Advanced glycation endproduct-induced aging of the retinal pigment epithelium and choroid: a comprehensive transcriptional response (Q33911788)

30 July 2017

Advanced glycation endproduct-induced aging of the retinal pigment epithelium and choroid: a comprehensive transcriptional response (English)

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30 July 2017

Jane Tian

1

1 reference

30 July 2017

Kazuki Ishibashi

2

1 reference

30 July 2017

Kazuko Ishibashi

3

1 reference

30 July 2017

Karen Reiser

4

1 reference

30 July 2017

Rhonda Grebe

5

1 reference

30 July 2017

Shyam Biswal

6

1 reference

30 July 2017

Peter Gehlbach

7

1 reference

30 July 2017

James T Handa

8

1 reference

30 July 2017

language of work or name

English

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publication date

4 August 2005

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Proceedings of the National Academy of Sciences of the United States of America

30 July 2017

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30 July 2017

102

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30 July 2017

33

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30 July 2017

11846-11851

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Retina expresses microsomal triglyceride transfer protein: implications for age-related maculopathy.

30 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1182551

Proteoglycans in atherosclerosis and restenosis: key roles for versican

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1182551

Gene expression in aging kidney and pituitary.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1182551

Genetic risk factors for stroke and carotid atherosclerosis: insights into pathophysiology from candidate gene approaches

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1182551

Extracellular matrix components in atherosclerotic arteries of Apo E/LDL receptor deficient mice: an immunohistochemical study

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1182551

Human alphaA- and alphaB-crystallins bind to Bax and Bcl-X(S) to sequester their translocation during staurosporine-induced apoptosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1182551

Regulation of stearoyl-CoA desaturases and role in metabolism

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1182551

Proteins modified by malondialdehyde, 4-hydroxynonenal, or advanced glycation end products in lipofuscin of human retinal pigment epithelium

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1182551

Apolipoprotein B in cholesterol-containing drusen and basal deposits of human eyes with age-related maculopathy

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1182551

Increased lipolysis in transgenic animals overexpressing the epithelial fatty acid binding protein in adipose cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1182551

Transcriptional profiles associated with aging and middle age-onset caloric restriction in mouse hearts

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1182551

Retinal pigment epithelium is protected against apoptosis by alphaB-crystallin.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1182551

Angiopoietin-like protein 4 is a potent hyperlipidemia-inducing factor in mice and inhibitor of lipoprotein lipase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1182551

Drusen proteome analysis: an approach to the etiology of age-related macular degeneration.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1182551

Proapoptotic and antitumor activities of adenovirus-mediated p202 gene transfer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1182551

Aberrant accumulation of EFEMP1 underlies drusen formation in Malattia Leventinese and age-related macular degeneration

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1182551

Clinical manifestations of atherosclerosis in an elderly population are related to plasma neopterin, NGAL and endothelin-1, but not to Chlamydia pneumoniae serology.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1182551

Production of the long pentraxin PTX3 in advanced atherosclerotic plaques

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1182551

CST3 genotype associated with exudative age related macular degeneration

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1182551

Tumor necrosis factor-alpha induces the expression of DR6, a member of the TNF receptor family, through activation of NF-kappaB

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1182551

An integrated hypothesis that considers drusen as biomarkers of immune-mediated processes at the RPE-Bruch's membrane interface in aging and age-related macular degeneration

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1182551

Induction of an aging mRNA retinal pigment epithelial cell phenotype by matrix-containing advanced glycation end products in vitro

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1182551

Induction of apoptosis by a secreted lipocalin that is transcriptionally regulated by IL-3 deprivation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1182551

Lack of macrophage fatty-acid-binding protein aP2 protects mice deficient in apolipoprotein E against atherosclerosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1182551

Complement components as uremic toxins and their potential role as mediators of microinflammation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1182551

Accumulation of cholesterol with age in human Bruch's membrane.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1182551

The biosynthesis of hepatic cholesterol esters and triglycerides is impaired in mice with a disruption of the gene for stearoyl-CoA desaturase 1

