Kinase switching in mesenchymal-like non-small cell lung cancer lines contributes to EGFR inhibitor resistance through pathway redundancy (Q46434108)

22 December 2017

title

Kinase switching in mesenchymal-like non-small cell lung cancer lines contributes to EGFR inhibitor resistance through pathway redundancy (English)

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22 December 2017

non-small-cell lung carcinoma

main subject

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Stuart Thomson

1

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22 December 2017

Filippo Petti

2

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22 December 2017

Izabela Sujka-Kwok

3

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22 December 2017

David Epstein

4

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22 December 2017

John D Haley

5

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22 December 2017

publication date

12 August 2008

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22 December 2017

Clinical & Experimental Metastasis

published in

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22 December 2017

volume

25

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22 December 2017

page(s)

843-854

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22 December 2017

issue

8

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22 December 2017

https://scigraph.springernature.com/pub.10.1007/s10585-008-9200-4

exact match

0 references

cites work

Convenient and versatile subcellular extraction procedure, that facilitates classical protein expression profiling and functional protein analysis

1 reference

12 December 2020

Epithelial to mesenchymal transition predicts gefitinib resistance in cell lines of head and neck squamous cell carcinoma and non-small cell lung carcinoma

1 reference

12 December 2020

The Paragon Algorithm, a next generation search engine that uses sequence temperature values and feature probabilities to identify peptides from tandem mass spectra.

1 reference

12 December 2020

Opinion: migrating cancer stem cells - an integrated concept of malignant tumour progression

1 reference

12 December 2020

Reporting protein identification data: the next generation of guidelines.

1 reference

12 December 2020

Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype?

1 reference

12 December 2020

Frequent down-regulation of E-cadherin by genetic and epigenetic changes in the malignant progression of hepatocellular carcinomas

1 reference

12 December 2020

Cool-1 functions as an essential regulatory node for EGF receptor- and Src-mediated cell growth

1 reference

12 December 2020

Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer

1 reference

12 December 2020

A signaling pathway leading to metastasis is controlled by N-cadherin and the FGF receptor

1 reference

12 December 2020

Antiangiogenic and antitumor activity of a selective PDGFR tyrosine kinase inhibitor, CP-673,451.

1 reference

12 December 2020

Downregulation of caveolin-1 function by EGF leads to the loss of E-cadherin, increased transcriptional activity of beta-catenin, and enhanced tumor cell invasion.

1 reference

12 December 2020

Expression profiling of epithelial plasticity in tumor progression

1 reference

12 December 2020

Anti-apoptotic role of TWIST and its association with Akt pathway in mediating taxol resistance in nasopharyngeal carcinoma cells

1 reference

12 December 2020

Phosphotyrosine signaling networks in epidermal growth factor receptor overexpressing squamous carcinoma cells

1 reference

12 December 2020

Loss of homotypic cell adhesion by epithelial-mesenchymal transition or mutation limits sensitivity to epidermal growth factor receptor inhibition

1 reference

12 December 2020

Molecular correlates of gefitinib responsiveness in human bladder cancer cells

1 reference

12 December 2020

Specific receptors for platelet-derived growth factor on cells derived from connective tissue and glia

1 reference

12 December 2020

Restoring E-cadherin expression increases sensitivity to epidermal growth factor receptor inhibitors in lung cancer cell lines.

1 reference

12 December 2020

Temporal quantitation of mutant Kit tyrosine kinase signaling attenuated by a novel thiophene kinase inhibitor OSI-930.

1 reference

12 December 2020

Insulin-like growth factor-I receptor signalling and acquired resistance to gefitinib (ZD1839; Iressa) in human breast and prostate cancer cells

1 reference

12 December 2020

Tyrosine phosphorylation of p145met mediated by EGFR and Src is required for serum-independent survival of human bladder carcinoma cells

1 reference

12 December 2020

Cancer metastasis: building a framework

1 reference

12 December 2020

Changes in cytoskeletal protein composition indicative of an epithelial-mesenchymal transition in human micrometastatic and primary breast carcinoma cells

1 reference

12 December 2020

Epithelial versus mesenchymal phenotype determines in vitro sensitivity and predicts clinical activity of erlotinib in lung cancer patients

1 reference

12 December 2020

Role of basic fibroblast growth factor-2 in epithelial-mesenchymal transformation

1 reference

12 December 2020

Identification and prognostic significance of an epithelial-mesenchymal transition expression profile in human bladder tumors

1 reference

12 December 2020

New signals from the invasive front

1 reference

12 December 2020

Multiplexed protein quantitation in Saccharomyces cerevisiae using amine-reactive isobaric tagging reagents

1 reference

12 December 2020

Heterodimerization of insulin-like growth factor receptor/epidermal growth factor receptor and induction of survivin expression counteract the antitumor action of erlotinib.

1 reference

12 December 2020

Induction by transforming growth factor-beta1 of epithelial to mesenchymal transition is a rare event in vitro

1 reference

12 December 2020

A causal role for E-cadherin in the transition from adenoma to carcinoma

1 reference

12 December 2020

MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling

1 reference

12 December 2020

Targets of fibroblast growth factor 1 (FGF-1) and FGF-2 signaling involved in the invasive and tumorigenic behavior of carcinoma cells

1 reference

12 December 2020

Inactivation of Akt by the epidermal growth factor receptor inhibitor erlotinib is mediated by HER-3 in pancreatic and colorectal tumor cell lines and contributes to erlotinib sensitivity

1 reference

12 December 2020

TGF-beta1 and Ha-Ras collaborate in modulating the phenotypic plasticity and invasiveness of epithelial tumor cells

1 reference

12 December 2020

Epithelial to mesenchymal transition is a determinant of sensitivity of non-small-cell lung carcinoma cell lines and xenografts to epidermal growth factor receptor inhibition

1 reference

12 December 2020

Insulin-like growth factor receptor I mediates resistance to anti-epidermal growth factor receptor therapy in primary human glioblastoma cells through continued activation of phosphoinositide 3-kinase signaling

1 reference

12 December 2020

Heterogeneous expression of Wnt/beta-catenin target genes within colorectal cancer

1 reference

12 December 2020

Hepatocyte growth factor induces cell scattering through MAPK/Egr-1-mediated upregulation of Snail

1 reference

12 December 2020

Autocrine PDGFR signaling promotes mammary cancer metastasis

1 reference

12 December 2020

OSI-930: a novel selective inhibitor of Kit and kinase insert domain receptor tyrosine kinases with antitumor activity in mouse xenograft models

1 reference

12 December 2020

Snail blocks the cell cycle and confers resistance to cell death

1 reference

12 December 2020

The transcriptional repressor Snail promotes mammary tumor recurrence

1 reference

12 December 2020

Epithelial-mesenchymal transitions in tumour progression

1 reference

12 December 2020

Signal pathway profiling of epithelial and stromal compartments of colonic carcinoma reveals epithelial-mesenchymal transition

1 reference

12 December 2020

Silencing of the E-cadherin invasion-suppressor gene by CpG methylation in human carcinomas

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12 December 2020

10.1007/S10585-008-9200-4

Identifiers

DOI

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22 December 2017

PubMed ID

18696232

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22 December 2017