Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype? (Q29547559)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17508028%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

title

Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype? (English)

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=17508028

23 April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17508028%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

1 reference

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17508028%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

David Olmeda

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17508028%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

author name string

Amparo Cano

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17508028%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

publication date

17 May 2007

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17508028%20AND%20SRC:MED&resulttype=core&format=json

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=17508028

30 December 2019

language of work or name

1 reference

23 April 2017

published in

Nature Reviews Cancer

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=17508028

23 April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17508028%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

volume

7

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=17508028

23 April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17508028%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

issue

6

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=17508028

23 April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17508028%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

page(s)

415-428

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17508028%20AND%20SRC:MED&resulttype=core&format=json

publication type of scholarly work

30 December 2019

review article

1 reference

Complex networks orchestrate epithelial-mesenchymal transitions

cites work

1 reference

Epithelial-mesenchymal transitions in tumour progression

31 March 2020

1 reference

Cancer metastasis: building a framework

31 March 2020

1 reference

New potential therapeutic targets to combat epithelial tumor invasion

31 March 2020

1 reference

The fallacy of epithelial mesenchymal transition in neoplasia

31 March 2020

1 reference

Reassessing epithelial to mesenchymal transition as a prerequisite for carcinoma invasion and metastasis

31 March 2020

1 reference

The Snail genes as inducers of cell movement and survival: implications in development and cancer.

31 March 2020

1 reference

The transcription factor snail is a repressor of E-cadherin gene expression in epithelial tumour cells

31 March 2020

1 reference

The transcription factor snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression

31 March 2020

1 reference

The transcription factor Slug represses E-cadherin expression and induces epithelial to mesenchymal transitions: a comparison with Snail and E47 repressors

31 March 2020

1 reference

The two-handed E box binding zinc finger protein SIP1 downregulates E-cadherin and induces invasion

31 March 2020

1 reference

DeltaEF1 is a transcriptional repressor of E-cadherin and regulates epithelial plasticity in breast cancer cells

31 March 2020

1 reference

A new role for E12/E47 in the repression of E-cadherin expression and epithelial-mesenchymal transitions.

31 March 2020

1 reference

Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis

31 March 2020

1 reference

The snail superfamily of zinc-finger transcription factors

31 March 2020

1 reference

Unraveling signalling cascades for the Snail family of transcription factors

31 March 2020

1 reference

Molecular requirements for epithelial-mesenchymal transition during tumor progression

31 March 2020

1 reference

Downregulation of caveolin-1 function by EGF leads to the loss of E-cadherin, increased transcriptional activity of beta-catenin, and enhanced tumor cell invasion

31 March 2020

1 reference

Regulation of Snail transcription during epithelial to mesenchymal transition of tumor cells

31 March 2020

1 reference

Transforming growth factor beta-1 induces snail transcription factor in epithelial cell lines: mechanisms for epithelial mesenchymal transitions.

31 March 2020

1 reference

Notch promotes epithelial-mesenchymal transition during cardiac development and oncogenic transformation

31 March 2020

1 reference

Integration of TGF-beta/Smad and Jagged1/Notch signalling in epithelial-to-mesenchymal transition

31 March 2020

1 reference

Cooperation between snail and LEF-1 transcription factors is essential for TGF-beta1-induced epithelial-mesenchymal transition

31 March 2020

1 reference

Autoregulation of E-cadherin expression by cadherin-cadherin interactions: the roles of beta-catenin signaling, Slug, and MAPK

31 March 2020

1 reference

Cooperative action of Sox9, Snail2 and PKA signaling in early neural crest development

31 March 2020

1 reference

Cloning and characterization of three Xenopus slug promoters reveal direct regulation by Lef/beta-catenin signaling.

31 March 2020

1 reference

Transforming growth factor-beta employs HMGA2 to elicit epithelial-mesenchymal transition.

31 March 2020

1 reference

Repression of prostaglandin dehydrogenase by epidermal growth factor and snail increases prostaglandin E2 and promotes cancer progression

31 March 2020

1 reference

Cyclooxygenase-2-dependent regulation of E-cadherin: prostaglandin E(2) induces transcriptional repressors ZEB1 and snail in non-small cell lung cancer.

