Nol12 is a multifunctional RNA binding protein at the nexus of RNA and DNA metabolism. (Q46606403)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29069457%20AND%20SRC:MED&resulttype=core&format=json

8 April 2020

title

Nol12 is a multifunctional RNA binding protein at the nexus of RNA and DNA metabolism (English)

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8 April 2020

10

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8 April 2020

Daniel D Scott

1

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8 April 2020

Eric Van Nostrand

6

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8 April 2020

Srivathsan Adivarahan

7

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8 April 2020

author name string

Christian Trahan

2

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8 April 2020

Pierre J Zindy

3

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8 April 2020

Lisbeth C Aguilar

4

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8 April 2020

Marc Y Delubac

5

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8 April 2020

Karen E Wei

8

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8 April 2020

Gene W Yeo

9

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8 April 2020

Marlene Oeffinger

11

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8 April 2020

language of work or name

English

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publication date

1 December 2017

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8 April 2020

number of pages

20

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inferred from page(s)

published in

Nucleic Acids Research

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8 April 2020

volume

45

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8 April 2020

page(s)

12509-12528

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8 April 2020

issue

21

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Creative Commons Attribution-NonCommercial 4.0 International

8 April 2020

copyright license

start time

23 October 2017

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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Double-strand break repair deficiency in NONO knockout murine embryonic fibroblasts and compensation by spontaneous upregulation of the PSPC1 paralog

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Essential Function of Dicer in Resolving DNA Damage in the Rapidly Dividing Cells of the Developing and Malignant Cerebellum.

21 January 2018

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Disruption of the nucleolus mediates stabilization of p53 in response to DNA damage and other stresses

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21 January 2018

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Perturbation of 60 S ribosomal biogenesis results in ribosomal protein L5- and L11-dependent p53 activation

21 January 2018

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Mutual protection of ribosomal proteins L5 and L11 from degradation is essential for p53 activation upon ribosomal biogenesis stress

21 January 2018

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The 5S RNP couples p53 homeostasis to ribosome biogenesis and nucleolar stress

21 January 2018

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Suprainduction of p53 by disruption of 40S and 60S ribosome biogenesis leads to the activation of a novel G2/M checkpoint.

21 January 2018

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The nucleolar protein Viriato/Nol12 is required for the growth and differentiation progression activities of the Dpp pathway during Drosophila eye development.

21 January 2018

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The Drosophila Nol12 homologue viriato is a dMyc target that regulates nucleolar architecture and is required for dMyc-stimulated cell growth.

21 January 2018

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Nucleolar protein Nop25 is involved in nucleolar architecture.

21 January 2018

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Both endonucleolytic and exonucleolytic cleavage mediate ITS1 removal during human ribosomal RNA processing

21 January 2018

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Analysis of protein complexes using mass spectrometry

21 January 2018

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Single-Step Affinity Purification (ssAP) and Mass Spectrometry of Macromolecular Complexes in the Yeast S. cerevisiae.

21 January 2018

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ProHits: integrated software for mass spectrometry-based interaction proteomics

21 January 2018

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A guided tour of the Trans-Proteomic Pipeline

21 January 2018

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Separation of long RNA by agarose-formaldehyde gel electrophoresis.

21 January 2018

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Single-molecule resolution fluorescent in situ hybridization (smFISH) in the yeast S. cerevisiae

21 January 2018

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Comprehensive analysis of diverse ribonucleoprotein complexes.

21 January 2018

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The Clothes Make the mRNA: Past and Present Trends in mRNP Fashion

21 January 2018

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Birth of a nucleolus: the evolution of nucleolar compartments

21 January 2018

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Proteomics. Tissue-based map of the human proteome

21 January 2018

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Structure of the heterodimer of human NONO and paraspeckle protein component 1 and analysis of its role in subnuclear body formation

21 January 2018

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The structure of human SFPQ reveals a coiled-coil mediated polymer essential for functional aggregation in gene regulation

21 January 2018

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NEAT1 long noncoding RNA regulates transcription via protein sequestration within subnuclear bodies

21 January 2018

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Highly ordered spatial organization of the structural long noncoding NEAT1 RNAs within paraspeckle nuclear bodies

21 January 2018

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How phosphorylation controls p53.

21 January 2018

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PAK1IP1, a ribosomal stress-induced nucleolar protein, regulates cell proliferation via the p53-MDM2 loop.

21 January 2018

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Requirement for p53 and p21 to sustain G2 arrest after DNA damage

21 January 2018

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Functional interplay between ATM/ATR-mediated DNA damage response and DNA repair pathways in oxidative stress.

