Re-educating immunity in respiratory allergies: the potential for hematopoietic stem cell-mediated gene therapy. (Q45874675)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29150718%20AND%20SRC:MED&resulttype=core&format=json

3 April 2020

title

Re-educating immunity in respiratory allergies: the potential for hematopoietic stem cell-mediated gene therapy (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29150718%20AND%20SRC:MED&resulttype=core&format=json

3 April 2020

0 references

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29150718%20AND%20SRC:MED&resulttype=core&format=json

3 April 2020

Raymond J Steptoe

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29150718%20AND%20SRC:MED&resulttype=core&format=json

3 April 2020

author name string

Jeremy F Brooks

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29150718%20AND%20SRC:MED&resulttype=core&format=json

3 April 2020

James W Wells

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29150718%20AND%20SRC:MED&resulttype=core&format=json

3 April 2020

publication date

17 November 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29150718%20AND%20SRC:MED&resulttype=core&format=json

Journal of Molecular Medicine

3 April 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29150718%20AND%20SRC:MED&resulttype=core&format=json

3 April 2020

volume

96

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29150718%20AND%20SRC:MED&resulttype=core&format=json

3 April 2020

page(s)

21-30

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29150718%20AND%20SRC:MED&resulttype=core&format=json

3 April 2020

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29150718%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1007/s00109-017-1611-8

3 April 2020

exact match

0 references

cites work

Allergens and the airway epithelium response: gateway to allergic sensitization

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

Effects of an interleukin-5 blocking monoclonal antibody on eosinophils, airway hyper-responsiveness, and the late asthmatic response.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

The effects of an anti-IL-13 mAb on cytokine levels and nasal symptoms following nasal allergen challenge

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

TH2, allergy and group 2 innate lymphoid cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

IgE, mast cells, basophils, and eosinophils

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

IgE in allergy and asthma today

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

Type 2 cytokines: mechanisms and therapeutic strategies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

IgE⁺ memory B cells and plasma cells generated through a germinal-center pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

Omalizumab in severe allergic asthma inadequately controlled with standard therapy: a randomized trial.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

Omalizumab rapidly decreases nasal allergic response and FcepsilonRI on basophils.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

Omalizumab treatment downregulates dendritic cell FcepsilonRI expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

Compliance with national asthma management guidelines and specialty care: a health maintenance organization experience

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

Autoreactive T cells in healthy individuals

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

Functional anergy in a subpopulation of naive B cells from healthy humans that express autoreactive immunoglobulin receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

Most lymphoid organ dendritic cell types are phenotypically and functionally immature.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

Dendritic cells induce peripheral T cell unresponsiveness under steady state conditions in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

Resting dendritic cells induce peripheral CD8+ T cell tolerance through PD-1 and CTLA-4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

Cognate CD4+ help elicited by resting dendritic cells does not impair the induction of peripheral tolerance in CD8+ T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

Peripheral deletion of autoreactive CD8 T cells by cross presentation of self-antigen occurs by a Bcl-2-inhibitable pathway mediated by Bim

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

Transcriptional targeting of B cells for induction of peripheral CD8 T cell tolerance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

Induced CD4+Foxp3+ regulatory T cells in immune tolerance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

Regulatory T cell clones induced by oral tolerance: suppression of autoimmune encephalomyelitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

B cells regulate autoimmunity by provision of IL-10.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

Relation of CD4+CD25+ regulatory T-cell suppression of allergen-driven T-cell activation to atopic status and expression of allergic disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

Immune responses in healthy and allergic individuals are characterized by a fine balance between allergen-specific T regulatory 1 and T helper 2 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

Breakdown of self-tolerance in anergic B lymphocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

Monophosphorylation of CD79a and CD79b ITAM motifs initiates a SHIP-1 phosphatase-mediated inhibitory signaling cascade required for B cell anergy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

Continuous inhibitory signaling by both SHP-1 and SHIP-1 pathways is required to maintain unresponsiveness of anergic B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

Expansion or elimination of B cells in vivo: dual roles for CD40- and Fas (CD95)-ligands modulated by the B cell antigen receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

Competition for follicular niches excludes self-reactive cells from the recirculating B-cell repertoire.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

Immunoglobulin signal transduction guides the specificity of B cell-T cell interactions and is blocked in tolerant self-reactive B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

Antigen-induced exclusion from follicles and anergy are separate and complementary processes that influence peripheral B cell fate

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

Deletion and anergy of polyclonal B cells specific for ubiquitous membrane-bound self-antigen

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

Elimination from peripheral lymphoid tissues of self-reactive B lymphocytes recognizing membrane-bound antigens

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

Mucosal expression of DEC-205 targeted allergen alleviates an asthmatic phenotype in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

Regulatory T cells can migrate to follicles upon T cell activation and suppress GC-Th cells and GC-Th cell-driven B cell responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