31 March 2020

1 reference

Endothelin-1 promotes epithelial-to-mesenchymal transition in human ovarian cancer cells

31 March 2020

1 reference

Vascular endothelial growth factor receptor-1 activation mediates epithelial to mesenchymal transition in human pancreatic carcinoma cells

31 March 2020

1 reference

Autocrine motility factor signaling enhances pancreatic cancer metastasis

31 March 2020

1 reference

Raf 1 represses expression of the tight junction protein occludin via activation of the zinc-finger transcription factor slug

31 March 2020

1 reference

Calreticulin represses E-cadherin gene expression in Madin-Darby canine kidney cells via Slug

31 March 2020

1 reference

VHL promotes E2 box-dependent E-cadherin transcription by HIF-mediated regulation of SIP1 and snail

31 March 2020

1 reference

Rac1b and reactive oxygen species mediate MMP-3-induced EMT and genomic instability

31 March 2020

1 reference

Laminin-5 with transforming growth factor-beta1 induces epithelial to mesenchymal transition in hepatocellular carcinoma

31 March 2020

1 reference

Androgen regulation of prostasin gene expression is mediated by sterol-regulatory element-binding proteins and SLUG

31 March 2020

1 reference

MTA3, a Mi-2/NuRD complex subunit, regulates an invasive growth pathway in breast cancer

31 March 2020

1 reference

Transcriptional activation by the zinc-finger homeodomain protein delta EF1 in estrogen signaling cascades

31 March 2020

1 reference

Snail1 transcriptional repressor binds to its own promoter and controls its expression

31 March 2020

1 reference

Regulation of Slug transcription in embryonic ectoderm by beta-catenin-Lef/Tcf and BMP-Smad signaling

31 March 2020

1 reference

Glycogen synthase kinase-3 is an endogenous inhibitor of Snail transcription: implications for the epithelial-mesenchymal transition

31 March 2020

1 reference

Hepatocyte growth factor induces cell scattering through MAPK/Egr-1-mediated upregulation of Snail

31 March 2020

1 reference

Snail/slug family of repressors: slowly going into the fast lane of development and cancer

31 March 2020

1 reference

Id family of helix-loop-helix proteins in cancer

31 March 2020

1 reference

Id proteins in development, cell cycle and cancer

31 March 2020

1 reference

Opposing functions of ZEB proteins in the regulation of the TGFbeta/BMP signaling pathway

31 March 2020

1 reference

Transcriptional regulation of cadherins during development and carcinogenesis.

31 March 2020

1 reference

Human Slug is a repressor that localizes to sites of active transcription

31 March 2020

1 reference

Snail mediates E-cadherin repression by the recruitment of the Sin3A/histone deacetylase 1 (HDAC1)/HDAC2 complex

31 March 2020

1 reference

Regulation of BRCA2 gene expression by the SLUG repressor protein in human breast cells

31 March 2020

1 reference

Human SLUG does not directly bind to CtBP1

31 March 2020

1 reference

Coordinated histone modifications mediated by a CtBP co-repressor complex

31 March 2020

1 reference

Interaction between Smad-interacting protein-1 and the corepressor C-terminal binding protein is dispensable for transcriptional repression of E-cadherin

31 March 2020

1 reference

The expression levels of the transcriptional regulators p300 and CtBP modulate the correlations between SNAIL, ZEB1, E-cadherin and vitamin D receptor in human colon carcinomas.

31 March 2020

1 reference

Regulation of Smad signaling through a differential recruitment of coactivators and corepressors by ZEB proteins

31 March 2020

1 reference

Nuclear speckle-associated protein Pnn/DRS binds to the transcriptional corepressor CtBP and relieves CtBP-mediated repression of the E-cadherin gene

31 March 2020

1 reference

Pc2-mediated sumoylation of Smad-interacting protein 1 attenuates transcriptional repression of E-cadherin

31 March 2020

1 reference

Acetylation by p300 regulates nuclear localization and function of the transcriptional corepressor CtBP2.

