Liver X receptor activation inhibits osteoclastogenesis by suppressing NF-κB activity and c-Fos induction and prevents inflammatory bone loss in mice (Q46187570)

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English	Liver X receptor activation inhibits osteoclastogenesis by suppressing NF-κB activity and c-Fos induction and prevents inflammatory bone loss in mice	scientific article

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scholarly article

1 reference

Europe PubMed Central

20 December 2017

http://europepmc.org/abstract/MED/23657115

Liver X receptor activation inhibits osteoclastogenesis by suppressing NF-κB activity and c-Fos induction and prevents inflammatory bone loss in mice (English)

1 reference

Europe PubMed Central

20 December 2017

http://europepmc.org/abstract/MED/23657115

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author name string

Hyun-Ju Kim

1

1 reference

Europe PubMed Central

20 December 2017

http://europepmc.org/abstract/MED/23657115

Kyung-Ae Yoon

2

1 reference

Europe PubMed Central

20 December 2017

http://europepmc.org/abstract/MED/23657115

Hye-Jin Yoon

3

1 reference

Europe PubMed Central

20 December 2017

http://europepmc.org/abstract/MED/23657115

Jung Min Hong

4

1 reference

Europe PubMed Central

20 December 2017

http://europepmc.org/abstract/MED/23657115

Min-Jung Lee

5

1 reference

Europe PubMed Central

20 December 2017

http://europepmc.org/abstract/MED/23657115

In-Kyu Lee

6

1 reference

Europe PubMed Central

20 December 2017

http://europepmc.org/abstract/MED/23657115

Shin-Yoon Kim

7

1 reference

Europe PubMed Central

20 December 2017

http://europepmc.org/abstract/MED/23657115

publication date

8 May 2013

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Europe PubMed Central

20 December 2017

http://europepmc.org/abstract/MED/23657115

Journal of Leukocyte Biology

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Europe PubMed Central

20 December 2017

http://europepmc.org/abstract/MED/23657115

94

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20 December 2017

http://europepmc.org/abstract/MED/23657115

1

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20 December 2017

http://europepmc.org/abstract/MED/23657115

99-107

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Europe PubMed Central

20 December 2017

http://europepmc.org/abstract/MED/23657115

A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell function

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https://api.crossref.org/works/10.1189%2FJLB.1112601

21 January 2018

Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation

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https://api.crossref.org/works/10.1189%2FJLB.1112601

21 January 2018

TRANCE (tumor necrosis factor [TNF]-related activation-induced cytokine), a new TNF family member predominantly expressed in T cells, is a dendritic cell-specific survival factor

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https://api.crossref.org/works/10.1189%2FJLB.1112601

21 January 2018

Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL

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https://api.crossref.org/works/10.1189%2FJLB.1112601

21 January 2018

Osteoclast-derived activity in the coupling of bone formation to resorption.

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https://api.crossref.org/works/10.1189%2FJLB.1112601

21 January 2018

Osteoclast differentiation and activation

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https://api.crossref.org/works/10.1189%2FJLB.1112601

21 January 2018

Update on bone anabolics in osteoporosis treatment: rationale, current status, and perspectives

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https://api.crossref.org/works/10.1189%2FJLB.1112601

21 January 2018

Molecular regulation of osteoclast activity

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https://api.crossref.org/works/10.1189%2FJLB.1112601

21 January 2018

Osteoclasts: what do they do and how do they do it?

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https://api.crossref.org/works/10.1189%2FJLB.1112601

21 January 2018

Genetic regulation of osteoclast development and function

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https://api.crossref.org/works/10.1189%2FJLB.1112601

21 January 2018

The osteoclast: friend or foe?

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https://api.crossref.org/works/10.1189%2FJLB.1112601

21 January 2018

The molecular understanding of osteoclast differentiation

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https://api.crossref.org/works/10.1189%2FJLB.1112601

21 January 2018

Role of RANKL in physiological and pathological bone resorption and therapeutics targeting the RANKL-RANK signaling system

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https://api.crossref.org/works/10.1189%2FJLB.1112601

21 January 2018

Requirement for NF-kappaB in osteoclast and B-cell development

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https://api.crossref.org/works/10.1189%2FJLB.1112601

21 January 2018

Osteopetrosis in mice lacking NF-kappaB1 and NF-kappaB2.

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https://api.crossref.org/works/10.1189%2FJLB.1112601

21 January 2018

Bone development and inflammatory disease is regulated by AP-1 (Fos/Jun).

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https://api.crossref.org/works/10.1189%2FJLB.1112601

21 January 2018

New regulation mechanisms of osteoclast differentiation

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https://api.crossref.org/works/10.1189%2FJLB.1112601

21 January 2018

The role of orphan nuclear receptors in the regulation of cholesterol homeostasis

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https://api.crossref.org/works/10.1189%2FJLB.1112601

21 January 2018

Liver X receptor biology and pharmacology: new pathways, challenges and opportunities.

