Pre-clinical antigenicity studies of an innovative multivalent vaccine for human visceral leishmaniasis (Q47137387)

9 January 2018

title

Pre-clinical antigenicity studies of an innovative multivalent vaccine for human visceral leishmaniasis (English)

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9 January 2018

main subject

visceral leishmaniasis

1 reference

Anabela Cordeiro-da-Silva

inferred from title

author

16

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9 January 2018

Pedro Cecílio

Pedro Cecílio

1

0 references

Begoña Pérez-Cabezas

Begoña Pérez-Cabezas

2

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Javier Moreno

Javier Moreno

4

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Epifanio Fichera

Epifanio Fichera

7

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Fabiano Oliveira

Fabiano Oliveira

11

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Steven G Reed

8

Steven G Reed

1 reference

9 January 2018

José María Requena

José M Requena

6

0 references

Rhea N Coler

9

Rhea N Coler

1 reference

9 January 2018

Luigi Gradoni

13

Luigi Gradoni

1 reference

9 January 2018

Jesus G Valenzuela

12

Jesus G Valenzuela

1 reference

9 January 2018

author name string

Laura Fernández

3

1 reference

9 January 2018

Eugenia Carrillo

5

1 reference

9 January 2018

José M Requena

6

1 reference

9 January 2018

Shaden Kamhawi

10

1 reference

9 January 2018

Reinhard Glueck

14

1 reference

9 January 2018

Gaurav Gupta

15

1 reference

9 January 2018

language of work or name

English

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publication date

27 November 2017

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9 January 2018

PLoS Neglected Tropical Diseases

published in

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9 January 2018

volume

11

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9 January 2018

page(s)

e0005951

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9 January 2018

issue

11

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9 January 2018

Creative Commons CC0 License

copyright license

start time

27 November 2017

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted, dedicated to the public domain by copyright holder

0 references

cites work

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Intradermal Immunization of Leishmania donovani Centrin Knock-Out Parasites in Combination with Salivary Protein LJM19 from Sand Fly Vector Induces a Durable Protective Immune Response in Hamsters.

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23 May 2018

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Immunomodulation in human dendritic cells leads to induction of interferon-gamma production by Leishmania donovani derived KMP-11 antigen via activation of NF-κB in Indian kala-azar patients

23 May 2018

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23 May 2018

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Heterologous priming-boosting with DNA and vaccinia virus expressing kinetoplastid membrane protein-11 induces potent cellular immune response and confers protection against infection with antimony resistant and sensitive strains of Leishmania (Leis

23 May 2018

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Glucopyranosyl Lipid Adjuvant (GLA), a Synthetic TLR4 agonist, promotes potent systemic and mucosal responses to intranasal immunization with HIVgp140.

23 May 2018

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23 May 2018

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GLA-SE, a synthetic toll-like receptor 4 agonist, enhances T-cell responses to influenza vaccine in older adults

23 May 2018

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23 May 2018

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Lutzomyia longipalpis saliva or salivary protein LJM19 protects against Leishmania braziliensis and the saliva of its vector, Lutzomyia intermedia

23 May 2018

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23 May 2018

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Interleukin-10 production by Th1 cells requires interleukin-12-induced STAT4 transcription factor and ERK MAP kinase activation by high antigen dose

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23 May 2018

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Immunity to a salivary protein of a sand fly vector protects against the fatal outcome of visceral leishmaniasis in a hamster model.

23 May 2018

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Immunity to distinct sand fly salivary proteins primes the anti-Leishmania immune response towards protection or exacerbation of disease

23 May 2018

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Protective immunization against visceral leishmaniasis using Leishmania sterol 24-c-methyltransferase formulated in adjuvant

23 May 2018

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Antigen targeting to dendritic cells elicits long-lived T cell help for antibody responses

23 May 2018

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23 May 2018

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Kinetoplastid membrane protein-11 DNA vaccination induces complete protection against both pentavalent antimonial-sensitive and -resistant strains of Leishmania donovani that correlates with inducible nitric oxide synthase activity and IL-4 generati

23 May 2018

1 reference

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Recombinant DNA-derived leishmania proteins: from the laboratory to the field

23 May 2018

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Cross-protective efficacy of a prophylactic Leishmania donovani DNA vaccine against visceral and cutaneous murine leishmaniasis

23 May 2018

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Leishmaniasis: new approaches to disease control

23 May 2018

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New technology platforms in the development of vaccines for the future

23 May 2018

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Development of a natural model of cutaneous leishmaniasis: powerful effects of vector saliva and saliva preexposure on the long-term outcome of Leishmania major infection in the mouse ear dermis

23 May 2018

1 reference

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TLR-mediated distinct IFN-γ/IL-10 pattern induces protective immunity against murine visceral leishmaniasis.

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5720812

KMP-11 DNA immunization significantly protects against L. donovani infection but requires exogenous IL-12 as an adjuvant for comparable protection against L. major.

15 August 2018

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Cysteine proteinase type III is protective against Leishmania infantum infection in BALB/c mice and highly antigenic in visceral leishmaniasis individuals

15 August 2018

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Failure of a multi-subunit recombinant leishmanial vaccine (MML) to protect dogs from Leishmania infantum infection and to prevent disease progression in infected animals.

15 August 2018

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Low antigen dose favours selection of somatic mutants with hallmarks of antibody affinity maturation.

15 August 2018

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Effect of LACK and KMP11 on IFN-gamma Production by Peripheral Blood Mononuclear Cells from Cutaneous and Mucosal Leishmaniasis Patients

15 August 2018

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Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PNTD.0005951

Protection Against Cutaneous Leishmaniasis Resulting from Bites of Uninfected Sand Flies

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29176865

12 December 2020

inferred from PubMed ID database lookup

Attenuated Toxoplasma gondii ts-4 mutants engineered to express the Leishmania antigen KMP-11 elicit a specific immune response in BALB/c mice

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29176865

12 December 2020

inferred from PubMed ID database lookup

Virosome-mediated delivery of protein antigens to dendritic cells

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PubMed

https://pubmed.ncbi.nlm.nih.gov/29176865

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1371/JOURNAL.PNTD.0005951

1 reference

9 January 2018

PMCID

5720812

1 reference

9 January 2018

PubMed ID

29176865

1 reference

9 January 2018