Suppression by TFR cells leads to durable and selective inhibition of B cell effector function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

Foxp3+ follicular regulatory T cells control the germinal center response.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

T follicular regulatory cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

Regulatory T cells use programmed death 1 ligands to directly suppress autoreactive B cells in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

Intralymphatic allergen-specific immunotherapy: an effective and safe alternative treatment route for pollen-induced allergic rhinitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

Role of interleukin 10 in specific immunotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

Allergen immunotherapy decreases interleukin 4 production in CD4+ T cells from allergic individuals

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

IgG4 production is confined to human IL-10-producing regulatory B cells that suppress antigen-specific immune responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

Recurrence of type 1 diabetes after simultaneous pancreas-kidney transplantation, despite immunosuppression, is associated with autoantibodies and pathogenic autoreactive CD4 T-cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

Cutting edge: increased expression of Bcl-2 in antigen-specific memory CD8+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

Bone marrow-resident memory T cells survive pretransplant chemotherapy and contribute to early immune reconstitution of patients with acute myeloid leukemia given mafosfamide-purged autologous bone marrow transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

Targeting T-cell memory: where do we stand?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

Costimulation blockade, busulfan, and bone marrow promote titratable macrochimerism, induce transplantation tolerance, and correct genetic hemoglobinopathies with minimal myelosuppression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

Primed allospecific T cells prevent the effects of costimulatory blockade on prolonged cardiac allograft survival in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

Allograft rejection mediated by memory T cells is resistant to regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

Relative resistance of human CD4(+) memory T cells to suppression by CD4(+) CD25(+) regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

Maintenance of serological memory by polyclonal activation of human memory B cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

Intrinsic differences in the proliferation of naive and memory human B cells as a mechanism for enhanced secondary immune responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

Memory B cells are biased towards terminal differentiation: a strategy that may prevent repertoire freezing

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

Activation of Virus-specific Memory B Cells in the Absence of T Cell Help

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

Costimulation blockade inhibits allergic sensitization but does not affect established allergy in a murine model of grass pollen allergy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

Persistence of IgE-associated allergy and allergen-specific IgE despite CD4+ T cell loss in AIDS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

IgE responses to exogenous and endogenous allergens in atopic dermatitis patients under long-term systemic cyclosporine A treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

Lifetime of plasma cells in the bone marrow.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

Humoral immunity due to long-lived plasma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

Short-lived plasmablasts and long-lived plasma cells contribute to chronic humoral autoimmunity in NZB/W mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

Antigen-selected, immunoglobulin-secreting cells persist in human spleen and bone marrow.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

Efficacy of B-cell-targeted therapy with rituximab in patients with rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

Shared genetic variants suggest common pathways in allergy and autoimmune diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

Antigen-specific immunotherapy of autoimmune and allergic diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

Tolerance is established in polyclonal CD4(+) T cells by distinct mechanisms, according to self-peptide expression patterns

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

Steady-state antigen-expressing dendritic cells terminate CD4+ memory T-cell responses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

Targeting antigen to diverse APCs inactivates memory CD8+ T cells without eliciting tissue-destructive effector function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

Tolerance induction of IgG+ memory B cells by T cell-independent type II antigens

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

Autologous stem cell transplantation in autoimmune diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

Induction of antigen-specific tolerance through hematopoietic stem cell-mediated gene therapy: the future for therapy of autoimmune disease?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

Tolerance induction with gene-modified stem cells and immune-preserving conditioning in primed mice: restricting antigen to differentiated antigen-presenting cells permits efficacy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

Gene therapy delivery of myelin oligodendrocyte glycoprotein (MOG) via hematopoietic stem cell transfer induces MOG-specific B cell deletion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

Inhibition of xenoreactive natural antibody production by retroviral gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

Transfer of hematopoietic stem cells encoding autoantigen prevents autoimmune diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

Tolerization of a type I allergic immune response through transplantation of genetically modified hematopoietic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

Nonmyeloablative conditioning generates autoantigen-encoding bone marrow that prevents and cures an experimental autoimmune disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

Induction of tolerance to factor VIII inhibitors by gene therapy with immunodominant A2 and C2 domains presented by B cells as Ig fusion proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

Short-course rapamycin treatment enables engraftment of immunogenic gene-engineered bone marrow under low-dose irradiation to permit long-term immunological tolerance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

Antigen-encoding bone marrow terminates islet-directed memory CD8+ T-cell responses to alleviate islet transplant rejection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

Allergen-encoding bone marrow transfer inactivates allergic T cell responses, alleviating airway inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

Gene Therapy-Induced Antigen-Specific Tregs Inhibit Neuro-inflammation and Reverse Disease in a Mouse Model of Multiple Sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

Transplantation of retrovirally transduced bone marrow prevents autoimmune disease in aged mice by peripheral tolerance mechanisms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

Dynamic regulation of T follicular regulatory cell responses by interleukin 2 during influenza infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

Therapeutic haemoglobin synthesis in beta-thalassaemic mice expressing lentivirus-encoded human beta-globin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

Targeting MOG expression to dendritic cells delays onset of experimental autoimmune disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

Differential antigen processing by dendritic cell subsets in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

Direct expansion of functional CD25+ CD4+ regulatory T cells by antigen-processing dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

Antigen delivery via two molecules on the CD8- dendritic cell subset induces humoral immunity in the absence of conventional "danger".

