HIF-regulated HO-1 gene transfer improves the post-ischemic limb recovery and diminishes TLR-triggered immune responses - Effects modified by concomitant VEGF overexpression (Q45874938)

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scientific article published on 10 April 2015

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English	HIF-regulated HO-1 gene transfer improves the post-ischemic limb recovery and diminishes TLR-triggered immune responses - Effects modified by concomitant VEGF overexpression	scientific article published on 10 April 2015

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scholarly article

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Europe PubMed Central

17 December 2017

http://europepmc.org/abstract/MED/25869523

HIF-regulated HO-1 gene transfer improves the post-ischemic limb recovery and diminishes TLR-triggered immune responses - Effects modified by concomitant VEGF overexpression (English)

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Europe PubMed Central

17 December 2017

http://europepmc.org/abstract/MED/25869523

toll-like receptor

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based on heuristic

inferred from title

Alicja Józkowicz

6

object named as

Alicja Jozkowicz

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Europe PubMed Central

17 December 2017

7

object named as

Jozef Dulak

1 reference

Europe PubMed Central

17 December 2017

http://europepmc.org/abstract/MED/25869523

Karolina Bukowska-Strakova

4

object named as

Karolina Bukowska-Strakova

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17 December 2017

http://europepmc.org/abstract/MED/25869523

5

object named as

Chantal Pichon

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Europe PubMed Central

17 December 2017

http://europepmc.org/abstract/MED/25869523

Mateusz Tomczyk

3

object named as

Mateusz Tomczyk

1 reference

Europe PubMed Central

17 December 2017

http://europepmc.org/abstract/MED/25869523

Agnieszka Jaźwa-Kusior

1

object named as

Agnieszka Jazwa

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Europe PubMed Central

17 December 2017

http://europepmc.org/abstract/MED/25869523

author name string

Mateusz Stoszko

2

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17 December 2017

http://europepmc.org/abstract/MED/25869523

publication date

10 April 2015

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Europe PubMed Central

17 December 2017

http://europepmc.org/abstract/MED/25869523

Vascular Pharmacology

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17 December 2017

http://europepmc.org/abstract/MED/25869523

71

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17 December 2017

http://europepmc.org/abstract/MED/25869523

127-138

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Europe PubMed Central

17 December 2017

http://europepmc.org/abstract/MED/25869523

Preventing leg amputations in critical limb ischemia with below-the-knee drug-eluting stents: the PaRADISE (PReventing Amputations using Drug eluting StEnts) trial

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Current gene therapy trials for vascular diseases

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Carbon monoxide generated by heme oxygenase 1 suppresses endothelial cell apoptosis.

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Heme oxygenase/carbon monoxide-biliverdin pathway down regulates neutrophil rolling, adhesion and migration in acute inflammation.

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Carbon monoxide has anti-inflammatory effects involving the mitogen-activated protein kinase pathway

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Carbon monoxide and dilation of blood vessels

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Heme oxygenase activity modulates vascular endothelial growth factor synthesis in vascular smooth muscle cells

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Stromal cell-derived factor 1 promotes angiogenesis via a heme oxygenase 1-dependent mechanism

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Role of vascular endothelial growth factor in the regulation of angiogenesis

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Cardiovascular gene therapy with vascular endothelial growth factors

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Combined delivery of heme oxygenase-1 gene and fibroblast growth factor-2 protein for therapeutic angiogenesis

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Facilitated angiogenesis induced by heme oxygenase-1 gene transfer in a rat model of hindlimb ischemia

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Reversal of HO-1 related cytoprotection with increased expression is due to reactive iron.

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VEGF gene delivery to myocardium: deleterious effects of unregulated expression

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Long-term VEGF-A expression promotes aberrant angiogenesis and fibrosis in skeletal muscle

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Hypoxia-regulated therapeutic gene as a preemptive treatment strategy against ischemia/reperfusion tissue injury.

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Pre-emptive hypoxia-regulated HO-1 gene therapy improves post-ischaemic limb perfusion and tissue regeneration in mice

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Adeno-associated viral vector-mediated hypoxia response element-regulated gene expression in mouse ischemic heart model

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Nanoparticle based delivery of hypoxia-regulated VEGF transgene system combined with myoblast engraftment for myocardial repair

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Combined vascular endothelial growth factor-A and fibroblast growth factor 4 gene transfer improves wound healing in diabetic mice

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Arteriogenic therapy based on simultaneous delivery of VEGF-A and FGF4 genes improves the recovery from acute limb ischemia

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Induction of functional neovascularization by combined VEGF and angiopoietin-1 gene transfer using AAV vectors.

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The therapeutic effect of vascular endothelial growth factor gene- or heme oxygenase-1 gene-modified endothelial progenitor cells on neovascularization of rat hindlimb ischemia model

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Heme oxygenase 1 is required for mammalian iron reutilization

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An optimized extended DNA kappa B site that enhances plasmid DNA nuclear import and gene expression.

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Heme oxygenase-1 inhibits myoblast differentiation by targeting myomirs.

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Ultrasound and microbubble-assisted gene delivery in Achilles tendons: long lasting gene expression and restoration of fibromodulin KO phenotype.

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Sonoporation: mechanistic insights and ongoing challenges for gene transfer

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Regulation of collateral blood vessel development by the innate and adaptive immune system

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Carbon monoxide differentially inhibits TLR signaling pathways by regulating ROS-induced trafficking of TLRs to lipid rafts

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Interactions between bacterial CpG-DNA and TLR9 bridge innate and adaptive immunity

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LPS/TLR4 signal transduction pathway

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Chemokine receptor CCR2 involvement in skeletal muscle regeneration

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The molecular regulation of myogenesis

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Gene therapy progress and prospects: ultrasound for gene transfer

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Microbubble attenuation and destruction: are they involved in sonoporation efficiency?

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Vascular endothelial growth factor reduced hypoxia-induced death of human myoblasts and improved their engraftment in mouse muscles

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Oxygen sensing in the hypoxic response pathway: regulation of the hypoxia-inducible transcription factor

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Angiogenesis and the ischaemic heart

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Heme oxygenase-1 modulates early inflammatory responses: evidence from the heme oxygenase-1-deficient mouse

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Hemodynamic forces induce the expression of heme oxygenase in cultured vascular smooth muscle cells

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Bacterial lipopolysaccharide copurifies with plasmid DNA: implications for animal models and human gene therapy

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Renal hemodynamic, inflammatory, and apoptotic responses to lipopolysaccharide in HO-1-/- mice

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Heme oxygenase-1 modulates the expression of adhesion molecules associated with endothelial cell activation.

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Myogenic satellite cells: physiology to molecular biology

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Time course of skeletal muscle repair and gene expression following acute hind limb ischemia in mice

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Adaptive myogenesis under hypoxia

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7 January 2021

Identifiers

10.1016/J.VPH.2015.02.011

1 reference

Europe PubMed Central

17 December 2017

http://europepmc.org/abstract/MED/25869523

1 reference

Europe PubMed Central

17 December 2017

http://europepmc.org/abstract/MED/25869523

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