Delta-like 4 is the essential, nonredundant ligand for Notch1 during thymic T cell lineage commitment. (Q36946535)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18824585%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

title

Delta-like 4 is the essential, nonredundant ligand for Notch1 during thymic T cell lineage commitment (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18824585%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

1 reference

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18824585%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

António Duarte

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18824585%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

Freddy Radtke

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18824585%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

author name string

Ute Koch

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18824585%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

Emma Fiorini

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18824585%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

Valerie Besseyrias

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18824585%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

Karin Schuster-Gossler

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18824585%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

Michel Pierres

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18824585%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

Nancy R Manley

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18824585%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

H Robson Macdonald

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18824585%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

language of work or name

English

0 references

publication date

29 September 2008

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18824585%20AND%20SRC:MED&resulttype=core&format=json

Journal of Experimental Medicine

14 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18824585%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

volume

205

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18824585%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

issue

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18824585%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

page(s)

2515-2523

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18824585%20AND%20SRC:MED&resulttype=core&format=json

Specific expression of lacZ and cre recombinase in fetal thymic epithelial cells by multiplex gene targeting at the Foxn1 locus

14 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2571927

Hierarchy of Notch-Delta interactions promoting T cell lineage commitment and maturation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2571927

Regulation of lymphoid development, differentiation, and function by the Notch pathway.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2571927

Haploinsufficiency of delta-like 4 ligand results in embryonic lethality due to major defects in arterial and vascular development.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2571927

Notch ligands Delta 1 and Jagged1 transmit distinct signals to T-cell precursors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2571927

Dosage-sensitive requirement for mouse Dll4 in artery development

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2571927

Analysis of Notch1 function by in vitro T cell differentiation of Pax5 mutant lymphoid progenitors.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2571927

Maintenance of T cell specification and differentiation requires recurrent notch receptor-ligand interactions

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2571927

Delta-like 1 is necessary for the generation of marginal zone B cells but not T cells in vivo

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2571927

Notch2 is preferentially expressed in mature B cells and indispensable for marginal zone B lineage development

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2571927

Induction of T cell development from hematopoietic progenitor cells by delta-like-1 in vitro.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2571927

A novel Notch ligand, Dll4, induces T-cell leukemia/lymphoma when overexpressed in mice by retroviral-mediated gene transfer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2571927

Notch 1-deficient common lymphoid precursors adopt a B cell fate in the thymus.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2571927

Differential effects of Notch ligands Delta-1 and Jagged-1 in human lymphoid differentiation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2571927

Stepwise specification of lymphocyte developmental lineages.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2571927

High-efficiency deleter mice show that FLPe is an alternative to Cre-loxP

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2571927

Expression of the mouse Delta1 gene during organogenesis and fetal development

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2571927

Expression pattern of notch1, 2 and 3 and Jagged1 and 2 in lymphoid and stromal thymus components: distinct ligand-receptor interactions in intrathymic T cell development

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2571927

Defects in limb, craniofacial, and thymic development in Jagged2 mutant mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2571927

Maintenance of somite borders in mice requires the Delta homologue DII1.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2571927

Control points in early T-cell development

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2571927

Inducible gene targeting in mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2571927

Developmental kinetics, turnover, and stimulatory capacity of thymic epithelial cells.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2571927

Three-dimensional architecture of the thymus is required to maintain delta-like expression necessary for inducing T cell development.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2571927

Expression of Dll4 during mouse embryogenesis suggests multiple developmental roles.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2571927

In vivo and in absence of a thymus, the enforced expression of the Notch ligands delta-1 or delta-4 promotes T cell development with specific unique effects.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2571927

Jagged1-dependent Notch signaling is dispensable for hematopoietic stem cell self-renewal and differentiation.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2571927

Regulation of alphabeta/gammadelta T cell lineage commitment and peripheral T cell responses by Notch/RBP-J signaling.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2571927

Instruction of distinct CD4 T helper cell fates by different notch ligands on antigen-presenting cells.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2571927

Entry into the thymic microenvironment triggers Notch activation in the earliest migrant T cell progenitors.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2571927

Inactivation of Notch1 impairs VDJbeta rearrangement and allows pre-TCR-independent survival of early alpha beta Lineage Thymocytes.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2571927

Inactivation of Notch 1 in immature thymocytes does not perturb CD4 or CD8T cell development.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2571927

Shaping of the autoreactive T-cell repertoire by a splice variant of self protein expressed in thymic epithelial cells.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2571927

Deficient T cell fate specification in mice with an induced inactivation of Notch1.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2571927

T cell priming by tissue-derived dendritic cells: new insights from recent murine studies

4 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1084%2FJEM.20080829

Inducible gene knockout of transcription factor recombination signal binding protein-J reveals its essential role in T versus B lineage decision

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18824585

12 December 2020

inferred from PubMed ID database lookup

Lack of Delta like 1 and 4 expressions in nude thymus anlages

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18824585

12 December 2020

inferred from PubMed ID database lookup

Redefining epithelial progenitor potential in the developing thymus

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18824585

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1084/JEM.20080829

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18824585%20AND%20SRC:MED&resulttype=core&format=json

release_iegrarwmwrhnvbp4jhxondwm2e

14 January 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/iegrarwmwrhnvbp4jhxondwm2e

24 November 2022

mapped directly with Wikidata item

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18824585%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

1 reference