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

Tolerance induction by lentiviral gene therapy with a nonmyeloablative regimen

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

Cellular players of hematopoietic stem cell mobilization in the bone marrow niche.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

Genetic Engineering and Manufacturing of Hematopoietic Stem Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

Treating Immunodeficiency through HSC Gene Therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

Safe and efficient generation of recombinant retroviruses with amphotropic and ecotropic host ranges

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

Clinical efficacy of gene-modified stem cells in adenosine deaminase-deficient immunodeficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

Twenty-Five Years of Gene Therapy for ADA-SCID: From Bubble Babies to an Approved Drug.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

A modified γ-retrovirus vector for X-linked severe combined immunodeficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

Outcomes following gene therapy in patients with severe Wiskott-Aldrich syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

Lentiviral hematopoietic stem cell gene therapy in patients with Wiskott-Aldrich syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

Angiopoietin-like protein 3 promotes preservation of stemness during ex vivo expansion of murine hematopoietic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

Efficient Ex Vivo Engineering and Expansion of Highly Purified Human Hematopoietic Stem and Progenitor Cell Populations for Gene Therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

Lentiviral-mediated gene therapy restores B cell tolerance in Wiskott-Aldrich syndrome patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

CD34+ cells from dental pulp stem cells with a ZFN-mediated and homology-driven repair-mediated locus-specific knock-in of an artificial β-globin gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

Efficient genome editing in hematopoietic stem cells with helper-dependent Ad5/35 vectors expressing site-specific endonucleases under microRNA regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

Preclinical modeling highlights the therapeutic potential of hematopoietic stem cell gene editing for correction of SCID-X1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

Targeted genome editing restores T cell differentiation in a humanized X-SCID pluripotent stem cell disease model

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

Haematopoietic stem and progenitor cells from human pluripotent stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

In vivo transduction of primitive mobilized hematopoietic stem cells after intravenous injection of integrating adenovirus vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

Steady-state dendritic cells expressing cognate antigen terminate memory CD8+ T-cell responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-017-1611-8

The radiation resistance of long-lived lymphocytes and plasma cells in mouse and rat lymph nodes.

21 January 2018

1 reference

12 December 2020

Cutting edge: direct suppression of B cells by CD4+ CD25+ regulatory T cells

1 reference

12 December 2020

Steady-state dendritic cells continuously inactivate T cells that escape thymic negative selection

1 reference

12 December 2020

Effect of an interleukin-4 variant on late phase asthmatic response to allergen challenge in asthmatic patients: results of two phase 2a studies

1 reference

12 December 2020

Mechanisms of allergen-specific immunotherapy

1 reference

12 December 2020

Defective TCR stimulation in anergized type 2 T helper cells correlates with abrogated p56(lck) and ZAP-70 tyrosine kinase activities.

1 reference

12 December 2020

Role of the mammalian target of rapamycin pathway in lentiviral vector transduction of hematopoietic stem cells

1 reference

12 December 2020

Integrated signals between IL-13, IL-4, and IL-5 regulate airways hyperreactivity

1 reference

12 December 2020

Quiescent memory B cells in human peripheral blood co-express bcl-2 and bcl-x(L) anti-apoptotic proteins at high levels.

1 reference

12 December 2020

A role for Toll-like receptors in acquired immunity: up-regulation of TLR9 by BCR triggering in naive B cells and constitutive expression in memory B cells

1 reference

12 December 2020

CD8+ memory T cells (CD44high, Ly-6C+) are more sensitive than naive cells to (CD44low, Ly-6C-) to TCR/CD8 signaling in response to antigen.

1 reference

12 December 2020

Intra-bone marrow injection of allogeneic bone marrow cells: a powerful new strategy for treatment of intractable autoimmune diseases in MRL/lpr mice

1 reference

12 December 2020

Maintenance of B cell anergy requires constant antigen receptor occupancy and signaling

1 reference

12 December 2020

Naive versus memory CD4 T cell response to antigen. Memory cells are less dependent on accessory cell costimulation and can respond to many antigen-presenting cell types including resting B cells

1 reference

12 December 2020

Islet transplantation in patients with autoimmune diabetes induces homeostatic cytokines that expand autoreactive memory T cells

1 reference

12 December 2020