Presenilin1 regulates histamine neuron development and behavior in zebrafish, danio rerio (Q47073527)

5 January 2018

http://europepmc.org/abstract/MED/23345232

title

Presenilin1 regulates histamine neuron development and behavior in zebrafish, danio rerio (English)

1 reference

5 January 2018

http://europepmc.org/abstract/MED/23345232

0 references

1 reference

GOA release 2020-03-11

author

Pertti Panula

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6618731&resulttype=core&format=json

15 May 2020

author name string

Maria Sundvik

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6618731&resulttype=core&format=json

15 May 2020

Yu-Chia Chen

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6618731&resulttype=core&format=json

15 May 2020

language of work or name

English

0 references

publication date

1 January 2013

1 reference

5 January 2018

http://europepmc.org/abstract/MED/23345232

published in

Journal of Neuroscience

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6618731&resulttype=core&format=json

15 May 2020

volume

33

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6618731&resulttype=core&format=json

15 May 2020

issue

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6618731&resulttype=core&format=json

15 May 2020

page(s)

1589-1597

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6618731&resulttype=core&format=json

A presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain

15 May 2020

cites work

1 reference

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Notch signaling: cell fate control and signal integration in development

1 reference

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Zebrafish (Danio rerio) presenilin promotes aberrant amyloid beta-peptide production and requires a critical aspartate residue for its function in amyloidogenesis

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Effect of PS1 deficiency and an APP gamma-secretase inhibitor on Notch1 signaling in primary mammalian neurons

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Loss of presenilin 1 is associated with enhanced beta-catenin signaling and skin tumorigenesis

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Comparative anatomy of the histaminergic and other aminergic systems in zebrafish (Danio rerio).

1 reference

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The elongation factors Pandora/Spt6 and Foggy/Spt5 promote transcription in the zebrafish embryo

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Overexpression of wild type but not an FAD mutant presenilin-1 promotes neurogenesis in the hippocampus of adult mice.

1 reference

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Presenilin couples the paired phosphorylation of beta-catenin independent of axin: implications for beta-catenin activation in tumorigenesis

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The novel presenilin-1-associated protein is a proapoptotic mitochondrial protein

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The role of histamine and the tuberomamillary nucleus in the nervous system

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γ-Secretase is a membrane protein complex comprised of presenilin, nicastrin, aph-1, and pen-2

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Modulation of the histaminergic system and behaviour by alpha-fluoromethylhistidine in zebrafish

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Developmental control of Presenilin1 expression, endoproteolysis, and interaction in zebrafish embryos.

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Dysregulated IP3 signaling in cortical neurons of knock-in mice expressing an Alzheimer's-linked mutation in presenilin1 results in exaggerated Ca2+ signals and altered membrane excitability.

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Nicastrin, presenilin, APH-1, and PEN-2 form active gamma-secretase complexes in mitochondria

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Twenty years of the Alzheimer's disease amyloid hypothesis: a genetic perspective

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Cadherins mediate both the association between PS1 and beta-catenin and the effects of PS1 on beta-catenin stability

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Identification of zebrafish histamine H1, H2 and H3 receptors and effects of histaminergic ligands on behavior

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GSK189254, a novel H3 receptor antagonist that binds to histamine H3 receptors in Alzheimer's disease brain and improves cognitive performance in preclinical models

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Interference with splicing of Presenilin transcripts has potent dominant negative effects on Presenilin activity

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Modulatory neurotransmitter systems and behavior: towards zebrafish models of neurodegenerative diseases

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Histamine induces neural stem cell proliferation and neuronal differentiation by activation of distinct histamine receptors.

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Histamine in the nervous system

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Identification of proSAAS homologs in lower vertebrates: conservation of hydrophobic helices and convertase-inhibiting sequences

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Interaction with Notch determines endocytosis of specific Delta ligands in zebrafish neural tissue

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Impaired cell proliferation in the subventricular zone in an Alzheimer's disease model.

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Independent and cooperative action of Psen2 with Psen1 in zebrafish embryos.

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DeltaA mRNA and protein distribution in the zebrafish nervous system

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Emerging roles of Wnts in the adult nervous system

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In vivo manifestation of Notch related phenotypes in zebrafish treated with Alzheimer's amyloid reducing gamma-secretase inhibitors

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The comparative neuroanatomy and neurochemistry of zebrafish CNS systems of relevance to human neuropsychiatric diseases

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Presenilin 1 mutants impair the self-renewal and differentiation of adult murine subventricular zone-neuronal progenitors via cell-autonomous mechanisms involving notch signaling

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Novel research horizons for presenilins and γ-secretases in cell biology and disease

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Presenilin mouse and zebrafish models for dementia: focus on neurogenesis

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DeltaA/DeltaD regulate multiple and temporally distinct phases of notch signaling during dopaminergic neurogenesis in zebrafish.

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Not(ch) just development: Notch signalling in the adult brain

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The histaminergic system regulates wakefulness and orexin/hypocretin neuron development via histamine receptor H1 in zebrafish

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Histamine pharmacology and new CNS drug targets.

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Activity-dependent neurotransmitter respecification

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Notch Signaling Controls Generation of Motor Neurons in the Lesioned Spinal Cord of Adult Zebrafish

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Organization of the histaminergic system in adult zebrafish (Danio rerio) brain: neuron number, location, and cotransmitters

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Facilitation of lin-12-mediated signalling by sel-12, a Caenorhabditis elegans S182 Alzheimer's disease gene

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Histamine-immunoreactive neurons in the brain of the teleost Gasterosteus aculeatus L. Correlation with hypothalamic tyrosine hydroxylase- and serotonin-immunoreactive neurons

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Alzheimer-associated presenilins 1 and 2: neuronal expression in brain and localization to intracellular membranes in mammalian cells.

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Familial Alzheimer's disease-linked presenilin 1 variants elevate Abeta1-42/1-40 ratio in vitro and in vivo

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Alzheimer's PS-1 mutation perturbs calcium homeostasis and sensitizes PC12 cells to death induced by amyloid beta-peptide.

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Skeletal and CNS defects in Presenilin-1-deficient mice

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Neuronal histamine deficit in Alzheimer's disease.

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Development of the histaminergic neurons and expression of histidine decarboxylase mRNA in the zebrafish brain in the absence of all peripheral histaminergic systems.

1 reference

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10.1523/JNEUROSCI.1802-12.2013

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6618731&resulttype=core&format=json

15 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6618731&resulttype=core&format=json

15 May 2020

1 reference