Inhibition of proteolysis of Delta-like-1 does not promote or reduce T-cell developmental potential (Q46127530)

19 December 2017

title

Inhibition of proteolysis of Delta-like-1 does not promote or reduce T-cell developmental potential (English)

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19 December 2017

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David M Gravano

1

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19 December 2017

Jennifer O Manilay

series ordinal

2

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19 December 2017

publication date

16 March 2010

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19 December 2017

Immunology & Cell Biology

published in

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19 December 2017

volume

88

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19 December 2017

issue

7

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19 December 2017

page(s)

746-753

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19 December 2017

Notch regulation of lymphocyte development and function.

cites work

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.30

A Notch so simple influence on T cell development.

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1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.30

Notch ligand-bearing thymic epithelial cells initiate and sustain Notch signaling in thymocytes independently of T cell receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.30

The canonical Notch signaling pathway: unfolding the activation mechanism

21 January 2018

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https://api.crossref.org/works/10.1038%2FICB.2010.30

ADAM proteases: ligand processing and modulation of the Notch pathway

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https://api.crossref.org/works/10.1038%2FICB.2010.30

Notch signalling: a simple pathway becomes complex

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1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.30

Complex proteolytic processing acts on Delta, a transmembrane ligand for Notch, during Drosophila development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.30

RECK modulates Notch signaling during cortical neurogenesis by regulating ADAM10 activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.30

The role of Delta-like 1 shedding in muscle cell self-renewal and differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.30

Proteolytic processing of delta-like 1 by ADAM proteases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.30

The Notch ligands, Jagged and Delta, are sequentially processed by alpha-secretase and presenilin/gamma-secretase and release signaling fragments

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.30

Processing of the notch ligand delta by the metalloprotease Kuzbanian

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.30

Down-regulation of Delta by proteolytic processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.30

Unidirectional Notch signaling depends on continuous cleavage of Delta

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.30

The Notch ligands, Delta1 and Jagged2, are substrates for presenilin-dependent "gamma-secretase" cleavage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.30

The Notch ligand Delta1 is sequentially cleaved by an ADAM protease and gamma-secretase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.30

Notch-induced proteolysis and nuclear localization of the Delta ligand

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.30

The Delta intracellular domain mediates TGF-beta/Activin signaling through binding to Smads and has an important bi-directional function in the Notch-Delta signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.30

The intracellular domain of Notch ligand Delta1 induces cell growth arrest

21 January 2018

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https://api.crossref.org/works/10.1038%2FICB.2010.30

Multiple niches for Notch in cancer: context is everything

21 January 2018

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https://api.crossref.org/works/10.1038%2FICB.2010.30

Deficient T cell fate specification in mice with an induced inactivation of Notch1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.30

Impairment of thymocyte development by dominant-negative Kuzbanian (ADAM-10) is rescued by the Notch ligand, delta-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.30

ADAM10 is essential for proteolytic activation of Notch during thymocyte development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.30

Non-cell autonomous expression of TNF-alpha-converting enzyme ADAM17 is required for normal lymphocyte development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.30

Inactivation of Notch1 impairs VDJbeta rearrangement and allows pre-TCR-independent survival of early alpha beta Lineage Thymocytes.

21 January 2018

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https://api.crossref.org/works/10.1038%2FICB.2010.30

Induction of T cell development from hematopoietic progenitor cells by delta-like-1 in vitro.

21 January 2018

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T-cell development, doing it in a dish.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.30

Delta-1 activation of notch-1 signaling results in HES-1 transactivation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.30

Direct induction of T lymphocyte-specific gene expression by the mammalian Notch signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.30

Notch target Hes5 ensures appropriate Notch induced T- versus B-cell choices in the thymus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.30

Multiple functions of Notch signaling in self-renewing organs and cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.30

Generation of lymphohematopoietic cells from embryonic stem cells in culture

21 January 2018

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https://api.crossref.org/works/10.1038%2FICB.2010.30

Flow cytometric identification of murine neutrophils and monocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.30

Soluble form of Jagged1: unique product of epithelial keratinocytes and a regulator of keratinocyte differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.30

The lateral signal for LIN-12/Notch in C. elegans vulval development comprises redundant secreted and transmembrane DSL proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.30

Fine-tuning Notch1 activation by endocytosis and glycosylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.30

Overexpression of the Notch target genes Hes in vivo induces lymphoid and myeloid alterations

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.30

The Notch signaling pathway: transcriptional regulation at Notch target genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.30

Density of the Notch ligand Delta1 determines generation of B and T cell precursors from hematopoietic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.30

Delta-like 4 is indispensable in thymic environment specific for T cell development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.30

Delta-like 4 is the essential, nonredundant ligand for Notch1 during thymic T cell lineage commitment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.30

Induction of T-cell development from human cord blood hematopoietic stem cells by Delta-like 1 in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.30

Notch signaling requires GATA-2 to inhibit myelopoiesis from embryonic stem cells and primary hemopoietic progenitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.30

Notch signaling specifies megakaryocyte development from hematopoietic stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.30

A gene regulatory network armature for T lymphocyte specification

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.30

Production of high-titer helper-free retroviruses by transient transfection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.30

A ligand-induced extracellular cleavage regulates gamma-secretase-like proteolytic activation of Notch1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.30

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/ICB.2010.30

1 reference

19 December 2017

PubMed ID

20231851

1 reference

19 December 2017