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https://api.crossref.org/works/10.1189%2FJLB.1112601

21 January 2018

Synthetic LXR ligand inhibits the development of atherosclerosis in mice

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https://api.crossref.org/works/10.1189%2FJLB.1112601

21 January 2018

T-0901317, a synthetic liver X receptor ligand, inhibits development of atherosclerosis in LDL receptor-deficient mice

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1112601

21 January 2018

Ligand activation of LXR beta reverses atherosclerosis and cellular cholesterol overload in mice lacking LXR alpha and apoE

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https://api.crossref.org/works/10.1189%2FJLB.1112601

21 January 2018

Reciprocal regulation of inflammation and lipid metabolism by liver X receptors

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https://api.crossref.org/works/10.1189%2FJLB.1112601

21 January 2018

Liver X receptor agonist prevents the evolution of collagen-induced arthritis in mice.

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1112601

21 January 2018

LXR modulation blocks prostaglandin E2 production and matrix degradation in cartilage and alleviates pain in a rat osteoarthritis model

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https://api.crossref.org/works/10.1189%2FJLB.1112601

21 January 2018

Short-term activation of liver X receptors inhibits osteoblasts but long-term activation does not have an impact on murine bone in vivo

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1112601

21 January 2018

Activation of liver X receptor (LXR) inhibits receptor activator of nuclear factor κB ligand (RANKL)-induced osteoclast differentiation in an LXRβ-dependent mechanism

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1112601

21 January 2018

Calpain-6, a target molecule of glucocorticoids, regulates osteoclastic bone resorption via cytoskeletal organization and microtubule acetylation

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1112601

21 January 2018

Liver x receptors in atherosclerosis and inflammation

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https://api.crossref.org/works/10.1189%2FJLB.1112601

21 January 2018

PPARγ in bone homeostasis

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https://api.crossref.org/works/10.1189%2FJLB.1112601

21 January 2018

PPAR-gamma regulates osteoclastogenesis in mice

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https://api.crossref.org/works/10.1189%2FJLB.1112601

21 January 2018

Cross-talk between peroxisome proliferator-activated receptor (PPAR) alpha and liver X receptor (LXR) in nutritional regulation of fatty acid metabolism. I. PPARs suppress sterol regulatory element binding protein-1c promoter through inhibition of L

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1112601

21 January 2018

Transforming growth factor-beta induces expression of receptor activator of NF-kappa B ligand in vascular endothelial cells derived from bone

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1112601

21 January 2018

Induction and activation of the transcription factor NFATc1 (NFAT2) integrate RANKL signaling in terminal differentiation of osteoclasts

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1112601

21 January 2018

Liver x receptor agonists inhibit cytokine-induced osteopontin expression in macrophages through interference with activator protein-1 signaling pathways

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1112601

21 January 2018

A PPAR gamma-LXR-ABCA1 pathway in macrophages is involved in cholesterol efflux and atherogenesis

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1112601

21 January 2018

PPARgamma promotes monocyte/macrophage differentiation and uptake of oxidized LDL

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1112601

21 January 2018

PPAR-gamma agonists inhibit production of monocyte inflammatory cytokines

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1112601

21 January 2018

Liver X receptor and peroxisome proliferator-activated receptor as integrators of lipid homeostasis and immunity

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1112601

21 January 2018

The orphan nuclear hormone receptor LXR alpha interacts with the peroxisome proliferator-activated receptor and inhibits peroxisome proliferator signaling

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1112601

21 January 2018

Parallel SUMOylation-dependent pathways mediate gene- and signal-specific transrepression by LXRs and PPARgamma

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1112601

21 January 2018

Chronic activation of liver X receptor induces beta-cell apoptosis through hyperactivation of lipogenesis: liver X receptor-mediated lipotoxicity in pancreatic beta-cells.

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1112601

21 January 2018

Activation of liver X receptors and retinoid X receptors induces growth arrest and apoptosis in insulin-secreting cells.

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1112601

21 January 2018

Regulation of osteoclast apoptosis by ubiquitylation of proapoptotic BH3-only Bcl-2 family member Bim.

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1112601

21 January 2018

Cholesterol-sensing receptors, liver X receptor alpha and beta, have novel and distinct roles in osteoclast differentiation and activation.

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1112601

21 January 2018

NF-κB p50 and p52 Regulate Receptor Activator of NF-κB Ligand (RANKL) and Tumor Necrosis Factor-induced Osteoclast Precursor Differentiation by Activating c-Fos and NFATc1

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1112601

21 January 2018

Bone and haematopoietic defects in mice lacking c-fos

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1112601

21 January 2018

Identifiers

10.1189/JLB.1112601

1 reference

Europe PubMed Central

20 December 2017

http://europepmc.org/abstract/MED/23657115

1 reference

Europe PubMed Central

20 December 2017

http://europepmc.org/abstract/MED/23657115

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