repair (BER) in human and rat male germ cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313983200

21 January 2018

Mammalian DNA base excision repair proteins: their interactions and role in repair of oxidative DNA damage

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313983200

21 January 2018

p53, the cellular gatekeeper for growth and division

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313983200

21 January 2018

Ref-1 regulates the transactivation and pro-apoptotic functions of p53 in vivo.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313983200

21 January 2018

Identification of redox/repair protein Ref-1 as a potent activator of p53

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313983200

21 January 2018

AP endonuclease 1 has no biologically significant 3(')-->5(')-exonuclease activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313983200

21 January 2018

Passing the baton in base excision repair

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313983200

21 January 2018

Database of mouse strains carrying targeted mutations in genes affecting biological responses to DNA damage. Version 5

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313983200

21 January 2018

Carboplatin treatment induces dose-dependent increases in the frequency of micronuclei in Ehrlich ascites tumor cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313983200

21 January 2018

Lipid Peroxidation and the Reactions of Superoxide and Hydrogen Peroxide in Mouse Spermatozoa

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313983200

21 January 2018

Genetic interaction between HAP1/REF-1 and p53

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313983200

21 January 2018

Identifiers

10.1074/JBC.M313983200

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14973123%20AND%20SRC:MED&resulttype=core&format=json

23 November 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14973123%20AND%20SRC:MED&resulttype=core&format=json

23 November 2019

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