31 March 2020

1 reference

A role for Id in the regulation of TGF-beta-induced epithelial-mesenchymal transdifferentiation

31 March 2020

1 reference

Phosphorylation regulates the subcellular location and activity of the snail transcriptional repressor

31 March 2020

1 reference

Pak1 phosphorylation of snail, a master regulator of epithelial-to-mesenchyme transition, modulates snail's subcellular localization and functions

31 March 2020

1 reference

Zinc transporter LIVI controls epithelial-mesenchymal transition in zebrafish gastrula organizer

31 March 2020

1 reference

Dual regulation of Snail by GSK-3beta-mediated phosphorylation in control of epithelial-mesenchymal transition

31 March 2020

1 reference

A Wnt-Axin2-GSK3beta cascade regulates Snail1 activity in breast cancer cells

31 March 2020

1 reference

A molecular role for lysyl oxidase-like 2 enzyme in snail regulation and tumor progression

31 March 2020

1 reference

Switching on-off Snail: LOXL2 versus GSK3beta

31 March 2020

1 reference

Slug stability is dynamically regulated during neural crest development by the F-box protein Ppa.

31 March 2020

1 reference

E47 phosphorylation by p38 MAPK promotes MyoD/E47 association and muscle-specific gene transcription

31 March 2020

1 reference

Serine/Threonine kinases 3pK and MAPK-activated protein kinase 2 interact with the basic helix-loop-helix transcription factor E47 and repress its transcriptional activity

31 March 2020

1 reference

Identification of the E2A gene products as regulatory targets of the G1 cyclin-dependent kinases

31 March 2020

1 reference

Notch-induced E2A ubiquitination and degradation are controlled by MAP kinase activities

31 March 2020

1 reference

Genetic profiling of epithelial cells expressing E-cadherin repressors reveals a distinct role for Snail, Slug, and E47 factors in epithelial-mesenchymal transition

31 March 2020

1 reference

Mouse cDNA microarray analysis uncovers Slug targets in mouse embryonic fibroblasts

31 March 2020

1 reference

SIP1/ZEB2 induces EMT by repressing genes of different epithelial cell-cell junctions

31 March 2020

1 reference

Snail activation disrupts tissue homeostasis and induces fibrosis in the adult kidney

31 March 2020

1 reference

Snail controls differentiation of hepatocytes by repressing HNF4α expression

31 March 2020

1 reference

The transcription factor snail induces tumor cell invasion through modulation of the epithelial cell differentiation program.

31 March 2020

1 reference

The transcription factor SNAIL represses vitamin D receptor expression and responsiveness in human colon cancer.

31 March 2020

1 reference

Aberrant expression of the transcription factors snail and slug alters the response to genotoxic stress

31 March 2020

1 reference

Slug antagonizes p53-mediated apoptosis of hematopoietic progenitors by repressing puma

31 March 2020

1 reference

Repression of Na,K-ATPase beta1-subunit by the transcription factor snail in carcinoma

31 March 2020

1 reference

A ubiquitin ligase, skeletrophin, is a negative regulator of melanoma invasion

31 March 2020

1 reference

Snail blocks the cell cycle and confers resistance to cell death

31 March 2020

1 reference

Mouse Snail family transcription repressors regulate chondrocyte, extracellular matrix, type II collagen, and aggrecan

31 March 2020

1 reference

Slug regulates integrin expression and cell proliferation in human epidermal keratinocytes

31 March 2020

1 reference

Snail regulates p21(WAF/CIP1) expression in cooperation with E2A and Twist

31 March 2020

1 reference

Snail induction of epithelial to mesenchymal transition in tumor cells is accompanied by MUC1 repression and ZEB1 expression

31 March 2020

1 reference

Regulation of ocular lens development by Smad-interacting protein 1 involving Foxe3 activation

31 March 2020

1 reference

N-cadherin gene expression in prostate carcinoma is modulated by integrin-dependent nuclear translocation of Twist1.

31 March 2020

1 reference

Regulation of cellular senescence and p16(INK4a) expression by Id1 and E47 proteins in human diploid fibroblast

31 March 2020

1 reference

Smooth muscle alpha-actin gene requires two E-boxes for proper expression in vivo and is a target of class I basic helix-loop-helix proteins

31 March 2020

1 reference

Upregulation of MMP-9 in MDCK epithelial cell line in response to expression of the Snail transcription factor

31 March 2020

1 reference

New mode of DNA binding of multi-zinc finger transcription factors: deltaEF1 family members bind with two hands to two target sites

31 March 2020

1 reference

Correlation of Snail expression with histological grade and lymph node status in breast carcinomas

31 March 2020

1 reference

Mechanisms of inactivation of E-cadherin in breast carcinoma: modification of the two-hit hypothesis of tumor suppressor gene

31 March 2020

1 reference

Snail and slug play distinct roles during breast carcinoma progression.