21 January 2018

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MEK-ERK-mediated phosphorylation of Mdm2 at Ser-166 in hepatocytes. Mdm2 is activated in response to inhibited Akt signaling

21 January 2018

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DNA damage sensing by the ATM and ATR kinases.

21 January 2018

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The DNA-dependent protein kinase: A multifunctional protein kinase with roles in DNA double strand break repair and mitosis

21 January 2018

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Identification and characterization of a novel and specific inhibitor of the ataxia-telangiectasia mutated kinase ATM

21 January 2018

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Identification of a highly potent and selective DNA-dependent protein kinase (DNA-PK) inhibitor (NU7441) by screening of chromenone libraries

21 January 2018

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Targeting ATR in vivo using the novel inhibitor VE-822 results in selective sensitization of pancreatic tumors to radiation.

21 January 2018

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Identification of a Bis-guanylhydrazone [4,4'-Diacetyldiphenylurea-bis(guanylhydrazone); NSC 109555] as a novel chemotype for inhibition of Chk2 kinase.

21 January 2018

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CHIR-124, a novel potent inhibitor of Chk1, potentiates the cytotoxicity of topoisomerase I poisons in vitro and in vivo

21 January 2018

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Selective inhibition of the DNA-dependent protein kinase (DNA-PK) by the radiosensitizing agent caffeine

21 January 2018

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Involvement of Matrin 3 and SFPQ/NONO in the DNA damage response

21 January 2018

1 reference

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BRCT domain-containing protein TopBP1 functions in DNA replication and damage response

21 January 2018

1 reference

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p53 binding protein 1 (53BP1) is an early participant in the cellular response to DNA double-strand breaks

21 January 2018

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Quinolone action against human topoisomerase IIalpha: stimulation of enzyme-mediated double-stranded DNA cleavage

21 January 2018

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Numerical analysis of etoposide induced DNA breaks

21 January 2018

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Topoisomerase IIalpha-dependent induction of a persistent DNA damage response in response to transient etoposide exposure.

21 January 2018

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Hydrogen peroxide induces DNA single- and double-strand breaks in thyroid cells and is therefore a potential mutagen for this organ

21 January 2018

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Differential regulation of the proapoptotic multidomain protein Bak by p53 and p73 at the promoter level

21 January 2018

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rad-dependent response of the chk1-encoded protein kinase at the DNA damage checkpoint.

21 January 2018

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R-loop-mediated genomic instability is caused by impairment of replication fork progression

21 January 2018

1 reference

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Human DHX9 helicase preferentially unwinds RNA-containing displacement loops (R-loops) and G-quadruplexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKX963

SIRT7 and the DEAD-box helicase DDX21 cooperate to resolve genomic R loops and safeguard genome stability.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKX963

Human DDX21 binds and unwinds RNA guanine quadruplexes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKX963

An ATR-dependent function for the Ddx19 RNA helicase in nuclear R-loop metabolism.

21 January 2018

1 reference

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DEAD Box 1 Facilitates Removal of RNA and Homologous Recombination at DNA Double-Strand Breaks.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKX963

The RNA Response to DNA Damage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKX963

RNA Binding Proteins and Genome Integrity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKX963

53BP1 nuclear bodies form around DNA lesions generated by mitotic transmission of chromosomes under replication stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKX963

TopBP1 functions with 53BP1 in the G1 DNA damage checkpoint

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKX963

Human nucleolar protein Nop52 (RRP1/NNP-1) is involved in site 2 cleavage in internal transcribed spacer 1 of pre-rRNAs at early stages of ribosome biogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKX963

The human nucleolar protein FTSJ3 associates with NIP7 and functions in pre-rRNA processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKX963

Targeted CRISPR disruption reveals a role for RNase MRP RNA in human preribosomal RNA processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKX963

The splicing-factor related protein SFPQ/PSF interacts with RAD51D and is necessary for homology-directed repair and sister chromatid cohesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKX963

Involvement of p54(nrb), a PSF partner protein, in DNA double-strand break repair and radioresistance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKX963

SFPQ•NONO and XLF function separately and together to promote DNA double-strand break repair via canonical nonhomologous end joining

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKX963

RNA-binding protein RBM14 regulates dissociation and association of non-homologous end joining proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKX963

Two familial ALS proteins function in prevention/repair of transcription-associated DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKX963

APE1/Ref-1 interacts with NPM1 within nucleoli and plays a role in the rRNA quality control process.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKX963

Identification of Apurinic/apyrimidinic endonuclease 1 (APE1) as the endoribonuclease that cleaves c-myc mRNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKX963

