Melatonin attenuates D-galactose-induced memory impairment, neuroinflammation and neurodegeneration via RAGE/NF-K B/JNK signaling pathway in aging mouse model (Q46813751)

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English	Melatonin attenuates D-galactose-induced memory impairment, neuroinflammation and neurodegeneration via RAGE/NF-K B/JNK signaling pathway in aging mouse model	scientific article

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scholarly article

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/25401971

Melatonin attenuates D-galactose-induced memory impairment, neuroinflammation and neurodegeneration via RAGE/NF-K B/JNK signaling pathway in aging mouse model (English)

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/25401971

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author name string

Tahir Ali

1

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/25401971

Haroon Badshah

2

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Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/25401971

Tae Hyun Kim

3

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/25401971

Myeong Ok Kim

4

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Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/25401971

publication date

9 December 2014

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Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/25401971

Journal of Pineal Research

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Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/25401971

58

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Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/25401971

71-85

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Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/25401971

1

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Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/25401971

Trajectories of brain aging in middle-aged and older adults: regional and individual differences

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Mitochondrial dysfunction in brain aging: role of oxidative stress and cardiolipin

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Behavioural study of the D-galactose induced aging model in C57BL/6J mice

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Ursolic acid ameliorates cognition deficits and attenuates oxidative damage in the brain of senescent mice induced by D-galactose.

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Purple sweet potato color alleviates D-galactose-induced brain aging in old mice by promoting survival of neurons via PI3K pathway and inhibiting cytochrome C-mediated apoptosis.

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Quercetin reverses D-galactose induced neurotoxicity in mouse brain.

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Advanced glycation endproduct-induced aging of the retinal pigment epithelium and choroid: a comprehensive transcriptional response

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Impairments of astrocytes are involved in the d-galactose-induced brain aging.

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Purple sweet potato color repairs d-galactose-induced spatial learning and memory impairment by regulating the expression of synaptic proteins.

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Ursolic acid attenuates D-galactose-induced inflammatory response in mouse prefrontal cortex through inhibiting AGEs/RAGE/NF-κB pathway activation.

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Regulation of antioxidant enzymes: a significant role for melatonin

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On the free radical scavenging activities of melatonin's metabolites, AFMK and AMK.

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Melatonin: a well-documented antioxidant with conditional pro-oxidant actions

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Visualization of melatonin's multiple mitochondrial levels of protection against mitochondrial Ca(2+)-mediated permeability transition and beyond in rat brain astrocytes

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The inhibition of apoptosis by melatonin in VSC4.1 motoneurons exposed to oxidative stress, glutamate excitotoxicity, or TNF-alpha toxicity involves membrane melatonin receptors

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Involvement of autophagy in melatonin-induced cytotoxicity in glioma-initiating cells.

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Protective effects of melatonin in reducing oxidative stress and in preserving the fluidity of biological membranes: a review

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Melatonin, cardiolipin and mitochondrial bioenergetics in health and disease

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Role of melatonin and its receptors in the vertebrate retina

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The pineal gland and melatonin in relation to aging: a summary of the theories and of the data

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Alzheimer's disease: pathological mechanisms and the beneficial role of melatonin

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Long-term oral administration of melatonin improves spatial learning and memory and protects against cholinergic degeneration in middle-aged Ts65Dn mice, a model of Down syndrome

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Novel osmotin attenuates glutamate-induced synaptic dysfunction and neurodegeneration via the JNK/PI3K/Akt pathway in postnatal rat brain

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Protection of the developing brain with anthocyanins against ethanol-induced oxidative stress and neurodegeneration

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Expression of 8-oxoguanine DNA glycosylase is reduced and associated with neurofibrillary tangles in Alzheimer's disease brain.

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Oxidative DNA damage in mild cognitive impairment and late-stage Alzheimer's disease

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The effect of ageing on neurogenesis and oxidative stress in the APP(swe)/PS1(deltaE9) mouse model of Alzheimer's disease.

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Novel anti-inflammatory therapy for Parkinson's disease.

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Requirement of JNK for stress-induced activation of the cytochrome c-mediated death pathway

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Role of JNK activation in apoptosis: a double-edged sword

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Fructo-oligosaccharide attenuates the production of pro-inflammatory cytokines and the activation of JNK/Jun pathway in the lungs of D-galactose-treated Balb/cJ mice

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JNK2 translocates to the mitochondria and mediates cytochrome c release in PC12 cells in response to 6-hydroxydopamine

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PARP-1 cleavage fragments: signatures of cell-death proteases in neurodegeneration

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Fluoro-Jade B: a high affinity fluorescent marker for the localization of neuronal degeneration

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D-galactose injured neurogenesis in the hippocampus of adult mice.

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Advanced glycation endproducts and their receptor RAGE in Alzheimer's disease.

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Understanding RAGE, the receptor for advanced glycation end products

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Chronic systemic D-galactose exposure induces memory loss, neurodegeneration, and oxidative damage in mice: protective effects of R-alpha-lipoic acid

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Synaptic accumulation of PSD-95 and synaptic function regulated by phosphorylation of serine-295 of PSD-95.

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Effect of inhibiting melatonin biosynthesis on spatial memory retention and tau phosphorylation in rat.

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Signaling to NF-kappaB

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Sustained, neuron-specific IKK/NF-κB activation generates a selective neuroinflammatory response promoting local neurodegeneration with aging

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21 January 2018

Identifiers

10.1111/JPI.12194

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/25401971

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/25401971

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