31 March 2020

1 reference

Snail, Slug, and Smad-interacting protein 1 as novel parameters of disease aggressiveness in metastatic ovarian and breast carcinoma

31 March 2020

1 reference

The transcriptional repressor Snail promotes mammary tumor recurrence

31 March 2020

1 reference

Expression of the transcription factors snail, slug, and twist and their clinical significance in human breast cancer

31 March 2020

1 reference

Expression of E-cadherin transcriptional regulators in ovarian carcinoma

31 March 2020

1 reference

E-cadherin and vitamin D receptor regulation by SNAIL and ZEB1 in colon cancer: clinicopathological correlations

31 March 2020

1 reference

The transcriptional repressor SNAIL is overexpressed in human colon cancer

31 March 2020

1 reference

Slug expression is an independent prognostic parameter for poor survival in colorectal carcinoma patients

31 March 2020

1 reference

Differential expression of the epithelial-mesenchymal transition regulators snail, SIP1, and twist in gastric cancer

31 March 2020

1 reference

Expression and nuclear localization of Snail, an E-cadherin repressor, in adenocarcinomas of the upper gastrointestinal tract.

31 March 2020

1 reference

Increased NBS1 expression is a marker of aggressive head and neck cancer and overexpression of NBS1 contributes to transformation

31 March 2020

1 reference

Snail accelerates cancer invasion by upregulating MMP expression and is associated with poor prognosis of hepatocellular carcinoma

31 March 2020

1 reference

Transcription repressor slug promotes carcinoma invasion and predicts outcome of patients with lung adenocarcinoma

31 March 2020

1 reference

Expression of Snail, Slug and Sip1 in malignant mesothelioma effusions is associated with matrix metalloproteinase, but not with cadherin expression

31 March 2020

1 reference

E-cadherin mutation and Snail overexpression as alternative mechanisms of E-cadherin inactivation in synovial sarcoma

31 March 2020

1 reference

The melanocyte differentiation program predisposes to metastasis after neoplastic transformation

31 March 2020

1 reference

Biological potential of a functional human SNAIL retrogene.

31 March 2020

1 reference

Expression of Snail protein in tumor-stroma interface

31 March 2020

1 reference

Collagen type I-induced Smad-interacting protein 1 expression downregulates E-cadherin in pancreatic cancer

31 March 2020

1 reference

The transcription factor ZEB1 is aberrantly expressed in aggressive uterine cancers

31 March 2020

1 reference

Twist overexpression induces in vivo angiogenesis and correlates with chromosomal instability in breast cancer

31 March 2020

1 reference

Epigenetic and genetic alterations ofAPCandCDH1genes in lobular breast cancer: Relationships with abnormal E-cadherin and catenin expression and microsatellite instability

31 March 2020

1 reference

Up-regulation of TWIST in prostate cancer and its implication as a therapeutic target

31 March 2020

1 reference

Twist overexpression correlates with hepatocellular carcinoma metastasis through induction of epithelial-mesenchymal transition.

31 March 2020

1 reference

High Twist expression is involved in infiltrative endometrial cancer and affects patient survival

31 March 2020

1 reference

Expression profiling reveals novel pathways in the transformation of melanocytes to melanomas

31 March 2020

1 reference

Reassessment of id1 protein expression in human mammary, prostate, and bladder cancers using a monospecific rabbit monoclonal anti-id1 antibody.

31 March 2020

1 reference

Snail silencing effectively suppresses tumour growth and invasiveness.

31 March 2020

1 reference

A signaling pathway involving TGF-beta2 and snail in hair follicle morphogenesis

31 March 2020

1 reference

The C. elegans cell death specification gene ces-1 encodes a snail family zinc finger protein

31 March 2020

1 reference

SLUG, a ces-1-related zinc finger transcription factor gene with antiapoptotic activity, is a downstream target of the E2A-HLF oncoprotein

31 March 2020

1 reference

Slug, a highly conserved zinc finger transcriptional repressor, protects hematopoietic progenitor cells from radiation-induced apoptosis in vivo.