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1182551

Interleukin-6 exacerbates early atherosclerosis in mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1182551

Gene expression profile of aging and its retardation by caloric restriction

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1182551

Development of a polyclonal antibody with broad epitope specificity for advanced glycation endproducts and localization of these epitopes in Bruch's membrane of the aging eye.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1182551

Functional roles of S100 proteins, calcium-binding proteins of the EF-hand type

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1182551

A single EFEMP1 mutation associated with both Malattia Leventinese and Doyne honeycomb retinal dystrophy

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1182551

Increase in the advanced glycation end product pentosidine in Bruch's membrane with age.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1182551

The hydrophobic pocket of 24p3 protein from mouse uterine luminal fluid: fatty acid and retinol binding activity and predicted structural similarity to lipocalins.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1182551

Immunohistochemical light and electron microscopy of basal laminar deposit

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1182551

The response-to-retention hypothesis of early atherogenesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1182551

Advanced protein glycosylation in diabetes and aging

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1182551

Ageing and degeneration in the macular region: a clinico-pathological study

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1182551

5 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0504759102

Ultrastructural aging of the RPE-Bruch's membrane-choriocapillaris complex in the D-galactose-treated mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0504759102

The role of aging, high fat diet and blue light exposure in an experimental mouse model for basal laminar deposit formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0504759102

Impact of aging and age-related maculopathy on activation of the a-wave of the rod-mediated electroretinogram

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0504759102

Carboxyethylpyrrole protein adducts and autoantibodies, biomarkers for age-related macular degeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0504759102

Role of ATP on the interaction of alpha-crystallin with its substrates and its implications for the molecular chaperone function

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0504759102

Vascular inflammation is negatively autoregulated by interaction between CCAAT/enhancer-binding protein-delta and peroxisome proliferator-activated receptor-gamma

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0504759102

Association between C-reactive protein and age-related macular degeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0504759102

The role of apoptosis in age-related macular degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0504759102

Drusen are Cold Spots for Proteolysis: Expression of Matrix Metalloproteinases and Their Tissue Inhibitor Proteins in Age-related Macular Degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0504759102

Depletion of a fatty acid-binding protein impairs neurite outgrowth in PC12 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0504759102

Heart fatty acid uptake is decreased in heart fatty acid-binding protein gene-ablated mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0504759102

Apolipoprotein B production reduces lipotoxic cardiomyopathy: studies in heart-specific lipoprotein lipase transgenic mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0504759102

Detection of specific extracellular matrix molecules in drusen, Bruch's membrane, and ciliary body

21 January 2018

1 reference

12 December 2020

1 reference

12 December 2020

Oxidation of low density lipoproteins greatly enhances their association with lipoprotein lipase anchored to endothelial cell matrix

1 reference

12 December 2020

A heterocomplex formed by the calcium-binding proteins MRP8 (S100A8) and MRP14 (S100A9) binds unsaturated fatty acids with high affinity

1 reference

12 December 2020

Leukocyte activation in atherosclerosis: correlation with risk factors

1 reference

12 December 2020

Associations of elevated interleukin-6 and C-reactive protein levels with mortality in the elderly

1 reference

12 December 2020

Lipoprotein lipase enhances the binding of native and oxidized low density lipoproteins to versican and biglycan synthesized by cultured arterial smooth muscle cells

1 reference

12 December 2020

Gene-expression profile of the ageing brain in mice

1 reference

12 December 2020

Ultrastructural changes in Bruch's membrane of apolipoprotein E-deficient mice

1 reference

12 December 2020

Oxidized LDL induces the expression of ALBP/aP2 mRNA and protein in human THP-1 macrophages

1 reference

12 December 2020

1 reference

12 December 2020

Enhanced thrombosis in atherosclerosis-prone mice is associated with increased arterial expression of plasminogen activator inhibitor-1

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0504759102

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30 July 2017

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30 July 2017

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