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKX963

Widespread cleavage of A-to-I hyperediting substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKX963

DHX9 suppresses RNA processing defects originating from the Alu invasion of the human genome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKX963

Critical lysine residues within the overlooked N-terminal domain of human APE1 regulate its biological functions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKX963

Sumoylation of nucleophosmin/B23 regulates its subcellular localization, mediating cell proliferation and survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKX963

Mapping a nucleolar targeting sequence of an RNA binding nucleolar protein, Nop25

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKX963

Protein B23/nucleophosmin/numatrin nuclear dynamics in relation to protein kinase CK2 and apoptotic activity in prostate cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKX963

Human DNA helicase IV is nucleolin, an RNA helicase modulated by phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKX963

Mammalian DEAD box protein Ddx51 acts in 3' end maturation of 28S rRNA by promoting the release of U8 snoRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKX963

DEAD-box helicase DDX27 regulates 3' end formation of ribosomal 47S RNA and stably associates with the PeBoW-complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKX963

The RNA helicase Ddx5/p68 binds to hUpf3 and enhances NMD of Ddx17/p72 and Smg5 mRNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKX963

DHX9 helicase is involved in preventing genomic instability induced by alternatively structured DNA in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKX963

RNAi screening uncovers Dhx9 as a modifier of ABT-737 resistance in an Eμ-myc/Bcl-2 mouse model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKX963

Ribosome biogenesis and control of cell proliferation: p53 is not alone

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKX963

The DNA repair activity of human redox/repair protein APE/Ref-1 is inactivated by phosphorylation

21 January 2018

1 reference

12 December 2020

Mechanism of action of eukaryotic topoisomerase II and drugs targeted to the enzyme

1 reference

12 December 2020

Chk1 is an essential kinase that is regulated by Atr and required for the G(2)/M DNA damage checkpoint

1 reference

12 December 2020

An architectural role for a nuclear noncoding RNA: NEAT1 RNA is essential for the structure of paraspeckles

1 reference

12 December 2020

A genome-wide siRNA screen reveals diverse cellular processes and pathways that mediate genome stability

1 reference

12 December 2020

Rrp17p is a eukaryotic exonuclease required for 5' end processing of Pre-60S ribosomal RNA

1 reference

12 December 2020

1 reference

12 December 2020

Human senataxin resolves RNA/DNA hybrids formed at transcriptional pause sites to promote Xrn2-dependent termination

1 reference

12 December 2020

iProphet: multi-level integrative analysis of shotgun proteomic data improves peptide and protein identification rates and error estimates

1 reference

12 December 2020

The evolutionarily conserved protein Las1 is required for pre-rRNA processing at both ends of ITS2

1 reference

12 December 2020

Improved methodology for the affinity isolation of human protein complexes expressed at near endogenous levels.

1 reference

12 December 2020

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts

1 reference

12 December 2020

P-bodies and stress granules: possible roles in the control of translation and mRNA degradation

1 reference

12 December 2020

The intersection between DNA damage response and cell death pathways

1 reference

12 December 2020

Pre-mRNA processing factors meet the DNA damage response

1 reference

12 December 2020

The complexity of human ribosome biogenesis revealed by systematic nucleolar screening of Pre-rRNA processing factors

1 reference

12 December 2020

Double-strand break repair: 53BP1 comes into focus

1 reference

12 December 2020

PRP19 transforms into a sensor of RPA-ssDNA after DNA damage and drives ATR activation via a ubiquitin-mediated circuitry

1 reference

12 December 2020

The roles of SSU processome components and surveillance factors in the initial processing of human ribosomal RNA.

1 reference

12 December 2020

RNA helicase DDX21 coordinates transcription and ribosomal RNA processing

1 reference

12 December 2020

Nucleolin and nucleophosmin: nucleolar proteins with multiple functions in DNA repair

1 reference

12 December 2020

DNA-Damage Response RNA-Binding Proteins (DDRBPs): Perspectives from a New Class of Proteins and Their RNA Targets

1 reference

12 December 2020

The G-patch protein NF-κB-repressing factor mediates the recruitment of the exonuclease XRN2 and activation of the RNA helicase DHX15 in human ribosome biogenesis.

1 reference

12 December 2020

Identifiers

DOI

10.1093/NAR/GKX963

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29069457%20AND%20SRC:MED&resulttype=core&format=json

release_b7palkbmirdxrcfosfzq7uy5ee

8 April 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/b7palkbmirdxrcfosfzq7uy5ee

24 November 2022

mapped directly with Wikidata item

1 reference