31 March 2020

1 reference

The radioresistance biological function of the SCF/kit signaling pathway is mediated by the zinc-finger transcription factor Slug

31 March 2020

1 reference

Induction of stem cell factor/c-Kit/slug signal transduction in multidrug-resistant malignant mesothelioma cells

31 March 2020

1 reference

A twist for survival and cancer progression

31 March 2020

1 reference

Identification of a novel function of TWIST, a bHLH protein, in the development of acquired taxol resistance in human cancer cells

31 March 2020

1 reference

Snail in the frame of malignant tumor recurrence

31 March 2020

1 reference

Opinion: migrating cancer stem cells - an integrated concept of malignant tumour progression

31 March 2020

1 reference

Of extracellular matrix, scaffolds, and signaling: tissue architecture regulates development, homeostasis, and cancer.

31 March 2020

1 reference

Expression of Frzb/secreted Frizzled-related protein 3, a secreted Wnt antagonist, in human androgen-independent prostate cancer PC-3 cells suppresses tumor growth and cellular invasiveness

31 March 2020

1 reference

NF-kappaB represses E-cadherin expression and enhances epithelial to mesenchymal transition of mammary epithelial cells: potential involvement of ZEB-1 and ZEB-2.

31 March 2020

1 reference

Snail and E47 repressors of E-cadherin induce distinct invasive and angiogenic properties in vivo

31 March 2020

1 reference

Snail-dependent and -independent epithelial-mesenchymal transition in oral squamous carcinoma cells

31 March 2020

1 reference

The transcription factors Slug and Snail act as repressors of Claudin-1 expression in epithelial cells.

31 March 2020

1 reference

Tumour-cell invasion and migration: diversity and escape mechanisms

31 March 2020

1 reference

Developmental transcription factor slug is required for effective re-epithelialization by adult keratinocytes.

31 March 2020

1 reference

TGF-beta and epithelial-to-mesenchymal transitions

31 March 2020

1 reference

Regulation of E-cadherin expression by VHL and hypoxia-inducible factor

31 March 2020

1 reference

Hypoxia-inducible factor-1-dependent repression of E-cadherin in von Hippel-Lindau tumor suppressor-null renal cell carcinoma mediated by TCF3, ZFHX1A, and ZFHX1B.

31 March 2020

1 reference

Snail and Slug are major determinants of ovarian cancer invasiveness at the transcription level

31 March 2020

1 reference

Hypoxia Attenuates the Expression of E-Cadherin via Up-Regulation of SNAIL in Ovarian Carcinoma Cells

31 March 2020

1 reference

RETRACTED: Lysyl oxidase is essential for hypoxia-induced metastasis

31 March 2020

1 reference

Hypoxia signalling in cancer and approaches to enforce tumour regression

31 March 2020

1 reference

The Mouse Snail Gene Encodes a Key Regulator of the Epithelial-Mesenchymal Transition

31 March 2020

1 reference

Snail family genes are required for left-right asymmetry determination, but not neural crest formation, in mice

31 March 2020

1 reference

Differential expression and function of members of the zfh-1 family of zinc finger/homeodomain repressors

31 March 2020

1 reference

Mice lacking ZFHX1B, the gene that codes for Smad-interacting protein-1, reveal a role for multiple neural crest cell defects in the etiology of Hirschsprung disease-mental retardation syndrome

31 March 2020

1 reference

Helix-loop-helix proteins: regulators of transcription in eucaryotic organisms

31 March 2020

1 reference

Crystal structure of transcription factor E47: E-box recognition by a basic region helix-loop-helix dimer

31 March 2020

1 reference

A new transcriptional-activation motif restricted to a class of helix-loop-helix proteins is functionally conserved in both yeast and mammalian cells

31 March 2020

1 reference

FOXO transcription factors cooperate with delta EF1 to activate growth suppressive genes in B lymphocytes

31 March 2020

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=17508028

31 March 2020

Identifiers

3 references

23 April 2017

Consolidated OpenCitations Corpus – April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17508028%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

30 December 2019

1025092385

0 references

1 reference

Consolidated OpenCitations Corpus – April 2017

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=17508028

3 references

23 April 2017

Consolidated OpenCitations Corpus – April 2017